Photodynamic therapy of human malignant tumors: a comparative study between photohem and tetrasulfonated aluminum phthalocyanine

Author(s):  
Eugeny P. Stranadko ◽  
Oleg K. Skobelkin ◽  
Grigory D. Litvin ◽  
Tamara A. Astrakhankina
Author(s):  
Chiara Cortelazzi ◽  
Giulia Odorici ◽  
Elisa Castagnetti ◽  
Giovanni Pellacani ◽  
Sergio Di Nuzzo

1989 ◽  
Vol 30 (5) ◽  
pp. 277-282 ◽  
Author(s):  
Duan-Ren Wen ◽  
Dave SB Hoon ◽  
Cindy Chang ◽  
Alistair J. Cochran

2016 ◽  
Vol 38 (2) ◽  
pp. 427-448 ◽  
Author(s):  
Yanping Gao ◽  
Bing Feng ◽  
Siqi Han ◽  
Kai Zhang ◽  
Jing Chen ◽  
...  

Cancer remains one of the most threatening causes of human health impairment, and the mechanisms underlying tumorigenesis have not been completely characterized. MicroRNAs (miRNAs) are a group of endogenous, small (18∼25 nucleotides) non-coding RNAs which negatively regulate gene expressions by directly binding to the 3'-untranslated regions (3'-UTRs) of the target messenger RNAs (mRNAs). Increasing evidence has demonstrated abnormal miRNA profiles and confirmed their involvement in tumor initiation and progression. As one important member of the miR-200 family, microRNA (miR)-141 is aberrantly expressed in many human malignant tumors, participating in various cellular processes including epithelial-mesenchymal transition (EMT), proliferation, migration, invasion, and drug resistance. In the present review, we briefly describe the mechanisms underlying miR-141-mediated tumorigenesis and the possible future of miR-141 as a potential diagnostic and prognostic parameter as well as therapeutic target in clinical applications.


Sign in / Sign up

Export Citation Format

Share Document