Investigation of mixed saliva by optoelectronic methods

Author(s):  
Elina Nepomnyashchaya ◽  
Elena Velichko ◽  
Tatyana Bogomaz ◽  
Maksim Baranov ◽  
Evgenii Aksenov ◽  
...  
Keyword(s):  
1992 ◽  
Vol 35 (1-2) ◽  
pp. 29-33 ◽  
Author(s):  
Joyce W. Jenzano ◽  
Susan L. Hogan ◽  
R. L. Lundblad
Keyword(s):  

PEDIATRICS ◽  
1958 ◽  
Vol 22 (5) ◽  
pp. 945-952
Author(s):  
Giulio J. Barbero ◽  
Warren Chernick

A significantly greater rate of "unstimulated" parotid salivary flow was observed with 14 children with cystic fibrosis of the pancreas than with 24 normal children. The concentration of sodium and chloride in mixed saliva was significantly elevated in 12 children with cystic fibrosis of the pancreas as compared with 14 normal children. The response to injection of methacholine chloride was greater for both rate of parotid flow and concentration of sodium and chloride with 10 children with cystic fibrosis of the pancreas than with 10 normal children. Concentration of potassium showed no significant difference in either group. The response elicited in the parotid by administration of methacholine chloride indicated a decreased threshold of response and consequent increased sensitivity to parasympathomimetic stimulation in the patients with cystic fibrosis of the pancreas.


1956 ◽  
Vol 9 (1) ◽  
pp. 79-81 ◽  
Author(s):  
Leon H. Schneyer
Keyword(s):  

2018 ◽  
Vol 99 (4) ◽  
pp. 593-597
Author(s):  
S Z Aliev

Aim. Study of the main cytokines (interleukin-1β and -2, interferon γ) in the mixed saliva from patients with chronic sialadenitis on the basic and comprehensive treatment dynamically. Methods. During the period of 2014 to 2017 we performed examination and treatment of patients with salivary gland diseases. Out of them we defined a group with chronic non-specific sialadenitis including 45 patients seen in the clinic in exacerbation. Patients in the comparison group received basic treatment. Patients in the study group additionally to conventional treatment were administered local immunotherapy. Measurement of cytokine levels in the oral fluid was performed in 45 patients with chronic sialadenitis in exacerbation and in 10 practically healthy subjects. Results. The level of interleukin-1β in saliva was found to be significantly increased before treatment (p <0.05). After the treatment interleukin-1β level in saliva decreased in both groups but most significantly this parameter decreased in the study group. After including local immunocorrection into the treatment complex dynamic decrease of interleukin-2 to 14.7±0.4 pg/ml was registered, which apparently is associated with stabilization of immune processes in the oral cavity. After the treatment conducted according to traditional scheme in the comparison group the level of interferon γ in saliva increased to 7.2±0.2 pg/ml which is 1.1 times higher than before treatment. Conclusion. In patients with chronic sialadenitis in exacerbation the level of interleukin-1β statistically significantly increases by 1. times (p <0.05), interleukin 2 - by 2.1 times (p <0.05) and the level of interferon γ decreases by 1.4 times (p <0.05) which is indicative of immunological signs of inflammatory reaction; use of local immunocorrection leads to more prominent decrease of interleukin-1β (by 20.3 vs 16.2% in comparison group; p <0.05), interleukin-2 (by 38.8 vs 26.6%; p <0.05) and increase of interferon γ (by 21.2 vs 12.5% in comparison group; p <0.05).


1988 ◽  
Vol 119 (1) ◽  
pp. 56-60 ◽  
Author(s):  
F. W. Chu ◽  
R. P. Ekins

Abstract. Corticosteroid binding globulin (CBG) was detected by a specific radioimmunoassay in mixed saliva (25.4 ± 4.0 μg/l, mean ± sem) and in pure, uncontaminated parotid fluids (17.4 ± 2.7 μg/l) at resting flowrates of approximately 500 μl/min and 50 μl/gland per min, respectively. In parotid fluids collected at stimulated flow-rates of between 300–1000 μl/gland per min, CBG could not be detected. This observation suggests the direct flow-rate-dependent transfer/secretion of CBG in saliva. When cortisol was measured (RIA) in dilution experiments in both mixed saliva and parotid fluids using phosphate buffer at pH 7.4 as diluent, a protein-binding effect analogous to that found in plasma samples was observed. However, this effect was abolished if a known CBG inhibitor, phosphate:citrate buffer at pH 4, was used as the diluent in the assay. A bound fraction of cortisol was found in both mixed saliva (14.0 ± 4.0%) and parotid fluid samples (12.3 ± 1.3%) by equilibrium dialysis. These findings appear to contradict the currently accepted notion that specific plasma steroid binding proteins, and hence the protein-bound steroids, are absent in uncontaminated saliva; and that their presence in mixed saliva is the consequence solely of contamination by gingival fluid and/or plasma from mouth or gum abrasions. We conclude that both protein-bound and free steroids are present in uncontaminated saliva and that salivary total and plasma free steroid concentrations are not identical.


1994 ◽  
Vol 73 (2) ◽  
pp. 544-555 ◽  
Author(s):  
E.L. Thomas ◽  
M.M. Jefferson ◽  
R.E. Joyner ◽  
G.S. Cook ◽  
C.C. King
Keyword(s):  

1962 ◽  
Vol 13 (5) ◽  
pp. 907 ◽  
Author(s):  
WR McManus

Seven in vivo experiments are reported in which the effects of diverting alkaline mixed saliva from the actively fermenting contents of the rumen of anaesthetized and conscious sheep fed on a standard ration were studied for periods up to 6 hr. The absence of various quantities of saliva (225–1349 ml) was associated with profound alterations in the rumen environment: rumen liquor volatile fatty acid (V.F.A.) levels were consistently and substantially elevated, and rumen pH levels depressed. These changes in the rumen environment began about 40–60 min after saliva diversion commenced, and were sustained long after such values for the control animals had inflected towards fasting levels. Rumen movements were recorded in two experiments. Rumen movement was reduced, but not entirely suppressed, some 60 min after the minimal pH values obtained. It is suggested that this reduction in rumen movement was a consequence of depressed pH values. The rumen pH-rumen V.F.A. relationship was, in six such cases, altered but the strength of this relationship was not significantly changed. It was concluded that these effects on rumen pH-V.F.A. levels and relationship were due, directly or indirectly, to the changed buffering or osmotic regime, or both, of the saliva-depleted rumen liquor. Implications of these findings are discussed in the light of rumen physiology and the field use of oesophageally fistulated sheep.


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