Impact of fluorescence imaging in thyroid surgery (Conference Presentation)

2018 ◽  
Author(s):  
Eren Berber
Keyword(s):  
Fluorescence Imaging ◽  
Thyroid Surgery

scholarly journals Fluorescence Image-Guided Surgery for Thyroid Cancer: Utility for Preventing Hypoparathyroidism

Cancers ◽  
2021 ◽  
Vol 13 (15) ◽  
pp. 3792
Author(s):  
Marco Stefano Demarchi ◽  
Barbara Seeliger ◽  
Jean-Christophe Lifante ◽  
Pier Francesco Alesina ◽  
Frédéric Triponez
Keyword(s):  
Thyroid Cancer ◽  
Fluorescence Imaging ◽  
Thyroid Surgery ◽  
Parathyroid Glands ◽  
Review Of The Literature ◽  
Inclusion Criteria ◽  
Fluorescence Image ◽  
Guided Surgery ◽  
Fluorescence Guided Surgery

Background: Hypoparathyroidism is one of the most frequent complications of thyroid surgery, especially when associated with lymph node dissection in cases of thyroid cancer. Fluorescence-guided surgery is an emerging tool that appears to help reduce the rate of this complication. The present review aims to highlight the utility of fluorescence imaging in preserving parathyroid glands during thyroid cancer surgery. Methods: We performed a systematic review of the literature according to PRISMA guidelines to identify published studies on fluorescence-guided thyroid surgery with a particular focus on thyroid cancer. Articles were selected and analyzed per indication and type of surgery, autofluorescence or exogenous dye usage, and outcomes. The Methodological Index for Non-Randomized Studies (MINORS) was used to assess the methodological quality of the included articles. Results: Twenty-five studies met the inclusion criteria, with three studies exclusively assessing patients with thyroid cancer. The remaining studies assessed mixed cohorts with thyroid cancer and other thyroid or parathyroid diseases. The majority of the papers support the potential benefit of fluorescence imaging in preserving parathyroid glands in thyroid surgery. Conclusions: Fluorescence-guided surgery is useful in the prevention of post-thyroidectomy hypoparathyroidism via enhanced early identification, visualization, and preservation of the parathyroid glands. These aspects are notably beneficial in cases of associated lymphadenectomy for thyroid cancer.

scholarly journals Feasibility of indocyanine green fluorescence imaging for intraoperative identification of parathyroid glands during thyroid surgery

Head & Neck ◽  
2018 ◽  
Vol 41 (2) ◽  
pp. 340-348 ◽  
Author(s):  
Jacqueline van den Bos ◽  
Lottie van Kooten ◽  
Sanne M. E. Engelen ◽  
Tim Lubbers ◽  
Laurents P. S. Stassen ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Fluorescence Imaging ◽  
Thyroid Surgery ◽  
Parathyroid Glands ◽  
Green Fluorescence ◽  
Indocyanine Green Fluorescence ◽  
Indocyanine Green Fluorescence Imaging

The influence of confocal microscope design on imaging performance

1993 ◽  
Vol 51 ◽  
pp. 144-145
Author(s):  
C J R Sheppard
Keyword(s):  
Image Quality ◽  
Fluorescence Imaging ◽  
Confocal Microscope ◽  
Industrial Applications ◽  
Three Dimensions ◽  
Design Parameters ◽  
Weak Signals ◽  
Size And Shape ◽  
Imaging Performance ◽  
Fundamental Limitation

The confocal microscope is now widely used in both biomedical and industrial applications for imaging, in three dimensions, objects with appreciable depth. There are now a range of different microscopes on the market, which have adopted a variety of different designs. The aim of this paper is to explore the effects on imaging performance of design parameters including the method of scanning, the type of detector, and the size and shape of the confocal aperture.It is becoming apparent that there is no such thing as an ideal confocal microscope: all systems have limitations and the best compromise depends on what the microscope is used for and how it is used. The most important compromise at present is between image quality and speed of scanning, which is particularly apparent when imaging with very weak signals. If great speed is not of importance, then the fundamental limitation for fluorescence imaging is the detection of sufficient numbers of photons before the fluorochrome bleaches.

Ubiquinone-BODIPY nanoparticles for tumor redox-responsive fluorescence imaging and photodynamic activity

2021 ◽  
Author(s):  
Byunghee Hwang ◽  
Tae-Il Kim ◽  
Hyunjin Kim ◽  
Sungjin Jeon ◽  
Yongdoo Choi ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Selective Activation ◽  
Turn On ◽  
Intracellular Environment ◽  
Redox Responsive ◽  
Photodynamic Activity

A ubiquinone-BODIPY photosensitizer self-assembles into nanoparticles (PS-Q-NPs) and undergoes selective activation within the highly reductive intracellular environment of tumors, resulting in “turn-on” fluorescence and photosensitizing activities.

Is thyroid surgery performed too often in Germany?

2015 ◽  
Vol 54 (03) ◽  
pp. 101-105 ◽  
Author(s):  
F. A. Verburg
Keyword(s):  
Surgical Procedures ◽  
Thyroid Surgery ◽  
Needle Biopsy ◽  
Fine Needle Biopsy ◽  
Contributing Factors ◽  
Fine Needle ◽  
Diagnostic Measures ◽  
Frequent Use ◽  
Preoperative Diagnostic ◽  
The Usa

SummaryThyroid surgery is one of the more common surgical procedures in Germany. This is in contrast with the situation in some other countries, where this procedure is performed comparatively rarely. In this paper the number of thyroid surgeries in Germany is compared with other western countries (Netherlands, USA, England). In contrast to e. g. the USA and England the number of thyroid surgeries in Germany is declining, however with approximately 109/100 000/year in 2012 is still elevated (Netherlands: 16/100 000/year, USA: at least 42/100 000/year, England: at least 27/100 000/year).Possible contributing factors to this higher number of thyroid surgeries in Germany are explored. These factors include iodine deficiency, the frequent use of advanced diagnostics such as ultrasound, insufficient use of preoperative diagnostic measures such as fine needle biopsy and the practice of “defensive medicine”. How much each of these factors contributes is however unclear.

Transient voice changes following thyroid surgery and surgical efforts to minimize postoperative dysphonia

2006 ◽  
Vol 114 (S 1) ◽  
Author(s):  
TJ Musholt ◽  
PB Musholt ◽  
C Fottner ◽  
J Garm ◽  
U Napiontek ◽  
...  
Keyword(s):  
Thyroid Surgery ◽  
Voice Changes
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