Functional retinal imaging using adaptive optics swept-source OCT at 1.6 MHz (Conference Presentation)

Author(s):  
Mehdi Azimipour ◽  
Justin V. Migacz ◽  
Robert J. Zawadzki ◽  
John S. Werner ◽  
Ravi S. Jonnal
Optica ◽  
2019 ◽  
Vol 6 (3) ◽  
pp. 300 ◽  
Author(s):  
Mehdi Azimipour ◽  
Justin V. Migacz ◽  
Robert J. Zawadzki ◽  
John S. Werner ◽  
Ravi S. Jonnal

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Yifan Jian ◽  
Sujin Lee ◽  
Myeong Jin Ju ◽  
Morgan Heisler ◽  
Weiguang Ding ◽  
...  

2016 ◽  
Author(s):  
Yifan Jian ◽  
Sujin Lee ◽  
Michelle Cua ◽  
Dongkai Miao ◽  
Stefano Bonora ◽  
...  

2015 ◽  
Author(s):  
Daniel J. Fechtig ◽  
Abhishek Kumar ◽  
Laurin Ginner ◽  
Wolfgang Drexler ◽  
Rainer A. Leitgeb

2020 ◽  
pp. bjophthalmol-2020-316111 ◽  
Author(s):  
Xinwen Yao ◽  
Mengyuan Ke ◽  
Yijie Ho ◽  
Emily Lin ◽  
Damon W K Wong ◽  
...  

Background/imsTo compare the retinal vessel diameter measurements obtained from the swept-source optical coherence tomography angiography (OCTA; Plex Elite 9000, Carl Zeiss Meditec, USA) and adaptive optics ophthalmoscope (AOO; RTX1, Imagine Eyes, France).MethodsFifteen healthy subjects, 67% women, mean age (SD) 30.87 (6.19) years, were imaged using OCTA and AOO by a single experienced operator on the same day. Each eye was scanned using two OCTA protocols (3×3 mm2 and 9×9 mm2) and two to five AOO scans (1.2×1.2 mm2). The OCTA and AOO scans were scaled to the same pixel resolution. Two independent graders measured the vessel diameter at the same location on the region-of-interest in the three coregistered scans. Differences in vessel diameter measurements between the scans were assessed.ResultsThe inter-rater agreement was excellent for vessel diameter measurement in both OCTA protocols (ICC=0.92) and AOO (ICC=0.98). The measured vessel diameter was widest from the OCTA 3×3 mm2 (55.2±16.3 µm), followed by OCTA 9×9 mm2 (54.7±14.3 µm) and narrowest by the AOO (50.5±15.6 µm; p<0.001). Measurements obtained from both OCTA protocols were significantly wider than the AOO scan (OCTA 3×3 mm2: mean difference Δ=4.7 µm, p<0.001; OCTA 9×9 mm2: Δ=4.2 µm, p<0.001). For vessels >45 µm, it appeared to be larger in OCTA 3×3 mm2 scan than the 9×9 mm2 scan (Δ=1.9 µm; p=0.005), while vessels <45 µm appeared smaller in OCTA 3×3 mm2 scan (Δ=−1.3 µm; p=0.009)ConclusionsThe diameter of retinal vessels measured from OCTA scans were generally wider than that obtained from AOO scans. Different OCTA scan protocols may affect the vessel diameter measurements. This needs to be considered when OCTA measures such as vessel density are calculated.


2021 ◽  
Vol 12 (3) ◽  
pp. 1577
Author(s):  
Abhishek Kumar ◽  
Stefan Georgiev ◽  
Matthias Salas ◽  
Rainer A. Leitgeb

Author(s):  
Simrat K. Sodhi ◽  
John Golding ◽  
Carmelina Trimboli ◽  
Netan Choudhry

Abstract Purpose To describe the feasibility of peripheral OCT imaging in retinal diseases using a novel full-field device. Methods A total of 134 consecutive eyes were referred and imaged on the Optos Silverstone swept-source OCT (SS-OCT) (Optos PLC; Dunfermline, UK). Scanning laser ophthalmoscope (SLO) images and the associated SS-OCT images were obtained in the posterior pole, mid-periphery or far periphery based on the nature of the referral and on new areas of interest observed in the optomap images at the time of imaging. Results A total of 134 eyes (96 patients) were enrolled in the study. One hundred and twenty-five eyes (91 patients) with 38 retinal pathologies were prospectively assessed and 9 eyes (5 patients) were excluded due to incomplete image acquisition. The average age of the subjects was 54 years (range 21–92 years). Thirty-nine out of 125 eyes (31%) had macular pathologies. Eighty-six out of 125 eyes (69%) had peripheral only pathologies, an area which cannot be visualized by standard OCT devices with a 50 degree field-of-view. Conclusions The ability to capture peripheral pathologies using an integrated SLO-UWF imaging with full-field swept-source provided high-grade anatomical insight that confirmed the medical and surgical management in a majority of cases. Its use in the mid- and far periphery provides a holistic clinical picture, which can potentially aid in the understanding of various retinal pathologies.


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