Numerical optimization of the dual-wavelengths copper vapor laser treatment of basal cell cancer

2019 ◽  
Author(s):  
Igor Ponomarev ◽  
Sergey . Topchiy ◽  
Mishik . Kazaryan ◽  
Aleksandra. E. Pushkareva ◽  
Svetlana V. Klyuchareva ◽  
...  
Keyword(s):  
Laser Treatment ◽  
Basal Cell ◽  
Numerical Optimization ◽  
Cell Cancer ◽  
Copper Vapor Laser ◽  
Vapor Laser ◽  
Basal Cell Cancer ◽  
Copper Vapor

scholarly journals Treatment of Basal Cell Cancer With a Pulsed Copper Vapor Laser: A Case Series

2019 ◽  
Vol 10 (4) ◽  
pp. 350-354
Author(s):  
Svetlana V. Klyuchareva ◽  
Igor V. Ponomarev ◽  
Sergey B. Topchiy ◽  
Alexandra E. Pushkareva ◽  
Yury N. Andrusenko
Keyword(s):  
Side Effects ◽  
Laser Treatment ◽  
Histological Examination ◽  
Basal Cell ◽  
Cell Cancer ◽  
Case Series ◽  
Copper Vapor Laser ◽  
Vapor Laser ◽  
Copper Vapor ◽  
Ocular Injuries

Introduction: Basal cell carcinoma (BCC) is the most prevalent form of non-melanoma skin cancer commonly arising in elderly patients. Currently, many laser systems are applied for the treatment of BCC. However, up to the present, there have been several reports concerning ocular side effects due to the laser procedure in the borders of the periorbital area. This determines the feasibility of testing new laser surgical modes for the management of periorbital BCC. This stuay aimed to estimate both the efficacy, the early post-radiated side effects and long-term outcomes of the CVL treatment of periorbital BCC. Patients and Methods: Two men and 6 women aged 50 to 77 years were diagnosed with periorbital BCC according to the data of both the clinical evaluation and histological examination of the tissue samples taken from the involved area. Six months after the laser treatment, the histological examination of skin samples from the borderline of the irradiated area was made again. All patients were followed for 24 months after the laser treatment of BCC. The laser treatment was administered during one session of copper vapor laser (CVL) (Yakhroma-Med model). The treatment included CVL radiation with a wavelength of 511 nm and 578 nm, in the ratio of 3:2. The power level was set up to 3 W, and the exposure time was equal from 200 to 600 ms. The pulse duration accounted for 15 ns. The diameter of the light spot on the skin surface amounted to 1 mm. Results: Dual-wavelengths CVL treatment of periorbital BCC provided a complete elimination of malignant cells and dysplastic vessels during one procedure. The duration of skin healing amounted to 2-4 weeks. There were neither ocular injuries or pronounced skin side effects nor relapses within 24 months after the laser procedure. Conclusion: CVL treatment of periorbital BCC provides relevant cosmetic results without ocular injuries and relapses.

scholarly journals Treatment of basal cell cancer in the periorbital area using a pulsed copper vapour laser

2019 ◽  
Vol 94 (6) ◽  
pp. 15-21 ◽  
Author(s):  
S. V. Klyuchareva ◽  
I. V. Ponomarev ◽  
S. B. Topchy ◽  
A. E. Pushkareva ◽  
Yu. N. Andrusenko
Keyword(s):  
Laser Treatment ◽  
Basal Cell ◽  
Near Infrared ◽  
Skin Diseases ◽  
Cell Cancer ◽  
Average Power ◽  
Basal Layer ◽  
Developed Countries ◽  
Copper Vapour Laser ◽  
Basal Cell Cancer

An increase in life expectancy in developed countries is inevitably accompanied by an increase in the number of nonmelanoma skin diseases, which are primarily represented by basal cell cancer (BCC) occurring in elderly and old-age patients. The pathogenesis of such diseases is associated both with impaired proliferation and differentiation of the keratinocytes of the epidermal basal layer, as well as with the transformation of the vasculature in the papillary dermis in the vicinity of BCC. In recent years, such conditions have been increasingly treated using CO2 , neodymium, diode and pulsed-dye lasers. In many cases, these devices allow malignant BCC cells to be successfully eliminated. However, the use of near-infrared lasers in the periorbital area is limited due to a higher risk of damaging the organs of the visual system. Therefore, a search for new laser surgery methods that can be used for treating malignant skin tumours seems to be a prospective research direction.Methods. 3 male and 9 female patients diagnosed with primary BCC were treated using a copper vapour laser (Yakhroma-Med). The age of the patients varied from 34 to 77 years. Laser treatment was carried out in one session under the following irradiation parameters: the wavelength of 511 and 578 nm, the average power of up to 3 W and a series of 15 ns pulses. The pause between the pulses was 60 μs, with the exposure time ranging from 200 to 600 ms. The light spot diameter on the skin surface was 1 mm. The follow-up monitoring duration was 24 months.Results. In all the BCC patients, one session of copper vapour laser treatment allowed malignant cells in the disease area to be completely eliminated without relapses during 2 years after the therapy. The duration of skin healing in the irradiated area was 2 weeks in patients under the age of 40 years, compared to 3–4 weeks in elderly patients. After the treatment, short-term side effects, such as a slight edema, erythema and peeling, were observed.

