Noise modeling and recording condition optimization for practical holographic drive

Author(s):  
Takeru Utsugi ◽  
Kazuhiko Ono ◽  
Yukinobu Tada
2020 ◽  
Author(s):  
Clifford A. Brown ◽  
Jonny Dowdall ◽  
Brian Whiteaker ◽  
Lauren McIntyre

2010 ◽  
Vol 7 (7) ◽  
pp. 1-8
Author(s):  
N. Tokan ◽  
F. Güneş ◽  
F. Gürgen

Author(s):  
Yangyang Guo ◽  
Zhaoyu Qiao ◽  
Zhan Wang ◽  
Huijia Luo ◽  
Xi Wang

2021 ◽  
Vol 8 (1) ◽  
pp. 14
Author(s):  
Yu Zhang ◽  
Tsan-Yu Chiu ◽  
Jin-Tao Zhang ◽  
Shu-Jie Wang ◽  
Shu-Wen Wang ◽  
...  

Synthetic biology allows the re-engineering of biological systems and promotes the development of bioengineering to a whole new level, showing great potential in biomanufacturing. Here, in order to make the heterologous lycopene biosynthesis pathway compatible with the host strain YSy 200, we evolved YSy200 using a unique Synthetic Chromosome Rearrangement and Modification by LoxP-mediated Evolution (SCRaMbLE) system that is built in the Sc2.0 synthetic yeast. By inducing SCRaMbLE, we successfully identified a host strain YSy201 that can be served as a suitable host to maintain the heterologous lycopene biosynthesis pathway. Then, we optimized the lycopene biosynthesis pathway and further integrated into the rDNA arrays of YSy201 to increase its copy number. In combination with culturing condition optimization, we successfully screened out the final yeast strain YSy222, which showed a 129.5-fold increase of lycopene yield in comparison with its parental strain. Our work shows that, the strategy of combining the engineering efforts on both the lycopene biosynthesis pathway and the host strain can improve the compatibility between the heterologous pathway and the host strain, which can further effectively increase the yield of the target product.


IEEE Access ◽  
2021 ◽  
Vol 9 ◽  
pp. 102520-102541
Author(s):  
Husna Mutahira ◽  
Vladimir Shin ◽  
Mannan Saeed Muhammad ◽  
Dong Ryeol Shin

Author(s):  
Mohammad Javad Mohammadi ◽  
Abdolmajid Fadaei ◽  
Saeid Jalali ◽  
Hassan Shekoohmandi ◽  
Yusef Omidi Khaniabadi ◽  
...  

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