Coupling of WGM modes of two ZnO microspheres in contact: experiment and simulation

2020 ◽  
Author(s):  
Chia-Liang Liu ◽  
Ching-Hang Chien ◽  
Yia-Chung Chang
Keyword(s):  
Experiment And Simulation ◽  
Contact Experiment

Studies on Metabolism of Urokinase and Mechanism of Thrombolysis by Urokinase

1979 ◽  
Vol 42 (03) ◽  
pp. 885-894 ◽  
Author(s):  
Tatsuo Ueno ◽  
Norio Kobayashi ◽  
Tadashi Maekawa
Keyword(s):  
Molecular Weight ◽  
Plasma Clearance ◽  
Radioactive Material ◽  
Optimal Dosage ◽  
Plasma Clot ◽  
Optimal Dosage Regimen ◽  
Arterial Thrombus ◽  
Contact Experiment

SummaryPharmacokinetics of intravenously injected 125I-labeled urokinase (125I-UK) of a molecular weight of 33,000 daltons in normal rabbits and patients with various diseases were investigated. The plasma clearance of 125I-UK in rabbits was described by a biexponential curve within six hours with a half-life of 8 minutes, 2.3 hours, respectively. The radioactivity in the liver and kidneys 15 minutes after iv injection with 125I-UK was 9.6% and 14.0% of the radioactivity injected, respectively. Approximately 80% of the total radioactive material injected was excreted in the urine in 18 hours. No increase in activator activity in the urine was observed after a large amount of UK injection. Activity uptake of 125I-UK by experimentally induced arterial thrombus was little. Lysis of the stasis thrombus was produced by injecting 7.5 × 104 IU of UK in only one out of 8 rabbits. In vitro contact experiment revealed that transfer of 125I-UK to plasma clot is slow (24 hours for 10% of 125I-UK by plasma clot). In 4 patients plasma clearance of 125I-UK was essentially similar to that in rabbits. From the results obtained optimal dosage regimen of UK administration for complete thrombolysis in vivo was discussed.

Experiment and Simulation of Erosion Behavior and Deformation Characteristics in Al6061-T6 Beam Due to Rhomboid Particle Impacts

2021 ◽  
Vol 69 (3) ◽  
Author(s):  
Mingchao Du ◽  
Zengliang Li ◽  
Xiangwei Dong ◽  
Chunyong Fan ◽  
Jiaqi Che ◽  
...  
Keyword(s):  
Deformation Characteristics ◽  
Erosion Behavior ◽  
Experiment And Simulation
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