In vivo imaging of shock wave-induced nitric oxide generation in the rat cortex (Conference Presentation)

2020 ◽  
Author(s):  
Masaki Inaba ◽  
Satoko Kawauchi ◽  
Takeshi Adachi ◽  
Shunichi Sato ◽  
Izumi Nishidate
Keyword(s):  
Nitric Oxide ◽  
Shock Wave ◽  
In Vivo Imaging ◽  
Rat Cortex ◽  
Wave Induced

Study of underwater shock wave induced embryonic modification in-vivo

2011 ◽  
Author(s):  
Y. Miyamoto ◽  
S.H.R. Hosseini ◽  
D.K. Kang ◽  
Y. Okuda ◽  
D. Oshita ◽  
...  
Keyword(s):  
Shock Wave ◽  
Underwater Shock Wave ◽  
Underwater Shock ◽  
Wave Induced

Activatable photoacoustic and fluorescent probe of nitric oxide for cellular and in vivo imaging

2018 ◽  
Vol 267 ◽  
pp. 403-411 ◽  
Author(s):  
Shichao Wang ◽  
Zhi Li ◽  
Yubin Liu ◽  
Gang Feng ◽  
Jun Zheng ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Fluorescent Probe ◽  
In Vivo Imaging

scholarly journals In vivo imaging of an elicitor-induced nitric oxide burst in tobacco

2000 ◽  
Vol 23 (6) ◽  
pp. 817-824 ◽  
Author(s):  
Ilse Foissner ◽  
David Wendehenne ◽  
Christian Langebartels ◽  
Jorg Durner
Keyword(s):  
Nitric Oxide ◽  
In Vivo Imaging

scholarly journals In vivo imaging of spin-trapped nitric oxide in rats with septic shock: MRI spin trapping

1999 ◽  
Vol 42 (2) ◽  
pp. 235-239 ◽  
Author(s):  
Hirotada Fujii ◽  
Xiaoming Wan ◽  
Jianhui Zhong ◽  
Lawrence J. Berliner ◽  
Kohki Yoshikawa
Keyword(s):  
Nitric Oxide ◽  
Septic Shock ◽  
In Vivo Imaging ◽  
Spin Trapping

scholarly journals Noninvasive assessment of vascular structure and function in conscious rats based on in vivo imaging of the albino iris

2011 ◽  
Vol 300 (6) ◽  
pp. R1333-R1343 ◽  
Author(s):  
Harald M. Stauss ◽  
Kevin R. Rarick ◽  
Katie M. Leick ◽  
Jason W. Burkle ◽  
Diane L. Rotella ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Vascular Disease ◽  
In Vivo Imaging ◽  
Lumen Diameter ◽  
Albino Rats ◽  
Noninvasive Technique ◽  
Spontaneously Hypertensive ◽  
Conscious Rats ◽  
Wistar Kyoto

Experimental techniques allowing longitudinal studies of vascular disease progression or treatment effects are not readily available for most animal models. Thus, most existing studies are destined to either study individual time points or use large cohorts of animals. Here we describe a noninvasive technique for studying vascular disease that is based on in vivo imaging of the long posterior ciliary artery (LPCA) in the iris of albino rats. Using a slit-lamp biomicroscope, images of the LPCA were taken weekly in conscious normotensive Wistar Kyoto rats (WKY, n = 10) and spontaneously hypertensive rats (SHR, n = 10) for 10 wk. Using imaging software, we found that lumen diameter was significantly smaller and the wall-to-lumen (W/L) ratio larger in SHR than in WKY. Wall thickness was not different. Blood pressure correlated with the W/L ratio. Histology of the abdominal aorta also revealed a smaller lumen diameter and greater W/L ratio in SHR compared with WKY. Corneal application of the muscarinic receptor agonist pilocarpine elicited a dose-dependent vasodilation of the LPCA that could be antagonized by inhibition of nitric oxide synthase, suggesting that the pilocarpine response is mainly mediated by endothelium-derived nitric oxide. Consistent with endothelial dysfunction in SHR, pilocarpine-induced vasodilation was greater in WKY rats than in SHR. These findings indicate that in vivo imaging of the LPCA allows assessment of several structural and functional vascular parameters in conscious rats and that the LPCA responds to disease insults and pharmacologic treatments in a fashion that will make it a useful model for further studies.

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