Charge cluster identification for multidimensional GEM detector structures

2018 ◽  
Author(s):  
Tomasz Czarski ◽  
Maryna Chernyshova ◽  
Karol Malinowski ◽  
Pawel Linczuk ◽  
Ewa Kowalska-Strzeciwilk ◽  
...  
Keyword(s):  
Cluster Identification ◽  
Charge Cluster ◽  
Gem Detector

Dimensionality Reduction for Cluster Identification in Metagenomics using Autoencoders

2020 ◽  
Author(s):  
Uditha Maduranga ◽  
Kalana Wijegunarathna ◽  
Sadeep Weerasinghe ◽  
Indika Perera ◽  
Anuradha Wickramarachchi
Keyword(s):  
Dimensionality Reduction ◽  
Cluster Identification

scholarly journals Small-Scale Coastal Fisheries in the Midst of Adaptation and Diversification: Insights from Southern Italy

2021 ◽  
Vol 13 (13) ◽  
pp. 7393
Author(s):  
Agata Nicolosi ◽  
Donatella Di Gregorio ◽  
Giuseppe Arena ◽  
Valentina Rosa Laganà ◽  
Donatella Privitera
Keyword(s):  
Southern Italy ◽  
Multiple Correspondence Analysis ◽  
Marketing Strategies ◽  
Small Scale ◽  
Artisanal Fishing ◽  
Economic Activities ◽  
Coastal Fisheries ◽  
Cluster Identification ◽  
The Eu

The study looks at the problems facing coastal fishing communities. It highlights the impacts that, in the complex framework of the EU reforms, have manifested themselves on economic activities and on society. The aim of the paper is twofold: to examine small-scale artisanal fishing in an area of Southern Italy in order to develop resilience and diversification and at the same time to outline the profiles of local bluefish buyers to highlight development strategies for the sector. The research carried out through a direct survey by administering a questionnaire to fishermen operating in areas of Southern Italy and the data cross-referenced with the opinions of local consumers. A conjoint experiment, followed by a multiple correspondence analysis and cluster identification, was used to outline the profiles of local bluefish buyers. The results of the analysis reveal that the fish market and the restaurant sector are the main distribution channels preferred by fishermen. Furthermore, fishermen are very sensitive to environmental issues and are willing to collaborate and actively participate in the environmental protection of the sea. Consumers recognise the quality of local bluefish, and they implicitly perceive the sustainability of the method of capture. The results show the need to undertake synergistic actions for the fishing industry, capable of activating marketing strategies adequately to support, promote and develop the sector. The results of the study provide helpful information for food companies in order to better segment their market and target their consumers, as well as to effectively promote their product using brands, certifications and traceability.

GEMINI: A triple-GEM detector read-out mixed-signal ASIC in 180nm CMOS

2015 ◽  
Author(s):  
A. Pezzotta ◽  
G. Corradi ◽  
G. Croci ◽  
M. De Matteis ◽  
F. Murtas ◽  
...  
Keyword(s):  
Mixed Signal ◽  
Gem Detector

scholarly journals Mutational Mapping of UL130 of Human Cytomegalovirus Defines Peptide Motifs within the C-Terminal Third as Essential for Endothelial Cell Infection

2010 ◽  
Vol 84 (18) ◽  
pp. 9019-9026 ◽  
Author(s):  
Andrea Schuessler ◽  
Kerstin Laib Sampaio ◽  
Laura Scrivano ◽  
Christian Sinzger
Keyword(s):  
Endothelial Cell ◽  
Human Cytomegalovirus ◽  
Artificial Chromosome ◽  
Protein Domain ◽  
Cell Infection ◽  
Peptide Motifs ◽  
Charged Amino Acids ◽  
C Terminus ◽  
Charge Cluster ◽  
A Charge

ABSTRACT The UL130 gene is one of the major determinants of endothelial cell (EC) tropism of human cytomegalovirus (HCMV). In order to define functionally important peptides within this protein, we have performed a charge-cluster-to-alanine (CCTA) mutational scanning of UL130 in the genetic background of a bacterial artificial chromosome-cloned endotheliotropic HCMV strain. A total of 10 charge clusters were defined, and in each of them two or three charged amino acids were replaced with alanines. While the six N-terminal clusters were phenotypically irrelevant, mutation of the four C-terminal clusters each caused a reduction of EC tropism. The importance of this protein domain was further emphasized by the fact that the C-terminal pentapeptide PNLIV was essential for infection of ECs, and the cell tropism could not be rescued by a scrambled version of this sequence. We conclude that the C terminus of the UL130 protein serves an important function for infection of ECs by HCMV. This makes UL130 a promising molecular target for antiviral strategies, e.g., the development of antiviral peptides.

scholarly journals Development of a scintillating G-GEM detector for a 6-MeV X-band Linac for medical applications

2013 ◽  
Vol 8 (12) ◽  
pp. C12020-C12020 ◽  
Author(s):  
T Fujiwara ◽  
S Tanaka ◽  
Y Mitsuya ◽  
H Takahashi ◽  
K Tagi ◽  
...  
Keyword(s):  
Medical Applications ◽  
X Band ◽  
Gem Detector
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