Design of fiber bundle imaging system

Author(s):  
Jun Chang ◽  
Kaiyuan Fan ◽  
Lingjie Wang ◽  
Guangwei Shi ◽  
Hongbo Wu ◽  
...  
Keyword(s):  
2010 ◽  
Author(s):  
Gang Wang ◽  
Jianlin Li ◽  
Xinbo Zheng ◽  
Zhonghua Fang

2015 ◽  
Vol 86 (5) ◽  
pp. 053505 ◽  
Author(s):  
B. Chektybayev ◽  
G. Shapovalov ◽  
A. Kolodeshnikov

2012 ◽  
Vol 51 (29) ◽  
pp. 6913 ◽  
Author(s):  
Chenhui Huang ◽  
Saiko Kino ◽  
Takashi Katagiri ◽  
Yuji Matsuura

2016 ◽  
Author(s):  
Xingtao Yan ◽  
Fu Li ◽  
Xiaolong Ma ◽  
Juan Lv ◽  
Yinghong He ◽  
...  

Micromachines ◽  
2019 ◽  
Vol 10 (12) ◽  
pp. 820
Author(s):  
He Leng ◽  
Yuhling Wang ◽  
De-Fu Jhang ◽  
Tsung-Sheng Chu ◽  
Chia-Hui Tsao ◽  
...  

Photoacoustic (PA) imaging is an attractive technology for imaging biological tissues because it can capture both functional and structural information with satisfactory spatial resolution. Current commercially available PA imaging systems are limited by their bulky size or inflexible user interface. We present a new handheld real-time ultrasound/photoacoustic imaging system (HARP) consisting of a detachable, high-numerical-aperture (NA) fiber bundle-based illumination system integrated with an array-based ultrasound (US) transducer and a data acquisition platform. In this system, different PA probes can be used for different imaging applications by switching the transducers and the corresponding jackets to combine the fiber pads and transducer into a single probe. The intuitive user interface is a completely programmable MATLAB-based platform. In vitro phantom experiments were conducted to test the imaging performance of the developed PA system. Furthermore, we demonstrated (1) in vivo brain vasculature imaging, (2) in vivo imaging of real-time stimulus-evoked cortical hemodynamic changes during forepaw electrical stimulation, and (3) in vivo imaging of real-time cerebral pharmacokinetics in rats using the developed PA system. The overall purpose of this design concept for a customizable US/PA imaging system is to help overcome the diverse challenges faced by medical researchers performing both preclinical and clinical PA studies.


Author(s):  
Willem H.J. Andersen

Electron microscope design, and particularly the design of the imaging system, has reached a high degree of perfection. Present objective lenses perform up to their theoretical limit, while the whole imaging system, consisting of three or four lenses, provides very wide ranges of magnification and diffraction camera length with virtually no distortion of the image. Evolution of the electron microscope in to a routine research tool in which objects of steadily increasing thickness are investigated, has made it necessary for the designer to pay special attention to the chromatic aberrations of the magnification system (as distinct from the chromatic aberration of the objective lens). These chromatic aberrations cause edge un-sharpness of the image due to electrons which have suffered energy losses in the object.There exist two kinds of chromatic aberration of the magnification system; the chromatic change of magnification, characterized by the coefficient Cm, and the chromatic change of rotation given by Cp.


Author(s):  
G. Botton ◽  
G. L’Espérance ◽  
M.D. Ball ◽  
C.E. Gallerneault

The recently developed parallel electron energy loss spectrometers (PEELS) have led to a significant reduction in spectrum acquisition time making EELS more useful in many applications in material science. Dwell times as short as 50 msec per spectrum with a PEELS coupled to a scanning transmission electron microscope (STEM), can make quantitative EEL images accessible. These images would present distribution of elements with the high spatial resolution inherent to EELS. The aim of this paper is to briefly investigate the effect of acquisition time per pixel on the signal to noise ratio (SNR), the effect of thickness variation and crystallography and finally the energy stability of spectra when acquired in the scanning mode during long periods of time.The configuration of the imaging system is the following: a Gatan PEELS is coupled to a CM30 (TEM/STEM) electron microscope, the control of the spectrometer and microscope is performed through a LINK AN10-85S MCA which is interfaced to a IBM RT 125 (running under AIX) via a DR11W line.


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