Measurement of fetal cerebral blood flow of the lamb fetus in utero

2019 ◽  
Author(s):  
Giuseppe Lo Presti ◽  
Lorenzo Cortese ◽  
Sergio Berdún ◽  
Elisenda Eixarch ◽  
Eduard Gratacós ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
In Utero

Cerebral blood flow, oxygen consumption, and glucose utilization of fetal lambs in utero

1972 ◽  
Vol 114 (3) ◽  
pp. 292-303 ◽  
Author(s):  
Edgar L. Makowski ◽  
Jack M. Schneider ◽  
Nicholas G. Tsoulos ◽  
James R. Colwill ◽  
Frederick C. Battaglia ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Oxygen Consumption ◽  
Glucose Utilization ◽  
In Utero

Altered Resting Cerebral Blood Flow in Adolescents With in Utero Cocaine Exposure Revealed by Perfusion Functional MRI

PEDIATRICS ◽  
2007 ◽  
Vol 120 (5) ◽  
pp. e1245-e1254 ◽  
Author(s):  
H. Rao ◽  
J. Wang ◽  
J. Giannetta ◽  
M. Korczykowski ◽  
D. Shera ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Functional Mri ◽  
In Utero ◽  
Cocaine Exposure

Effect of Halothane on Regional Cerebral Blood Flow and Cerebral Metabolic Oxygen Consumption in the Fetal Lamb In Utero

1987 ◽  
Vol 67 (3) ◽  
pp. 361-366 ◽  
Author(s):  
D. B. C. Cheek ◽  
S. C. Hughes ◽  
P. A. Dailey ◽  
D. R. Field ◽  
S. Pytka ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Oxygen Consumption ◽  
Regional Cerebral Blood Flow ◽  
In Utero ◽  
Regional Cerebral Blood ◽  
Fetal Lamb

Cerebral blood flow, oxygenation, and carbohydrate metabolism in immature fetal sheep in utero

1989 ◽  
Vol 256 (6) ◽  
pp. R1264-R1268 ◽  
Author(s):  
C. A. Gleason ◽  
C. Hamm ◽  
M. D. Jones
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Glucose Uptake ◽  
Vena Cava ◽  
Lactate Production ◽  
Glucose Consumption ◽  
In Utero ◽  
Fetal Sheep ◽  
O2 Extraction ◽  
Near Term

Studies of cerebral blood flow (CBF) and metabolism in fetal sheep have been largely confined to late gestation, a time when brain development in this species is largely complete. Few studies have been done at a time when the fetal sheep brain is in the midst of rapid differentiation and development. We studied seven fetal sheep in utero at 91 days of gestation (term = 145-150 days) 24 h after catheters were placed into the sagittal sinus, axillary artery, and inferior vena cava. We measured CBF by the microsphere method and used arteriovenous differences of O2, lactate, and glucose to calculate cerebral O2 consumption (CMRo2), fractional O2 extraction, glucose consumption, O2-glucose index (OGI), and cerebral lactate production. Compared with near-term fetal sheep, we found lower CBF (33.9 +/- 5.3 ml.100 g-1.min-1), lower glucose consumption (8.5 +/- 1.25 mumol.100 g-1.min-1), and lower CMRo2 (41.8 +/- 8.8 mumol.100 g-1.min-1). Fractional O2 extraction was 0.29 +/- 0.04, which is similar to near-term fetal sheep. There was consistent cerebral lactate production (2.45 +/- 1.58 mumol.100 g-1.min-1). The OGI was 81 +/- 16%, i.e., oxidative metabolism could account for 81% of glucose uptake. Lactate production accounts for virtually all glucose uptake exceeding that required for oxidation.

Cerebral blood flow response to hypercapnia in immature fetal sheep

1991 ◽  
Vol 261 (5) ◽  
pp. H1366-H1370 ◽  
Author(s):  
S. M. Helou ◽  
M. L. Hudak ◽  
M. D. Jones
Keyword(s):  
Carbon Dioxide ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Axillary Artery ◽  
Vena Cava ◽  
In Utero ◽  
Carbon Dioxide Tension ◽  
Fetal Sheep ◽  
Sagittal Sinus ◽  
The Difference

We have reported recently that the cerebral blood flow (CBF) response to isocapnic hypoxic hypoxia is blunted in fetal sheep in utero at 93 days of gestation (term = 145-150 days), a time of rapid brain differentiation in this species. Cerebral O2 transport fell rather than being maintained, as it is in more mature fetuses. The reason for the blunted response was not clear. We hypothesized that the CBF response to hypercapnia also might be blunted. We studied 10 immature fetal sheep in utero at a mean gestational age of 92 days 24 h after catheters were placed into the superior sagittal sinus, axillary artery, and inferior vena cava. We raised the fetal arterial carbon dioxide tension (PaCO2) by changing the mother's inspired PCO2. CBF was measured before and during hypercapnia by the microsphere method. The overall increase in CBF in response to hypercapnia in immature fetuses was lower than in near-term fetuses. However, the difference was eliminated after correcting for differences in cerebral O2 consumption. This study failed to show any defect in the ability of cerebral vessels in immature fetal sheep to respond to carbon dioxide.

Alterations in regional decreased cerebral blood flow in patients with irritable bowel syndrome-A PET imaging study

2001 ◽  
Vol 120 (5) ◽  
pp. A637-A637
Author(s):  
Y RINGEL ◽  
D DROSSMAN ◽  
T TURKINGTON ◽  
B BRADSHAW ◽  
R COLEMAN ◽  
...  
Keyword(s):  
Blood Flow ◽  
Irritable Bowel Syndrome ◽  
Cerebral Blood Flow ◽  
Pet Imaging ◽  
Imaging Study ◽  
Irritable Bowel
Sign in / Sign up

Export Citation Format

Share Document