Minimally invasive intraperitoneal photodynamic therapy using a new soft robot system

2020 ◽  
Author(s):  
Yang Liu ◽  
Kashu Yamazaki ◽  
Dawei Zhang ◽  
Yucheng Li ◽  
Meng Su ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Minimally Invasive ◽  
Soft Robot ◽  
Robot System

Optical Properties of Photodynamic Therapy Drugs in Different Environments: The Paradigmatic Case of Temoporfin

2020 ◽  
Author(s):  
busenur Aslanoglu ◽  
Ilya Yakavets ◽  
Vladimir Zorin ◽  
Henri-Pierre Lassalle ◽  
Francesca Ingrosso ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Optical Properties ◽  
Photodynamic Therapy ◽  
Minimally Invasive ◽  
Visible Light ◽  
Cancer Treatment ◽  
Singlet Oxygen ◽  
Tumor Cells ◽  
Molecular Oxygen ◽  
Computational Tools

Computational tools have been used to study the photophysical and photochemical features of photosensitizers in photodynamic therapy (PDT) –a minimally invasive, less aggressive alternative for cancer treatment. PDT is mainly based by the activation of molecular oxygen through the action of a photoexcited sensitizer (photosensitizer). Temoporfin, widely known as mTHPC, is a second-generation photosensitizer, which produces the cytotoxic singlet oxygen when irradiated with visible light and hence destroys tumor cells. However, the bioavailability of the mostly hydrophobic photosensitizer, and hence its incorporation into the cells, is fundamental to achieve the desired effect on malignant tissues by PDT. In this study, we focus on the optical properties of the temoporfin chromophore in different environments –in <i>vacuo</i>, in solution, encapsulated in drug delivery agents, namely cyclodextrin, and interacting with a lipid bilayer.

Lapabot: A compact telesurgical robot system for minimally invasive surgery: Part II. Telesurgery evaluation

2011 ◽  
Vol 21 (3) ◽  
pp. 195-200 ◽  
Author(s):  
Jun Woo Park ◽  
Duck Hee Lee ◽  
Young Woo Kim ◽  
Byeong Han Lee ◽  
Yung Ho Jo
Keyword(s):  
Minimally Invasive Surgery ◽  
Minimally Invasive ◽  
Invasive Surgery ◽  
Robot System

Minimally Invasive Photodynamic Therapy (PDT) for Ablation of Experimental Rat Glioma

2006 ◽  
Vol 49 (3) ◽  
pp. 135-142 ◽  
Author(s):  
H. Hirschberg ◽  
S. Spetalen ◽  
S. Carper ◽  
P. Hole ◽  
T. Tillung ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Minimally Invasive ◽  
Rat Glioma

Multi-robot system optimization based on redundant serial spherical mechanism for robotic minimally invasive surgery

Robotica ◽  
2018 ◽  
Vol 37 (7) ◽  
pp. 1202-1213 ◽  
Author(s):  
C. A. Nelson ◽  
M. A. Laribi ◽  
S. Zeghloul
Keyword(s):  
Minimally Invasive Surgery ◽  
Minimally Invasive ◽  
Invasive Surgery ◽  
System Optimization ◽  
Design Parameters ◽  
Operating Table ◽  
Robot System ◽  
Spherical Linkages ◽  
Spherical Mechanism ◽  
Multi Robot

SUMMARYSerial spherical linkages have been used in the design of a number of robots for minimally invasive surgery, in order to mechanically constrain the surgical instrument with respect to the incision. However, the typical serial spherical mechanism suffers from conflicting design objectives, resulting in an unsuitable compromise between avoiding collision with the patient and producing good kinematic and workspace characteristics. In this paper, we propose a multi-robot system composed of two redundant serial spherical linkages to achieve this purpose. A multi-objective optimization for achieving the aforementioned design goals is presented first for a single redundant robot and then for a multi-robot system. The problem of mounting multiple robots on the operating table as well as the way cooperative actions can be performed is addressed. The sensitivity of each optimal solution (single-robot and multi-robot) to uncertainties in the design parameters is investigated.

Design and Analysis for Minimally Invasive Vascular Interventional Surgical Robot System

2012 ◽  
Vol 8 (1) ◽  
pp. 31-36
Author(s):  
Hongbo Wang ◽  
Xue Yang ◽  
Xiaoqian Zheng ◽  
Ning Du ◽  
Hongwei Zhen ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Surgical Robot ◽  
Robot System
Sign in / Sign up

Export Citation Format

Share Document