Viscoelastic characterization of dispersive media by inversion of a general wave propagation model in optical coherence elastography

Author(s):  
Fernando Zvietcovich ◽  
Maria Helguera ◽  
Diane Dalecki ◽  
Kevin J. Parker ◽  
Jannick P. Rolland ◽  
...  
2017 ◽  
Vol 10 (06) ◽  
pp. 1742008 ◽  
Author(s):  
Fernando Zvietcovich ◽  
Jannick P. Rolland ◽  
Kevin J. Parker

In the characterization of elastic properties of tissue using dynamic optical coherence elastography, shear/surface waves are propagated and tracked in order to estimate speed and Young’s modulus. However, for dispersive tissues, the displacement pulse is highly damped and distorted during propagation, diminishing the effectiveness of peak tracking approaches, and leading to biased estimates of wave speed. Further, plane wave propagation is sometimes assumed, which contributes to estimation errors. Therefore, we invert a wave propagation model that incorporates propagation, decay, and distortion of pulses in a dispersive media in order to accurately estimate its elastic and viscous components. The model uses a general first-order approximation of dispersion, avoiding the use of any particular rheological model of tissue. Experiments are conducted in elastic and viscoelastic tissue-mimicking phantoms by producing a Gaussian push using acoustic radiation force excitation and measuring the wave propagation using a Fourier domain optical coherence tomography system. Results confirmed the effectiveness of the inversion method in estimating viscoelastic parameters in both the viscoelastic and elastic phantoms when compared to mechanical measurements. Finally, the viscoelastic characterization of a fresh porcine cornea was conducted. Preliminary results validate this approach when compared to other methods.


1995 ◽  
Vol 17 (4) ◽  
pp. 6-12
Author(s):  
Nguyen Tien Dat ◽  
Dinh Van Manh ◽  
Nguyen Minh Son

A mathematical model on linear wave propagation toward shore is chosen and corresponding software is built. The wave transformation outside and inside the surf zone is considered including the diffraction effect. The model is tested by laboratory and field data and gave reasonables results.


2017 ◽  
Vol 14 ◽  
pp. 9-15 ◽  
Author(s):  
Hadeel Elayan ◽  
Raed M. Shubair ◽  
Josep Miquel Jornet ◽  
Raj Mittra

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