A novel multimodal optical imaging device for cervical cancer screening and diagnosis

Author(s):  
Shiri Gordon ◽  
Oz Seadia ◽  
Effi Levi ◽  
Ilan Landesman
2020 ◽  
Vol 6 (Supplement_1) ◽  
pp. 50-50
Author(s):  
Mary Elizabeth Dotson ◽  
Mercy Asiedu ◽  
Nimmi Ramanujam

PURPOSE Invasive cervical cancer is preventable, yet it affects 500,000 women worldwide each year, and more than one half these women die. Barriers to cervical cancer screening include a lack of awareness of cervical cancer and the cervix, fear of the speculum, and lack of women-centric technologies. We developed a low-cost (approximately $50), cervix-imaging device called the Callascope, which consists of an imaging component, camera, and inserter that obviates the need for a speculum and enables self-insertion. Studies are lacking regarding women’s willingness to independently image their cervix and women’s ability to effectively use the Callascope for self-imaging. METHODS We conducted two studies: in-depth interviews to assess the willingness to self-image the cervix, perceptions of the Callascope, and knowledge, attitudes, and practices toward cervical cancer screening; and home-based self-cervix imaging with the Callascope where women recorded an audio reflection on their experience. RESULTS Participants in interviews (n = 12) and home study (n = 12) all indicated a preference for the Callascope over the speculum. Interview data demonstrated that 53% of participants had little knowledge of basic reproductive anatomy, and only 17% of participants understood that human papillomavirus was a direct cause of cervical cancer. Self-exam data showed that 83% of participants were able to visualize their cervix with the Callascope on the first try and 100% were able to do so by the end of the study. Of participants, 100% indicated that the home exam was an empowering and informative experience. CONCLUSION The Callascope is more comfortable than the speculum and women are able to successfully image their cervices from home without the need for a speculum. With improved diagnostic capabilities, the Callascope could be used by medical providers for clinical exams, particularly in low-resource settings, as a low-cost and more comfortable alternative to the SOC. The Callascope enables home self-screening for cervical cancer and a better understanding of one’s body, which could make screening more accessible in low-resource settings.


PLoS ONE ◽  
2018 ◽  
Vol 13 (2) ◽  
pp. e0192530 ◽  
Author(s):  
Christopher T. Lam ◽  
Jenna Mueller ◽  
Betsy Asma ◽  
Mercy Asiedu ◽  
Marlee S. Krieger ◽  
...  

2016 ◽  
Vol 19 (3) ◽  
pp. A143
Author(s):  
Y Wang ◽  
C Li ◽  
J Chen ◽  
Y Wen ◽  
X Pan ◽  
...  

2019 ◽  
Author(s):  
Mercy N. Asiedu ◽  
Júlia S. Agudogo ◽  
Mary Elizabeth Dotson ◽  
Marlee S. Krieger ◽  
John W. Schmitt ◽  
...  

AbstractBackgroundInvasive cervical cancer is preventable, yet affects 500,000 women worldwide each year, and over half these women die. Barriers to cervical cancer screening include lack of awareness of cervical cancer and the cervix, fear of the speculum, and lack of women-centric technologies. We developed a low-cost (∼$50), cervix-imaging device called the Callascope, which comprises an imaging component, camera and inserter that eliminates the need for a speculum and enables self-insertion. We sought to assess the quality of physicians’ images of the cervix using the Callascope versus the speculum in live patients and study women’s willingness to independently use the Callascope to image their cervix.MethodsWe conducted two main studies: (1) a clinical study in which a physician imaged the cervix of patients using both the speculum and Callascope in a 2×2 crossover design; and (2) home-based self-cervix imaging with the Callascope.ResultsParticipants of the clinical study (n=28) and home study (n=12) all indicated greater comfort and an overall preference for the Callascope over the speculum. The clinical study data indicated that the Callascope enabled similar visualization compared to the speculum while significantly improving patient experience. With physician insertion and manipulation, the Callascope enabled cervix visualization for 82% of participants. In the home-study, 83% of participants were able to visualize their cervix with the Callascope on the first try and 100% after multiple attempts.ConclusionThe Callascope is more comfortable and provides similar visualization to the speculum. The Callascope can be used by medical providers for clinical exams while also enabling home self-screening for cervical cancer and promoting a better understanding of one’s cervix to increase awareness of cervical screening needs. The Callascope may increase cervical cancer screening rates through reducing barriers including cost, discomfort, lack of awareness and stigma.


2021 ◽  
Author(s):  
Michael Herriges ◽  
Ruben Pinkhasov ◽  
Keren Lehavot ◽  
Oleg Shapiro ◽  
Joseph M. Jacob ◽  
...  

Abstract PurposeData on heterogeneity in cancer screening and diagnosis rates among lesbians/gays and bisexuals (LGBs) is lacking. Recent studies showed that LGBs have decreased healthcare utilization compared to heterosexual counterparts. Few studies have examined how sexual orientation impacts cancer screening and prevalence. We, therefore, investigated the association between sexual orientation and prevalent sex-specific cancer including prostate (PCa), breast (BC), and cervical (CC) cancer.MethodsThis was a cross-sectional survey-based US study, including men and women aged 18+ from the Health Information National Trends Survey (HINTS) database between 2017-2019. The primary endpoint was individual-reported prostate, breast, and cervical cancer screening and prevalence rates among heterosexual and LGB men and women. Multivariable logistic regression analyses assessed association of various covariates with undergoing screening and diagnosis of these cancers.ResultsOverall, 4,441 and 6,333 heterosexual men and women, respectively, were compared to 225 and 213 LGB men and women, respectively. LGBs were younger and less likely to be screened for PCa, BC, and CC than heterosexuals. A higher proportion of heterosexual women than lesbian and bisexual women were screened for CC with pap smears (95.36% vs. 90.48% and 86.11%, p=<0.001) and BC with mammograms (80.74% vs. 63.81% and 45.37%, p=<0.001). Similarly, a higher proportion of heterosexual men than gay and bisexual men were screened for PCa with PSA blood tests (41.27% vs. 30.53% and 27.58%, p=<0.001). ConclusionThere were more heterosexuals than LGBs screened for CC, BC, and PCa. Healthcare professionals should be encouraged to improve cancer screening among LGBs.


2016 ◽  
pp. 345-375 ◽  
Author(s):  
Haq Nawaz ◽  
Nosheen Rashid ◽  
Hugh Byrne ◽  
Fiona Lyng

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