A multimodal imaging platform with integrated simultaneous photoacoustic microscopy, optical coherence tomography, optical Doppler tomography and fluorescence microscopy

2018 ◽  
Author(s):  
Arash Dadkhah ◽  
Nusrat Yeasmin ◽  
Jun Zhou ◽  
Shuliang Jiao
Keyword(s):  
Optical Coherence Tomography ◽  
Fluorescence Microscopy ◽  
Multimodal Imaging ◽  
Optical Coherence ◽  
Photoacoustic Microscopy ◽  
Doppler Tomography ◽  
Optical Doppler Tomography

scholarly journals Integrating photoacoustic microscopy, optical coherence tomography, OCT angiography, and fluorescence microscopy for multimodal imaging

2020 ◽  
Vol 245 (4) ◽  
pp. 342-347 ◽  
Author(s):  
Arash Dadkhah ◽  
Shuliang Jiao
Keyword(s):  
Optical Coherence Tomography ◽  
Fluorescence Microscopy ◽  
Multimodal Imaging ◽  
Imaging System ◽  
Optical Resolution ◽  
Biological Tissues ◽  
Large Field ◽  
Optical Coherence ◽  
Photoacoustic Microscopy

We have developed a multimodal imaging system, which integrated optical resolution photoacoustic microscopy, optical coherence tomography, optical coherence tomography angiography, and confocal fluorescence microscopy in one platform. The system is able to image complementary features of a biological sample by combining different contrast mechanisms. We achieved fast imaging and large field of view by combining optical scanning with mechanical scanning, similar to our previous publication. We have demonstrated the capability of the multimodal imaging system by imaging a mouse ear in vivo. Impact statement Photoacoustic microscopy-based multimodal imaging technology can provide high-resolution complementary information for biological tissues in vivo. It will potentially bring significant impact on the research and diagnosis of diseases by providing combined structural and functional information.

scholarly journals Simultaneous multimodal imaging with integrated photoacoustic microscopy and optical coherence tomography

2009 ◽  
Vol 34 (19) ◽  
pp. 2961 ◽  
Author(s):  
Shuliang Jiao ◽  
Zhixing Xie ◽  
Hao F. Zhang ◽  
Carmen A. Puliafito
Keyword(s):  
Optical Coherence Tomography ◽  
Multimodal Imaging ◽  
Optical Coherence ◽  
Photoacoustic Microscopy
Sign in / Sign up

Export Citation Format

Share Document