A personalized approach for microwave ablation treatment planning fusing radiomics and bioheat transfer modeling

Author(s):  
Pinyo Taeprasartsit ◽  
Chanok Pathompatai ◽  
Kasidit Jusomjai ◽  
Henky Wibowo ◽  
Jan Sebek ◽  
...  
2021 ◽  
Author(s):  
Jan Sebek ◽  
Pinyo Taeprasartsit ◽  
Henky Wibowo ◽  
Warren L. Beard ◽  
Radoslav Bortel ◽  
...  

CHEST Journal ◽  
2021 ◽  
Vol 160 (4) ◽  
pp. A1627-A1628
Author(s):  
Fabien Maldonado ◽  
Henky Wibowo ◽  
Punit Prakash ◽  
Jan Sebek ◽  
Faraz Chamani ◽  
...  

2016 ◽  
Vol 43 (5) ◽  
pp. 2649-2661 ◽  
Author(s):  
Jan Sebek ◽  
Nathan Albin ◽  
Radoslav Bortel ◽  
Bala Natarajan ◽  
Punit Prakash

Author(s):  
Chandrasekhar Thamire ◽  
Rabee Zuberi ◽  
Charlie Choe ◽  
Prabhakar Pandey

The purpose of this study is to develop thermal-damage correlations for transurethral and interstitial thermotherapy to aid treatment planning for benign prostatic hyperplasia (BPH). Using an Alternating-direction implicit method, the Pennes bioheat transfer equation is solved for microwave and ultrasound hyperthermia applicators for a range of parameters, including the applicator power, treatment time, and coolant parameters. Thermal coagulation contours are developed by evaluating the temperature-history data against the thermal-damage data obtained in ex-vivo experiments for prostate tissue slices and cells. Treatment protocols are proposed for treatment planning purposes and developing an optimal hyperthermia applicator that can coagulate the target tissue effectively, without destroying the surrounding healthy tissue.


Author(s):  
Zhong-Shan Deng ◽  
Jing Liu

The ultimate aim of cryosurgery is to exactly kill all tumor cells within a closely defined region. For this purpose, we recently proposed an effective approach to perform conformal cryosurgical treatment of tumors by adjuvant use of nano-particles. Such a nanoparticle-enabled cryosurgical modality is termed as nano-cryosurgery. In this study, the uncertainties for the predicted temperatures of tissues in nano-cryosurgery due to approximate parameters were investigated. Contributions of uncertainties from the tissue area permeated with nanoparticles, the concentration of nanoparticles, and the thermal parameters of tissues were respectively analyzed, and the uncertainty limits for temperature distributions in these cases were also estimated. The uncertainty analysis presented in this study is expected to serve as a significant guide for performing a highly efficient and also completely safe nano-cryosurgical treatment.


2013 ◽  
Vol 2 (3) ◽  
Author(s):  
Guangxia Hu ◽  
Zhiyu Qian ◽  
Shangwen Ding ◽  
Ye Zhang ◽  
Jieru Xie

Abstract:This paper reports on an effective ablation volume model for microwave ablation of porcine liver. Firstly, in order to obtain the temperature field distribution, a theoretical simulation model of the microwave ablation of porcine liver was developed by solving Pennes bioheat transfer equation using the COMSOL Multiphysics software. Then the effective ablation volume and the effective ablation volume model were obtained using the 1stOpt fitting software by 7D-Soft High Technology Inc. (China). Finally, microwave ablation experiments were carried out using porcine liver to verify the accuracy and effectiveness of the model. The results show that according to the ablation volume model, one can determine the scope of the effective ablation under varying conditions of microwave power and duration. This provides an important basis for the preoperative planning system of microwave ablation.


Author(s):  
Vellavalapalli Satish ◽  
Jatin Kumar ◽  
Ramjee Repaka

Abstract The present article aims to compare the change in the temperature and ablation volume during Microwave ablation procedure. The microwave ablation process is carried out using Fourier and non-Fourier bioheat transfer models in the computational domain of breast tumor. The above models have been considered with the relaxation time known as thermal delay during ablation procedure at constant power and frequency. The above objective has been carried out on a heterogeneous three compartment Breast model using COMSOL-Multiphysics software, with inbuilt bioheat transfer and electromagnetic waves Physics interfaces. The simulation results show that the ablation volume is slightly greater while using Fourier bioheat transfer model as compared to the non-Fourier bioheat transfer model. Further, the temperature distribution also shows that there is a slight variation initially at the start of the ablation, i.e., Fourier heat transfer model shows nearly 2°C more temperature as compared to the non Fourier model and becomes equal as the time increases. The present study helps in establishing the better clinical procedure of Microwave Ablation technique.


2015 ◽  
Author(s):  
Garron Deshazer ◽  
Damian E. Dupuy ◽  
Edward Walsh ◽  
Punit Prakash ◽  
Dillon Fairchild ◽  
...  

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