Investigation of active matrix-metaloproteinase-8 (aMMP-8) as a reference parameter for path control in antimicrobial photothermal therapy (aPTT) using a split-mouth design

Author(s):  
Jeannette Deumer ◽  
Matthias Frentzen ◽  
Martina C. Meinke
2020 ◽  
Vol 64 (1-4) ◽  
pp. 1495-1504
Author(s):  
Fangchao Xu ◽  
Yongquan Guo ◽  
Ran Zhou ◽  
Junjie Jin ◽  
Chuan Zhao ◽  
...  

To solve the problem of reduction of suspension force of permanent magnet system with variable magnetic flux path control, according to the structure of the system, suspension principle of the permanent magnet system with variable magnetic flux path control and the generation principle of the load torque, the influence of the mechanical structure of the system on the suspension force is analyzed by changing part of parameters of the system structure. The results show that the existence of magnetic isolation plate is the main reason for the decrease of suspension force, the permanent magnet ring can be thickened to 11.91 mm, the annular gap can be reduced to 1 mm, thickness of the “F” shaped magnetizer can be increased to 9 mm to increase the suspension force.


2020 ◽  
Vol 140 (7) ◽  
pp. 364-371
Author(s):  
Kenta Torishima ◽  
Kazuhiro Shimura ◽  
Mitsuhide Sato ◽  
Tsutomu Mizuno

2020 ◽  
Author(s):  
zhihong sun ◽  
Guanjun Deng ◽  
Xinghua Peng ◽  
Xiuli Xu ◽  
Lanlan Liu ◽  
...  

Recently, photothermal-immuno synergistic therapy under mild temperature (~ 45 °C) has got broad interest in cancer treatment. Inhibition the intratumorally HSPs production is the key to accomplish highly efficient and mild photothermal therapy. In this work, we developed biomimetic nanoterminators with mature DCs functions by coating the mature dendritic cell membrane on photothermal nanoagents. As-prepared nanoterminators could automatically locate on T cell in the complex tumor-immune microenvironment and promote the T cells proliferation, activation and cytokine secretion, which could not only inhibit the expression of heat shock proteins to cooperate on highly efficient mild photothermal therapy (~42°C), but also promote tumor apoptosis during the treatment. More importantly, this nanoterminator could serve as vaccine to trigger anti-tumor immune response of the whole body, which would be promising to long-life tumor inhibition and termination.


Author(s):  
Chin-Lung Ting ◽  
Chung-Kuang Wei ◽  
Li-Wei Mau ◽  
Ker-Yih Kao ◽  
Ho-Tien Chen ◽  
...  
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