Investigation of the mechanism for penetration of low density lipoprotein into the arterial wall

2018 ◽  
Author(s):  
Olga E. Glukhova ◽  
Artyom A. Zyktin ◽  
Michael M. Slepchenkov
Keyword(s):  
Arterial Wall ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Low Density

Oxidation of Plasma Low-Density Lipoprotein Accelerates Its Accumulation and Degradation in the Arterial Wall In Vivo

Circulation ◽  
1996 ◽  
Vol 94 (7) ◽  
pp. 1698-1704 ◽  
Author(s):  
Klaus Juul ◽  
Lars B. Nielsen ◽  
Klaus Munkholm ◽  
Steen Stender ◽  
Børge G. Nordestgaard
Keyword(s):  
Arterial Wall ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Low Density

Lipoprotein (a) displays increased accumulation compared with low-density lipoprotein in the murine arterial wall

1994 ◽  
Vol 67-68 ◽  
pp. 175-190 ◽  
Author(s):  
Jörg Kreuzer ◽  
Marcia B. Lloyd ◽  
Dean Bok ◽  
Gunther M. Fless ◽  
Angelo M. Scanu ◽  
...  
Keyword(s):  
Arterial Wall ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Low Density ◽  
Lipoprotein A

Oxidative modification of triacylglycerol-rich lipoproteins

2003 ◽  
Vol 31 (5) ◽  
pp. 1062-1065 ◽  
Author(s):  
I.S. Young ◽  
C. McFarlane ◽  
J. McEneny
Keyword(s):  
Particle Size ◽  
Fatty Acid Composition ◽  
Arterial Wall ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Oxidative Modification ◽  
Low Density ◽  
Lipoprotein Oxidation ◽  
Oxidative Reactions ◽  
Mediated Oxidation

Lipoprotein oxidation is thought to play a pivotal role in the evolution of atherosclerosis. Low-density lipoprotein (LDL) is the main source of oxidized lipid in the arterial wall. Oxidation of LDL alters its properties in a number of ways, making it more atherogenic, but oxidation of other lipoprotein classes may also be important. Common mechanisms are likely to contribute to the oxidation of all lipoprotein classes, with enzyme-mediated oxidation likely to be most important. Antioxidant content, fatty acid composition, particle size and the presence of seeding hydroperoxides also influence oxidative reactions. Larger triglyceride-rich lipoproteins are less likely to enter the arterial wall than LDL, but when oxidized will deliver a greater oxidant load to the arterial wall.

scholarly journals Enzymatic Modification of Low-Density Lipoprotein in the Arterial Wall

2004 ◽  
Vol 24 (11) ◽  
pp. 2130-2136 ◽  
Author(s):  
Michael Torzewski ◽  
Prapat Suriyaphol ◽  
Kerstin Paprotka ◽  
Lena Spath ◽  
Viola Ochsenhirt ◽  
...  
Keyword(s):  
Arterial Wall ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Low Density ◽  
Enzymatic Modification
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