Mechanical changes of the crystalline lens in oxidative cataractogenesis assessed with optical coherence elastography

Author(s):  
Hongqiu Zhang ◽  
Achuth Nair ◽  
Salavat R. Aglyamov ◽  
Kirill V. Larin
2018 ◽  
Vol 9 (12) ◽  
pp. 6455 ◽  
Author(s):  
Chen Wu ◽  
Salavat R. Aglyamov ◽  
Zhaolong Han ◽  
Manmohan Singh ◽  
Chih-Hao Liu ◽  
...  

Author(s):  
Yogeshwari Ambekar ◽  
Manmohan Singh ◽  
Jitao Zhang ◽  
Achuth Nair ◽  
Salavat R. Aglyamov ◽  
...  

2008 ◽  
Vol 48 (27) ◽  
pp. 2732-2738 ◽  
Author(s):  
Stephen R. Uhlhorn ◽  
David Borja ◽  
Fabrice Manns ◽  
Jean-Marie Parel

2018 ◽  
Vol 59 (2) ◽  
pp. 897 ◽  
Author(s):  
Alberto de Castro ◽  
Antonio Benito ◽  
Silvestre Manzanera ◽  
Juan Mompeán ◽  
Belén Cañizares ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Zhangliang Li ◽  
Ziqi Meng ◽  
Wenyong Qu ◽  
Xiuyuan Li ◽  
Pingjun Chang ◽  
...  

Purpose: To evaluate the effects of age on the morphologies of the crystalline lens, ciliary muscle (CM), Schlemm’s canal (SC), and trabecular meshwork (TM) using swept-source optical coherence tomography (SS-OCT).Methods: Images of the crystalline lens and iridocorneal angle were obtained in healthy participants’ eyes using SS-OCT. Morphological parameters of the crystalline lens, CM, and TM/SC were measured, and the relationship between these parameters and age was evaluated.Results: A total of 62 healthy participants were enrolled, with an age range of 7–79 years. With adjustments for the effects of axial length and sex, both the nasal and temporal SC cross-sectional areas (CSA) and the cross-sectional area of the CM (CMA), distance from the scleral spur to the inner apex of the ciliary muscle (IA-SS), and nasal SC volume were negatively correlated with age (P ≤ 0.041). Meanwhile, the lens thickness (LT) (P < 0.001) and lens vault (LV) (P < 0.001) were positively correlated with age, and the radius of the curvature of the anterior lens (ALR) was negatively correlated with age (P < 0.001).Conclusion: Increasing age was associated with a thicker crystalline lens, a steeper anterior lens curvature, an anteriorly located and smaller CM, and a narrower SC.Clinical Trial Registration:https://register.clinicaltrials.gov/prs/app/action/Select Protocol?sid=S000A3JZ&selectaction=Edit&uid=U00019K7&ts=4&cx=-c5xxp8, identifier [NCT04576884].


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