scholarly journals Mid-infrared spectroscopy with a fiber-coupled tuneable quantum cascade laser for glucose sensing

Author(s):  
Ine L. Jernelv ◽  
Karina Strøm ◽  
Dag R. Hjelme ◽  
Astrid Aksnes
2007 ◽  
Vol 91 (23) ◽  
pp. 231101 ◽  
Author(s):  
Benjamin G. Lee ◽  
Mikhail A. Belkin ◽  
Ross Audet ◽  
Jim MacArthur ◽  
Laurent Diehl ◽  
...  

2018 ◽  
Vol 90 (17) ◽  
pp. 10494-10500 ◽  
Author(s):  
Jessica L. Klocke ◽  
Markus Mangold ◽  
Pitt Allmendinger ◽  
Andreas Hugi ◽  
Markus Geiser ◽  
...  

2013 ◽  
Vol 102 (12) ◽  
pp. 121117 ◽  
Author(s):  
I. Galli ◽  
M. Siciliani de Cumis ◽  
F. Cappelli ◽  
S. Bartalini ◽  
D. Mazzotti ◽  
...  

2015 ◽  
Vol 23 (5) ◽  
pp. 5670 ◽  
Author(s):  
Anton Hasenkampf ◽  
Niels Kröger ◽  
Arthur Schönhals ◽  
Wolfgang Petrich ◽  
Annemarie Pucci

2016 ◽  
Vol 70 (9) ◽  
pp. 1511-1519 ◽  
Author(s):  
Nataly J. Galán-Freyle ◽  
Leonardo C. Pacheco-Londoño ◽  
Andrés D. Román-Ospino ◽  
Samuel P. Hernandez-Rivera

Quantum cascade laser spectroscopy was used to quantify active pharmaceutical ingredient content in a model formulation. The analyses were conducted in non-contact mode by mid-infrared diffuse reflectance. Measurements were carried out at a distance of 15 cm, covering the spectral range 1000–1600 cm−1. Calibrations were generated by applying multivariate analysis using partial least squares models. Among the figures of merit of the proposed methodology are the high analytical sensitivity equivalent to 0.05% active pharmaceutical ingredient in the formulation, high repeatability (2.7%), high reproducibility (5.4%), and low limit of detection (1%). The relatively high power of the quantum-cascade-laser-based spectroscopic system resulted in the design of detection and quantification methodologies for pharmaceutical applications with high accuracy and precision that are comparable to those of methodologies based on near-infrared spectroscopy, attenuated total reflection mid-infrared Fourier transform infrared spectroscopy, and Raman spectroscopy.


2016 ◽  
Vol 88 (5) ◽  
pp. 2558-2562 ◽  
Author(s):  
Markus Sieger ◽  
Julian Haas ◽  
Michael Jetter ◽  
Peter Michler ◽  
Matthias Godejohann ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document