Differential Mueller-matrix tomography of the polycrystalline structure of histological sections in the histological determination of the limitation of the damage formation of human internal organs

2020 ◽  
Author(s):  
A. Litvinenko ◽  
Ivan Savka ◽  
Yuriy Ushenko ◽  
Olexander V. Dubolazov ◽  
Oleg Wanchulyak ◽  
...  
Keyword(s):  
Mueller Matrix ◽  
Polycrystalline Structure ◽  
Internal Organs ◽  
Histological Sections

scholarly journals Differential Mueller matrix imaging of partially depolarizing optically anisotropic biological tissues

2019 ◽  
Vol 35 (4) ◽  
pp. 877-891 ◽  
Author(s):  
L. Trifonyuk ◽  
A. Sdobnov ◽  
W. Baranowski ◽  
V. Ushenko ◽  
O. Olar ◽  
...  
Keyword(s):  
Biological Tissues ◽  
Mueller Matrix ◽  
Differential Diagnostics ◽  
Matrix Elements ◽  
Polycrystalline Structure ◽  
First Order ◽  
Histological Sections ◽  
Laser Polarimetry ◽  
Matrix Mapping ◽  
Differential Matrix

AbstractSince recently, a number of innovative polarization-based optical imaging modalities have been introduced and extensively used in various biomedical applications, with an ultimate aim to attain the practical tool for the optical biopsy and functional characterization of biological tissues. The techniques utilize polarization properties of light and Mueller matrix mapping of microscopic images of histological sections of biological tissues or polycrystalline films of biological fluids. The main drawback of currently developed laser polarimetry approaches and Mueller matrix mapping techniques is poor reproducibility of experimental data. This is due to azimuthal dependence of polarization and ellipticity values of most matrix elements to sample orientation in respect to incidence light polarization. Current study aims to generalize the methods of laser polarimetry for diagnosis of partially depolarizing optically anisotropic biological tissues. A method of differential Mueller matrix mapping for reconstruction of linear and circular birefringence and dichroism parameter distributions of partially depolarizing layers of biological tissues of different morphological structure is introduced and practically implemented. The coordinate distributions of the value of the first-order differential matrix elements of histological sections of brain tissue with spatially structured, optically anisotropic fibrillar network, as well as of parenchymatous tissue of the rectum wall with an “islet” polycrystalline structure are determined. Within the statistical analysis of polarization reproduced distributions of the averaged parameters of phase and amplitude anisotropy, the significant sensitivity of the statistical moments of the third and fourth orders to changes in the polycrystalline structure of partially depolarizing layers of biological tissue is observed. The differentiation of female reproductive sphere connective tissue is realized with excellent accuracy. The differential Mueller matrix mapping method for reconstruction of distributions of linear and circular birefringence and dichroism parameters of partially depolarizing layers of biological tissues of different morphological structures is proposed and substantiated. Differential diagnostics of changes in the phase (good balanced accuracy) and amplitude (excellent balanced accuracy) of the anisotropy of the partially depolarizing layers of the vagina wall tissue with prolapse of the genitals is realized. The maximum diagnostic efficiency of the first-order differential matrix method was demonstrated in comparison with the traditional methods of polarization and Mueller matrix mapping of histological sections of light-scattering biological tissues.

scholarly journals Forensic determination of determination of damage to human internal organs by the method of reconstruction of the optical activity of histological sections

2021 ◽  
pp. 84-95
Author(s):  
Oleksandra Litvinenko ◽  
Oleh Vanchulyak ◽  
Yurii Ushenko ◽  
Artem Motrich
Keyword(s):  
Optical Activity ◽  
Histological Study ◽  
Molecular Complexes ◽  
Mean Value ◽  
Internal Organs ◽  
Histological Sections ◽  
Liver And Kidney ◽  
The Mean ◽  
The Brain

The article presents the results of experimental testing of the technique of tomographic reconstruction of circular birefringence maps of molecular complexes in a digital histological study of the age of damage to tissues of internal organs (brain, liver and kidney) of temporary monitoring of the mean value, dispersion, asymmetry and kurtosis, characterizing the distribution of the magnitude of the optical activity of histological sections of the brain, liver and kidney identification of the temporal extent of linear changes in statistical parameters and the accuracy of determining the duration of damage to human internal organs by digital histological methods of polarization reconstruction (tomography) of circular birefringence of molecular complexes. Aim of the work. Development of a technique for determining the duration of damage to human internal organs by digital histological methods of polarization reconstruction of circular birefringence of molecular complexes. Materials and methods. The object of the study was the histology of samples of human internal organs (brain, kidney and liver) with different duration of damage from 1 hour to 120 hours. For control, we used BT samples of those who died from coronary artery disease with different duration of damage from 1 hour to 120 hours. The studies were carried out using the technique of polarization reconstruction of circular birefringence of molecular complexes. Results. A set of treatment-relevant relationships between temporal changes in the statistical structure of topographic maps of circular birefringence of optically active molecular complexes of histological sections of human internal organs with different duration of damage and variations in the mean value, dispersion, asymmetry and kurtosis, characterizing the distribution of the value of this parameter of anisotropy, has been determined. Conclusions. A new original method has been developed for tomography of the optical activity of molecular complexes of tissues of human internal organs in a digital histological study of the age of damage to the tissues of the brain, liver and kidney, as well as the myocardium and lung tissue at a time interval of 1 hour. up to 120 hours

