An optofluidic metasurface for lateral flow-through detection of cancer biomarker (Conference Presentation)

2018 ◽  
Author(s):  
Yifei Wang ◽  
Md Azahar Ali ◽  
Liang Dong ◽  
Meng Lu
Keyword(s):  
Cancer Biomarker ◽  
Lateral Flow ◽  
Flow Through

An optofluidic metasurface for lateral flow-through detection of breast cancer biomarker

2018 ◽  
Vol 107 ◽  
pp. 224-229 ◽  
Author(s):  
Yifei Wang ◽  
Md. Azahar Ali ◽  
Edmond K.C. Chow ◽  
Liang Dong ◽  
Meng Lu
Keyword(s):  
Breast Cancer ◽  
Cancer Biomarker ◽  
Lateral Flow ◽  
Flow Through

scholarly journals A Critical Comparison between Flow-through and Lateral Flow Immunoassay Formats for Visual and Smartphone-Based Multiplex Allergen Detection

Biosensors ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. 143 ◽  
Author(s):  
Georgina M. S. Ross ◽  
Gert IJ. Salentijn ◽  
Michel W. F. Nielen
Keyword(s):  
Test Line ◽  
Color Space ◽  
Lateral Flow ◽  
Critical Comparison ◽  
Passive Flow ◽  
Allergen Detection ◽  
Assay Time ◽  
Flow Through ◽  
Allergen Labeling ◽  
Active Flow

(1) Background: The lack of globally standardized allergen labeling legislation necessitates consumer-focused multiplexed testing devices. These should be easy to operate, fast, sensitive and robust. (2) Methods: Herein, we describe the development of three different formats for multiplexed food allergen detection, namely active and passive flow-through assays, and lateral flow immunoassays with different test line configurations. (3) Results: The fastest assay time was 1 min, whereas even the slowest assay was within 10 min. With the passive flow approach, the limits of detection (LOD) of 0.1 and 0.5 ppm for total hazelnut protein (THP) and total peanut protein (TPP) in spiked buffer were reached, or 1 and 5 ppm of THP and TPP spiked into matrix. In comparison, the active flow approach reached LODs of 0.05 ppm for both analytes in buffer and 0.5 and 1 ppm of THP and TPP spiked into matrix. The optimized LFIA configuration reached LODs of 0.1 and 0.5 ppm of THP and TPP spiked into buffer or 0.5 ppm for both analytes spiked into matrix. The optimized LFIA was validated by testing in 20 different blank and spiked matrices. Using device-independent color space for smartphone analysis, two different smartphone models were used for the analysis of optimized assays.

Lateral-Flow Effect on Endwall Heat Transfer and Pressure Drop in a Pin-Fin Trapezoidal Duct of Various Pin Shapes

2000 ◽  
Vol 123 (1) ◽  
pp. 133-139 ◽  
Author(s):  
Jenn-Jiang Hwang ◽  
Chau-Ching Lu
Keyword(s):  
Heat Transfer ◽  
Reynolds Number ◽  
Pressure Drop ◽  
Flow Rate ◽  
Lateral Flow ◽  
Transfer Enhancement ◽  
Pin Fin ◽  
Flow Reynolds Number ◽  
Outlet Flow ◽  
Flow Through

The effects of lateral-flow ejection 0<ε<1.0, pin shapes (square, diamond, and circular), and flow Reynolds number (6000<Re<40,000) on the endwall heat transfer and pressure drop for turbulent flow through a pin-fin trapezoidal duct are studied experimentally. A staggered pin array of five rows and five columns is inserted in the trapezoidal duct, with the same spacings between the pins in the streamwise and spanwise directions: Sx/d=Sy/d=2.5. Three different-shaped pins of length from 2.5<l/d<4.6 span the distance between two endwalls of the trapezoidal duct. Results reveal that the pin-fin trapezoidal duct with lateral-flow rate of ε=0.3-0.4 has a local minimum endwall-averaged Nusselt number and Euler number for all pin shapes investigated. The trapezoidal duct of lateral outlet flow only (ε=1.0) has the highest endwall heat transfer and pressure drop. Moreover, the square pin results in a better heat transfer enhancement than the diamond pin, and subsequently than the circular pin. Finally, taking account of the lateral-flow rate and the flow Reynolds number, the work develops correlations of the endwall-averaged heat transfer with three different pin shapes.

scholarly journals Subsurface Lateral Flow in Texture-Contrast (Duplex) Soils and Catchments with Shallow Bedrock