Comparative Histochemistry of Port-Wine Stains After Copper Vapor Laser (578 nm) and Argon Laser Treatment

1992 ◽  
Vol 99 (2) ◽  
pp. 160-167 ◽  
Author(s):  
Reinhard Anton Neumann ◽  
Robert Martin Knobler ◽  
Helmut Leonhartsberger ◽  
Walter Gebhart
Keyword(s):  
Laser Treatment ◽  
Argon Laser ◽  
Copper Vapor Laser ◽  
Port Wine ◽  
Vapor Laser ◽  
Port Wine Stains ◽  
Copper Vapor

scholarly journals Copper vapor laser treatment of granuloma of the vermilion border of the lips arising as a complication after permanent make-up

2021 ◽  
Vol 97 (1) ◽  
pp. 41-45
Author(s):  
Igor V. Ponomarev ◽  
Yury N. Andrusenko ◽  
Sergey B. Topchiy ◽  
Ludmila D. Shakina
Keyword(s):  
Side Effects ◽  
Laser Treatment ◽  
Histopathological Examination ◽  
Surgical Excision ◽  
Copper Vapor Laser ◽  
Cosmetic Result ◽  
Minimal Risk ◽  
Vapor Laser ◽  
Copper Vapor ◽  
Increased Risk

Background. Granulomas of the vermilion border of the lips (GVBL); as a complication of lip tattooing; inevitably poses cosmetic problems. Surgical excision and cryodestruction are associated with an increased risk of scarring and recurrence of GVBL. Laser therapy can selectively destroy a pigment and achieve the desired cosmetic result with minimal risk of side effects. So laser treatment was reported to be a more relevant method of treatment of GVBL. Aim. To evaluate the effectiveness of treatment of GVBL with copper vapor laser (CVL) radiation. Case report. 39-year-old female patient; without manifestations of systemic sarcoidosis; reported a 2-year history of granulomas of the lips vermilion border. She had a permanent makeup cosmetic tattoo before the onset of granulomas after lip tattooing. Histopathological examination revealed the presence of pigment in the upper and middle layers of the dermis. GVBL treatment was performed using a CVL during a single procedure; with an average CVL power of 0.60.8 W; with a ratio of 3:2 at wavelengths of 511 nm and 578 nm; exposure time 0.3 s. Light spot diameter 1 mm. CVL treatment led to a pronounced elimination of all GVBL without side effects within five years. Discussion. CVL allows a combined mode of exposure; consisting of grinding large granules of pigment to sizes that can be absorbed by the lymphatic system and suppressing VEGF expression using radiation with a wavelength of 578 nm. Conclusions. The CVL treatment provided an excellent cosmetic result due to selective photodestruction of the pigment and complete remodeling of the vascular bed associated with GVBL. The high clinical efficiency of eliminating post-tattooing foci of GVBL using CVL without side effects allows us to suggest this method for dermatologists and cosmetologists as a highly effective and inexpensive way to eliminate complications of permanent makeup.

scholarly journals Treatment of pyogenic granuloma with copper vapor laser radiation

2021 ◽  
Vol 97 (2) ◽  
pp. 41-49
Author(s):  
Igor V. Ponomarev ◽  
Ludmila D. Shakina ◽  
Sergey B. Topchiy ◽  
Svetlana V. Klyuchareva ◽  
Alexandra E. Pushkareva
Keyword(s):  
Clinical Practice ◽  
Side Effects ◽  
Laser Treatment ◽  
Postoperative Bleeding ◽  
Pyogenic Granuloma ◽  
Copper Vapor Laser ◽  
Surgical Removal ◽  
Vapor Laser ◽  
Copper Vapor ◽  
The Face

Background. Pyogenic granuloma (PG) or lobular capillary hemangioma, ICD10 code: L98.0. appears as a single bright red or violet papule up to 20 mm in size, on the face, fingers, skull surface, arms, and intergluteal fold, as well as on the oral mucous membranes. Surgical removal of facial PG is not always possible due to insufficient thickness of the dermis. Treatment of PG with a pulsed dye laser (PDL) or neodymium laser (Nd:YAG) can achieve a noticeable elimination of the lesion but is reported to be accompanied by such side effects as purpura or scarring. It determines the feasibility of introducing into clinical practice the methods of laser treatment of PG using the radiation of a copper vapor laser (CVL) with a wavelength of 578 nm, which effectively absorbed by the blood. Aim. The assessment of the clinical efficacy and safety of the CVL treating PG. Methods. 26 adult patients with PG in various parts of the face, including the lips, limbs, and trunk, were included in this study. PG treatment was carried out in one session with CVL (Yakhroma-Med, FIAN) at an average power of 0.71.0 W, at a wavelength of 578 nm, exposure time 0.20.3 s. The diameter of the light spot is 1 mm. Results. Immediately after the single laser treatment, the PG involved area became grey. In 710 days, the irradiated area was utterly similar to the adjacent intact skin. No postoperative bleeding or infection was noted. Side effects included mild skin atrophy. During the follow-up observation for five years, no side effects were found. Conclusion. The high efficiency of PG elimination using CVL in the absence of pronounced side effects allows suggesting this method for introducing into dermatologists and cosmetologists' clinical practice as a highly effective and inexpensive method of treatment.

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