scholarly journals Universal Synthesizer of Mueller Matrices Based on the Symmetry Properties of the Enpolarizing Ellipsoid

Symmetry ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 983
Author(s):  
José J. Gil ◽  
Ignacio San José
Keyword(s):  
Mathematical Structure ◽  
Mueller Matrix ◽  
Morphological Properties ◽  
Nondestructive Analysis ◽  
Structural Decomposition ◽  
Symmetry Properties ◽  
Mueller Matrices ◽  
Scattering Measurement ◽  
The Way

Polarimetry is today a widely used and powerful tool for nondestructive analysis of the structural and morphological properties of a great variety of material samples, including aerosols and hydrosols, among many others. For each given scattering measurement configuration, absolute Mueller polarimeters provide the most complete polarimetric information, intricately encoded in the 16 parameters of the corresponding Mueller matrix. Thus, the determination of the mathematical structure of the polarimetric information contained in a Mueller matrix constitutes a topic of great interest. In this work, besides a structural decomposition that makes explicit the role played by the diattenuation-polarizance of a general depolarizing medium, a universal synthesizer of Muller matrices is developed. This is based on the concept of an enpolarizing ellipsoid, whose symmetry features are directly linked to the way in which the polarimetric information is organized.

scholarly journals DETERMINATION OF THE FREQUENCY OF STAB-CUT DAMAGES OF INTERNAL ORGANS AND THE CONDITIONS OF THEIR CAUSES

2020 ◽  
Author(s):  
Aleksey A. Devyaterikov
Keyword(s):  
Statistical Study ◽  
The Body ◽  
Average Depth ◽  
Internal Organs ◽  
Medical Examinations

Aim. Determination of the frequency of stab-cut damages of internal organs and the conditions of their causes. Material and methods. The article presents the results of a retrospective statistical study of the conclusions of the forensic medical examinations of the corpses of the Khabarovsk State Forensic Bureau for the period from 2014-2018. Results. The frequency of injury with sharp objects, the most commonly damaged internal organs during stab-cut wounds and the average depth of the wound channels both in the body as a whole and separately for internal organs were established in the course of the study.

scholarly journals Imaging Mueller matrix determination of transparent, unpolarizing samples using a classically entangled polarization state

2018 ◽  
Vol 64 (4) ◽  
pp. 407
Author(s):  
Jacqueline Isamar Muro-Ríos ◽  
R. Espinosa-Luna
Keyword(s):  
Open Space ◽  
Polarization State ◽  
Theoretical Work ◽  
Mueller Matrix ◽  
Experimental Setup ◽  
Wave Plate ◽  
Recent Theoretical Work ◽  
Study Results ◽  
Theoretical Proposal

Inspired in a recent theoretical work for the determination of the Mueller matrix, using as incidence a single classically entangled polarization state (F. Töppel et al., New J. Phys. 16 (2014) 073019), an experimental setup is proposed and tested.  The open space and two wave plate retarders are used as the transparent, nondepolarizing samples under study. Results show some experimental improvements are necessary in order to implement accurately the theoretical proposal in which this work is based.

Complete determination of the conical Mueller matrix for one-dimensional rough metallic surfaces

2006 ◽  
Vol 257 (1) ◽  
pp. 62-71 ◽  
Author(s):  
Rafael Espinosa-Luna ◽  
Gelacio Atondo-Rubio ◽  
Alberto Mendoza-Suárez
Keyword(s):  
Mueller Matrix ◽  
Metallic Surfaces ◽  
One Dimensional ◽  
Complete Determination

Mueller matrix decomposition for determination of optical rotation of glucose molecules in turbid media

2014 ◽  
Vol 19 (4) ◽  
pp. 046015 ◽  
Author(s):  
Ping Sun ◽  
Yongchao Ma ◽  
Wei Liu ◽  
Qinghua Yang ◽  
Qiongzhen Jia
Keyword(s):  
Optical Rotation ◽  
Matrix Decomposition ◽  
Mueller Matrix ◽  
Turbid Media
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