All-optical intravascular probe for dual-mode photoacoustic imaging and optical coherence tomography (Conference Presentation)

Author(s):  
Sunish J. Mathews ◽  
Callum Little ◽  
Chris D. Loder ◽  
Roby D. Rakhit ◽  
Wenfeng Xia ◽  
...  
2016 ◽  
Vol 36 (1) ◽  
pp. 0111001
Author(s):  
谢炳凯 Xie Bingkai ◽  
刘少杰 Liu Shaojie ◽  
吴泳波 Wu Yongbo ◽  
唐志列 Tang Zhilie

2017 ◽  
Vol 10 (04) ◽  
pp. 1730006 ◽  
Author(s):  
Wei Qiao ◽  
Zhongjiang Chen

All-optically integrated photoacoustic (PA) and optical coherence tomography (OCT) dual-mode imaging technology that could offer comprehensive pathological information for accurate diagnosis in clinic has gradually become a promising imaging technology in the aspect of biomedical imaging during the recent years. This review refers to the technology aspects of all-optical PA detection and system evolution of optically integrated PA and OCT, including Michelson interferometer dual-mode imaging system, Fabry–Perot (FP) interferometer dual-mode imaging system and Mach–Zehnder interferometer dual-mode imaging system. It is believed that the optically integrated PA and OCT has great potential applications in biomedical imaging.


Sensors ◽  
2019 ◽  
Vol 19 (12) ◽  
pp. 2815 ◽  
Author(s):  
Karl Kratkiewicz ◽  
Rayyan Manwar ◽  
Ali Rajabi-Estarabadi ◽  
Joseph Fakhoury ◽  
Jurgita Meiliute ◽  
...  

The marked increase in the incidence of melanoma coupled with the rapid drop in the survival rate after metastasis has promoted the investigation into improved diagnostic methods for melanoma. High-frequency ultrasound (US), optical coherence tomography (OCT), and photoacoustic imaging (PAI) are three potential modalities that can assist a dermatologist by providing extra information beyond dermoscopic features. In this study, we imaged a swine model with spontaneous melanoma using these modalities and compared the images with images of nearby healthy skin. Histology images were used for validation.


2005 ◽  
Vol 44 (No. 26) ◽  
pp. L854-L856 ◽  
Author(s):  
Masato Ohmi ◽  
Kenji Nohara ◽  
Yoshihiro Ueda ◽  
Toshie Fuji ◽  
Masamitsu Haruna

2017 ◽  
Vol 10 (06) ◽  
pp. 1742007 ◽  
Author(s):  
L. Bartolini ◽  
F. Feroldi ◽  
J. J. A. Weda ◽  
M. Slaman ◽  
J. F. de Boer ◽  
...  

We present a multimodal ferrule-top sensor designed to perform the integrated epidetection of Optical Coherence Tomography (OCT) depth-profiles and micron-scale indentation by all-optical detection. By scanning a sample under the probe, we can obtain structural cross-section images and identify a region-of-interest in a nonhomogeneous sample. Then, with the same probe and setup, we can immediately target that area with a series of spherical-indentation measurements, in which the applied load is known with a [Formula: see text]N precision, the indentation depth with sub-[Formula: see text]m precision and a maximum contact radius of 100[Formula: see text][Formula: see text]m. Thanks to the visualization of the internal structure of the sample, we can gain a better insight into the observed mechanical behavior. The ability to impart a small, confined load, and perform OCT [Formula: see text]-scans at the same time, could lead to an alternative, high transverse resolution, Optical Coherence Elastography (OCE) sensor.


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