scholarly journals Kapton polyimide-based EEG microelectrode array and interfaces for mice brainwave recordings and analysis

2018 ◽  
Author(s):  
Mohammad M. Islam ◽  
Deepa Gupta ◽  
Hyungwoo Nam ◽  
Mary Kay Lobo ◽  
Fow-Sen Choa
Keyword(s):  
Microelectrode Array

Piezo-Driven Vibrating Insertion Device for Microelectrode Array

2009 ◽  
Vol 129 (1) ◽  
pp. 25-31
Author(s):  
Takahiro Noda ◽  
Ryohei Kanzaki ◽  
Hirokazu Takahashi
Keyword(s):  
Microelectrode Array ◽  
Insertion Device

Single Cell Based Microelectrode Array Biosensors

2003 ◽  
Vol 773 ◽  
Author(s):  
Mo Yang ◽  
Shalini Prasad ◽  
Xuan Zhang ◽  
Mihrimah Ozkan ◽  
Cengiz S. Ozkan
Keyword(s):  
Electrical Activity ◽  
Single Cell ◽  
Cellular Response ◽  
Microelectrode Array ◽  
Fast Fourier Transformation ◽  
Chemical Agent ◽  
Extracellular Potential ◽  
Membrane Excitability ◽  
Specific Chemical ◽  
Chemical Agents

AbstractExtracellular potential is an important parameter which indicates the electrical activity of live cells. Membrane excitability in osteoblasts plays a key role in modulating the electrical activity in the presence of chemical agents. The complexity of cell signal makes interpretation of the cellular response to a chemical agent very difficult. By analyzing shifts in the signal power spectrum, it is possible to determine a frequency spectrum also known as Signature Pattern Vectors (SPV) specific to a chemical. It is also essential to characterize single cell sensitivity and response time for specific chemical agents for developing detect-to-warn biosensors. We used a 4x4 multiple Pt microelectrode array to spatially position single osteoblast cells, by using a gradient AC field. Fast Fourier Transformation (FFT) and Wavelet Transformation (WT) analyses were used to extract information pertaining to the frequency of firing from the extracellular potential.

Study of Liposome Electrofusion on Microelectrode Array Chip

2013 ◽  
Vol 40 (4) ◽  
pp. 551-555
Author(s):  
Feng JIANG ◽  
Jun YANG ◽  
Zhen-Yu WANG ◽  
Ning HU ◽  
Xiao-Lin ZHENG ◽  
...  
Keyword(s):  
Microelectrode Array

Investigation of The Initiation Site and Propagation of Epileptiform Discharges in Hippocampal Slices Using Microelectrode Array

2011 ◽  
Vol 37 (11) ◽  
pp. 1240-1247 ◽  
Author(s):  
Xin-Wei GONG ◽  
Fan YANG ◽  
Jian-Sheng LIU ◽  
Qin-Chi LU ◽  
Hai-Qing GONG ◽  
...  
Keyword(s):  
Microelectrode Array ◽  
Hippocampal Slices ◽  
Initiation Site ◽  
Epileptiform Discharges

scholarly journals CB1 antagonism increases excitatory synaptogenesis in a cortical spheroid model of fetal brain development

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Alexis Papariello ◽  
David Taylor ◽  
Ken Soderstrom ◽  
Karen Litwa
Keyword(s):  
Brain Development ◽  
Spontaneous Activity ◽  
Microelectrode Array ◽  
Cannabinoid Receptor ◽  
Fetal Brain ◽  
Endocannabinoid System ◽  
Autism Spectrum ◽  
Nervous System Development ◽  
Inhibitory Synapses ◽  
Fetal Brain Development

AbstractThe endocannabinoid system (ECS) plays a complex role in the development of neural circuitry during fetal brain development. The cannabinoid receptor type 1 (CB1) controls synaptic strength at both excitatory and inhibitory synapses and thus contributes to the balance of excitatory and inhibitory signaling. Imbalances in the ratio of excitatory to inhibitory synapses have been implicated in various neuropsychiatric disorders associated with dysregulated central nervous system development including autism spectrum disorder, epilepsy, and schizophrenia. The role of CB1 in human brain development has been difficult to study but advances in induced pluripotent stem cell technology have allowed us to model the fetal brain environment. Cortical spheroids resemble the cortex of the dorsal telencephalon during mid-fetal gestation and possess functional synapses, spontaneous activity, an astrocyte population, and pseudo-laminar organization. We first characterized the ECS using STORM microscopy and observed synaptic localization of components similar to that which is observed in the fetal brain. Next, using the CB1-selective antagonist SR141716A, we observed an increase in excitatory, and to a lesser extent, inhibitory synaptogenesis as measured by confocal image analysis. Further, CB1 antagonism increased the variability of spontaneous activity within developing neural networks, as measured by microelectrode array. Overall, we have established that cortical spheroids express ECS components and are thus a useful model for exploring endocannabinoid mediation of childhood neuropsychiatric disease.

Excitation spread in cardiac myocyte cultures using paired microelectrode and microelectrode array recordings

2007 ◽  
Vol 42 (6) ◽  
pp. S3 ◽  
Author(s):  
P. Athias ◽  
S. Jacquir ◽  
C. Tissier ◽  
D. Vandroux ◽  
S. Binczak ◽  
...  
Keyword(s):  
Microelectrode Array ◽  
Cardiac Myocyte ◽  
Array Recordings
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