Real-time three-dimensional temperature mapping in photothermal therapy with optoacoustic tomography

2017 ◽  
Author(s):  
Francisco Javier Oyaga Landa ◽  
Xosé Luís Deán-Ben ◽  
Ronald Sroka ◽  
Daniel Razansky
Keyword(s):  
Real Time ◽  
Photothermal Therapy ◽  
Three Dimensional ◽  
Temperature Mapping ◽  
Optoacoustic Tomography

Simultaneous visualization of tumour oxygenation, neovascularization and contrast agent perfusion by real-time three-dimensional optoacoustic tomography

2015 ◽  
Vol 26 (6) ◽  
pp. 1843-1851 ◽  
Author(s):  
Vladimir Ermolayev ◽  
Xose Luis Dean-Ben ◽  
Subhamoy Mandal ◽  
Vasilis Ntziachristos ◽  
Daniel Razansky
Keyword(s):  
Contrast Agent ◽  
Real Time ◽  
Three Dimensional ◽  
Optoacoustic Tomography ◽  
Tumour Oxygenation ◽  
Simultaneous Visualization

scholarly journals Bedside 3D Visualization of Lymphatic Vessels with a Handheld Multispectral Optoacoustic Tomography Device

2020 ◽  
Vol 9 (3) ◽  
pp. 815 ◽  
Author(s):  
Guido Giacalone ◽  
Takumi Yamamoto ◽  
Florence Belva ◽  
Akitatsu Hayashi
Keyword(s):  
Real Time ◽  
Near Infrared ◽  
3D Visualization ◽  
Imaging Modality ◽  
Three Dimensional ◽  
Lymphatic Vessels ◽  
Secondary Lymphedema ◽  
Optoacoustic Tomography ◽  
Small Vessels ◽  
Promising Tool

Identification of lymphatics by Indocyanine Green (ICG) lymphography in patients with severe lymphedema is limited due to the overlying dermal backflow. Nor can the method detect deep and/or small vessels. Multispectral optoacoustic tomography (MSOT), a real-time three- dimensional (3D) imaging modality which allows exact spatial identification of absorbers in tissue such as blood and injected dyes can overcome these hurdles. However, MSOT with a handheld probe has not been performed yet in lymphedema patients. We conducted a pilot study in 11 patients with primary and secondary lymphedema to test whether lymphatic vessels could be detected with a handheld MSOT device. In eight patients, we could not only identify lymphatics and veins but also visualize their position and contractility. Furthermore, deep lymphatic vessels not traceable by ICG lymphography and lymphatics covered by severe dermal backflow, could be clearly identified by MSOT. In three patients, two of which had advanced stage lymphedema, only veins but no lymphatic vessels could be identified. We found that MSOT can identify and image lymphatics and veins in real-time and beyond the limits of near-infrared technology during a single bedside examination. Given its easy use and high accuracy, the handheld MSOT device is a promising tool in lymphatic surgery.

scholarly journals Noninvasive Real-Time Visualization of Multiple Cerebral Hemodynamic Parameters in Whole Mouse Brains Using Five-Dimensional Optoacoustic Tomography

2015 ◽  
Vol 35 (4) ◽  
pp. 531-535 ◽  
Author(s):  
Sven Gottschalk ◽  
Thomas Felix Fehm ◽  
Xosé Luís Deán-Ben ◽  
Daniel Razansky
Keyword(s):  
Real Time ◽  
Cerebral Blood Volume ◽  
Functional Neuroimaging ◽  
Three Dimensional ◽  
Blood Oxygenation ◽  
Hemodynamic Parameters ◽  
Label Free ◽  
Optoacoustic Tomography ◽  
Real Time Visualization ◽  
Tomographic Data

Current functional neuroimaging methods are not adequate for high-resolution whole-brain visualization of neural activity in real time. Here, we show imaging of fast hemodynamic changes in deep mouse brain using fully noninvasive acquisition of five-dimensional optoacoustic data from animals subjected to oxygenation stress. Multispectral video-rate acquisition of three-dimensional tomographic data enables simultaneous label-free assessment of multiple brain hemodynamic parameters, including blood oxygenation, total hemoglobin, cerebral blood volume, oxygenized and deoxygenized hemoglobin, in real time. The unprecedented results indicate that the proposed methodology may serve as a powerful complementary, and potentially superior, method for functional neuroimaging studies in rodents.

Evaluation of the mitral valve by transthoracic real-time three-dimensional echocardiography

2010 ◽  
Vol 151 (21) ◽  
pp. 854-863 ◽  
Author(s):  
Attila Nemes ◽  
Marcel L. Geleijnse ◽  
Osama I. I. Soliman ◽  
Wim B. Vletter ◽  
Jackie S. McGhie ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Real Time ◽  
Three Dimensional ◽  
Dimensional Echocardiography ◽  
Three Dimensional Echocardiography

Jelenleg az echokardiográfia a legszéleskörűbben alkalmazott rutin noninvazív diagnosztikus eljárás, amelynek segítségével a mitralis billentyű morfológiája és funkciója jellemezhető. Ennek az összefoglaló jellegű közleménynek a célja az egyik legújabb echokardiográfiás fejlesztés, a transthoracalis real-time háromdimenziós echokardiográfia szerepének bemutatása a mitralis billentyű vizsgálatában.

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