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Marcus A. Hardie ◽  
Richard B. Doyle ◽  
William E. Cotching ◽  
Shaun Lisson
Keyword(s):  
Preferential Flow ◽  
Soil Surface ◽  
Field Studies ◽  
Lateral Flow ◽  
Review Of Literature ◽  
Antecedent Soil Moisture ◽  
Process Understanding ◽  
Subsurface Lateral Flow ◽  
Flow Through ◽  
Texture Contrast

Development-perched watertables and subsurface lateral flows in texture-contrast soils (duplex) are commonly believed to occur as a consequence of the hydraulic discontinuity between the A and B soil horizons. However, in catchments containing shallow bedrock, subsurface lateral flows result from a combination of preferential flow from the soil surface to the soil—bedrock interface, undulations in the bedrock topography, lateral flow through macropore networks at the soil—bedrock interface, and the influence of antecedent soil moisture on macropore connectivity. Review of literature indicates that some of these processes may also be involved in the development of subsurface lateral flow in texture contrast soils. However, the extent to which these mechanisms can be applied to texture contrast soils requires further field studies. Improved process understanding is required for modelling subsurface lateral flows in order to improve the management of waterlogging, drainage, salinity, and offsite agrochemicals movement.

Disposable lateral flow-through strip for smartphone-camera to quantitatively detect alkaline phosphatase activity in milk

2015 ◽  
Vol 69 ◽  
pp. 307-315 ◽  
Author(s):  
Ling Yu ◽  
ZhuanZhuan Shi ◽  
Can Fang ◽  
YuanYuan Zhang ◽  
YingShuai Liu ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Phosphatase Activity ◽  
Alkaline Phosphatase Activity ◽  
Lateral Flow ◽  
Flow Through

Lateral flow through the sharp crested side rectangular weirs in open channels

2018 ◽  
Vol 59 ◽  
pp. 8-17 ◽  
Author(s):  
Ali Shariq ◽  
Ajmal Hussain ◽  
Mujib Ahmad Ansari
Keyword(s):  
Lateral Flow ◽  
Open Channels ◽  
Flow Through

Lateral-Flow Effect on Endwall Heat Transfer and Pressure Drop in a Pin-Fin Trapezoidal Duct of Various Pin Shapes

2000 ◽  
Author(s):  
Jenn-Jiang Hwang ◽  
Chau-Ching Lu
Keyword(s):  
Heat Transfer ◽  
Reynolds Number ◽  
Pressure Drop ◽  
Flow Rate ◽  
Lateral Flow ◽  
Transfer Enhancement ◽  
Pin Fin ◽  
Flow Reynolds Number ◽  
Outlet Flow ◽  
Flow Through

Effects of the lateral-flow ejection (0 ≦ ε ≦ 1.0), pin shapes (square, diamond and circular) and flow Reynolds number (6,000 ≦ Re ≦ 40,000) on the endwall heat transfer and pressure drop for turbulent flow through a pin-fin trapezoidal duct are studied experimentally. The trapezoidal duct are inserted with a staggered pin array of five rows and five columns, with the same spacings between the pins in streamwise and spanwise directions of Sx/d = Sy/d = 2.5. Three different-shaped pins of length from 2.5 < l/d < 4.6 span the distance between two endwalls of the trapezoidal duct. Results reveal that the pin-fin trapezoidal duct with a lateral-flow rate of ε = 0.3–0.4 has a local minimum endwall-averaged Nusselt number and Euler number for all pin shapes investigated. The trapezoidal duct of lateral outlet flow only (ε = 1.0) has the highest endwall heat transfer and pressure drop. Moreover, the square pin performs a better heat transfer enhancement than the diamond pin, and subsequently than the circular pin. Finally, taking account of the lateral-flow rate and the flow Reynolds number develops correlations of the endwall-averaged heat transfer for three different pin shapes.

Lateral Flow through a Parallel Gap Driven by Surface Hydrophilicity and Liquid Edge Pinning for Creating Microlens Array

2014 ◽  
Vol 6 (21) ◽  
pp. 18450-18456 ◽  
Author(s):  
Chengbao Jiang ◽  
Xiangming Li ◽  
Hongmiao Tian ◽  
Chunhui Wang ◽  
Jinyou Shao ◽  
...  
Keyword(s):  
Microlens Array ◽  
Lateral Flow ◽  
Surface Hydrophilicity ◽  
Flow Through
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