Multi-factorial optimization of imaging parameters for quantifying coronary stenosis in cardiac CT

2021 ◽  
Author(s):  
Mojtaba Zarei ◽  
Ehsan Abadi ◽  
William P. Segars ◽  
Taylor Richards ◽  
Ehsan Samei
Keyword(s):  
Coronary Stenosis ◽  
Cardiac Ct ◽  
Imaging Parameters ◽  
Factorial Optimization

Radiation Damage of Support Films

1981 ◽  
Vol 39 ◽  
pp. 28-29
Author(s):  
H.A. Cohen ◽  
W. Chiu
Keyword(s):  
Transfer Function ◽  
Low Temperatures ◽  
Carbon Support ◽  
Contrast Transfer Function ◽  
Electron Dose ◽  
Imaging Parameters ◽  
Negative Stain ◽  
Phase Corrections ◽  
Two Parameters ◽  
Medium Dose

The goal of imaging the finest detail possible in biological specimens leads to contradictory requirements for the choice of an electron dose. The dose should be as low as possible to minimize object damage, yet as high as possible to optimize image statistics. For specimens that are protected by low temperatures or for which the low resolution associated with negative stain is acceptable, the first condition may be partially relaxed, allowing the use of (for example) 6 to 10 e/Å2. However, this medium dose is marginal for obtaining the contrast transfer function (CTF) of the microscope, which is necessary to allow phase corrections to the image. We have explored two parameters that affect the CTF under medium dose conditions.Figure 1 displays the CTF for carbon (C, row 1) and triafol plus carbon (T+C, row 2). For any column, the images to which the CTF correspond were from a carbon covered hole (C) and the adjacent triafol plus carbon support film (T+C), both recorded on the same micrograph; therefore the imaging parameters of defocus, illumination angle, and electron statistics were identical.

Criteria Elucidate the Role of Cardiac CT and MR

2006 ◽  
Vol 39 (21) ◽  
pp. 43
Author(s):  
KERRI WACHTER
Keyword(s):  
Cardiac Ct
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