Label-free ultrasensitive detection of Amyloid-β using microtoroid resonators with lipid surface functionalization (Conference Presentation)

2020 ◽  
Author(s):  
Adley Gin ◽  
Phuong-Diem Nguyen ◽  
Tsu-Te Judith Su
Keyword(s):  
Surface Functionalization ◽  
Amyloid Β ◽  
Ultrasensitive Detection ◽  
Label Free ◽  
Lipid Surface

A photoelectrochemical immunosensor based on CdS/CdTe-cosensitized SnO2 as a platform for the ultrasensitive detection of amyloid β-protein

The Analyst ◽  
2020 ◽  
Vol 145 (2) ◽  
pp. 619-625 ◽  
Author(s):  
Nuo Zhang ◽  
Yaoguang Wang ◽  
Guanhui Zhao ◽  
Chao Wang ◽  
Yueyuan Li ◽  
...  
Keyword(s):  
Amyloid Β ◽  
Ultrasensitive Detection ◽  
Amyloid Β Protein ◽  
Label Free ◽  
Β Protein

An ultrasensitive label-free photoelectrochemical immunosensor was developed to detect amyloid β-protein based on CdS/CdTe-cosensitized SnO2 nanoflowers.

scholarly journals The Role of Surface Chemistry in the Efficacy of Protein and DNA Microarrays for Label-Free Detection: An Overview

Polymers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1026
Author(s):  
Elisa Chiodi ◽  
Allison M. Marn ◽  
Matthew T. Geib ◽  
M. Selim Ünlü
Keyword(s):  
Surface Chemistry ◽  
Surface Functionalization ◽  
Dna Microarrays ◽  
Label Free ◽  
Polymeric Coatings ◽  
Label Free Detection ◽  
Particle Imaging ◽  
Single Particle Imaging ◽  
The Impact

The importance of microarrays in diagnostics and medicine has drastically increased in the last few years. Nevertheless, the efficiency of a microarray-based assay intrinsically depends on the density and functionality of the biorecognition elements immobilized onto each sensor spot. Recently, researchers have put effort into developing new functionalization strategies and technologies which provide efficient immobilization and stability of any sort of molecule. Here, we present an overview of the most widely used methods of surface functionalization of microarray substrates, as well as the most recent advances in the field, and compare their performance in terms of optimal immobilization of the bioreceptor molecules. We focus on label-free microarrays and, in particular, we aim to describe the impact of surface chemistry on two types of microarray-based sensors: microarrays for single particle imaging and for label-free measurements of binding kinetics. Both protein and DNA microarrays are taken into consideration, and the effect of different polymeric coatings on the molecules’ functionalities is critically analyzed.

A novel label free long non-coding RNA electrochemical biosensor based on green l-cysteine electrodeposition and Au–Rh hollow nanospheres as tags

RSC Advances ◽  
2015 ◽  
Vol 5 (64) ◽  
pp. 51990-51999 ◽  
Author(s):  
Fei Liu ◽  
Guiming Xiang ◽  
Liqun Zhang ◽  
Dongneng Jiang ◽  
Linlin Liu ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Single Wall Carbon Nanotubes ◽  
Complex Signal ◽  
Ultrasensitive Detection ◽  
Label Free ◽  
Hollow Nanospheres ◽  
Non Coding Rna ◽  
Long Non Coding Rna

lncRNA biosensor based on single-wall carbon nanotubes wrapped with Au–Rh hollow nanospheres (Au/Rh-HNP@SWCNT) complex signal amplification and an l-Cys Au nano-film provided ultrasensitive detection for the nuclear paraspeckle assembly transcript 1 (NEAT1).

Construction of electrochemical immunosensor based on redox hydrogel for ultrasensitive detection of carcinoembryonic antigen

2021 ◽  
Author(s):  
Xiangrong Huang ◽  
Na Wu ◽  
Wenxiu Liu ◽  
Yazhuo Shang ◽  
Honglai Liu ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Carcinoembryonic Antigen ◽  
Electrochemical Detection ◽  
Electrochemical Immunosensor ◽  
Ultrasensitive Detection ◽  
Label Free

In this work, a novel redox hydrogel was proposed for ultrasensitive label-free electrochemical detection of carcinoembryonic antigen (CEA). The redox hydrogel composed by cellulose nanocrystalline (CNC), methylene blue (MB), multi-walled...

Label-free electrochemical immunosensor based on gold nanoparticle/polyethyleneimine/reduced graphene oxide nanocomposite for the ultrasensitive detection of cancer biomarker matrix metalloproteinase-1

The Analyst ◽  
2021 ◽  
Author(s):  
Xinke Liu ◽  
Lu-Yin Lin ◽  
Fu-Yen Tseng ◽  
Yu-Cheng Tan ◽  
Jian Li ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Matrix Metalloproteinase ◽  
Gold Nanoparticle ◽  
Reduced Graphene Oxide ◽  
Electrochemical Immunosensor ◽  
Ultrasensitive Detection ◽  
Label Free ◽  
Matrix Metalloproteinase 1 ◽  
Reduced Graphene ◽  
P Matrix

Matrix metalloproteinase-1 (MMP-1) is associated with many types of cancers, including oral, colorectal, and brain cancers. This paper describes the fabrication of an MMP-1 immunosensor based on a gold nanoparticle/polyethyleneimine/reduced...

An electrochemical impedance sensor for the label-free ultrasensitive detection of interleukin-6 antigen

2013 ◽  
Vol 178 ◽  
pp. 310-315 ◽  
Author(s):  
Ting Yang ◽  
Shun Wang ◽  
Huile Jin ◽  
Weiwei Bao ◽  
Shaoming Huang ◽  
...  
Keyword(s):  
Interleukin 6 ◽  
Electrochemical Impedance ◽  
Ultrasensitive Detection ◽  
Label Free ◽  
Impedance Sensor

scholarly journals Infrared Plasmonic Biosensor with Tetrahedral DNA Nanostructure as Carriers for Label‐Free and Ultrasensitive Detection of miR‐155

2021 ◽  
pp. 2100583
Author(s):  
Xindan Hui ◽  
Cheng Yang ◽  
Dongxiao Li ◽  
Xianming He ◽  
He Huang ◽  
...  
Keyword(s):  
Ultrasensitive Detection ◽  
Label Free ◽  
Dna Nanostructure
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