scholarly journals New opportunities of differential diagnosis of biological tissues polycrystalline structure using methods of Stokes correlometry mapping of polarization inhomogeneous images

2017 ◽  
Author(s):  
L. Trifonyuk ◽  
O. G. Prydiy ◽  
M. Grytsyuk ◽  
L. Kushnerik ◽  
Olexander V. Dubolazov ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Biological Tissues ◽  
Polycrystalline Structure

scholarly journals Stokes-Correlometry Analysis of Biological Tissues With Polycrystalline Structure

2019 ◽  
Vol 25 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Alexander Ushenko ◽  
Anton Sdobnov ◽  
Alexander Dubolazov ◽  
Marta Grytsiuk ◽  
Yuriy Ushenko ◽  
...  
Keyword(s):  
Biological Tissues ◽  
Polycrystalline Structure

Mueller-matrix mapping of biological tissues in differential diagnosis of optical anisotropy mechanisms of protein networks

2015 ◽  
Vol 45 (3) ◽  
pp. 265-269 ◽  
Author(s):  
V A Ushenko ◽  
M I Sidor ◽  
Yu F Marchuk ◽  
N V Pashkovskaya ◽  
D R Andreichuk
Keyword(s):  
Differential Diagnosis ◽  
Optical Anisotropy ◽  
Biological Tissues ◽  
Mueller Matrix ◽  
Protein Networks ◽  
Matrix Mapping

scholarly journals Polarization-interference mapping of networks in diffusal polycristaline biological tissues

2019 ◽  
Keyword(s):  
Experimental Testing ◽  
Physiological State ◽  
Morphological Structure ◽  
Biological Tissues ◽  
Mapping Method ◽  
Polycrystalline Structure ◽  
Matrix Mapping ◽  
Stokes Polarimetry ◽  
Rates Of Growth ◽  
Holographic Reconstruction

Objectives: Development and experimental testing of the complex of Stokes-polarimetry and interferometry methods using algorithms for digital holographic reconstruction of the amplitude-phase structure of object fields for obtaining interrelationships between 3D distributions of depolarization maps and peculiarities of the polycrystalline structure of histological sections of biological tissues of different morphological structures and physiological state. Materials and methods: The basis of the 3D Müller-matrix mapping method is the use of a reference wave of laser radiation, which is superimposed on a polarization-non-uniform image of the biological layer in the scheme of the optical interferometer. Results: In the process of comparative analysis of the map of depolarization of biological tissues with different geometric scales of the morphological structure, we found different rates of growth of the degree of depolarization.

scholarly journals Differential Mueller matrix imaging of partially depolarizing optically anisotropic biological tissues

2019 ◽  
Vol 35 (4) ◽  
pp. 877-891 ◽  
Author(s):  
L. Trifonyuk ◽  
A. Sdobnov ◽  
W. Baranowski ◽  
V. Ushenko ◽  
O. Olar ◽  
...  
Keyword(s):  
Biological Tissues ◽  
Mueller Matrix ◽  
Differential Diagnostics ◽  
Matrix Elements ◽  
Polycrystalline Structure ◽  
First Order ◽  
Histological Sections ◽  
Laser Polarimetry ◽  
Matrix Mapping ◽  
Differential Matrix

AbstractSince recently, a number of innovative polarization-based optical imaging modalities have been introduced and extensively used in various biomedical applications, with an ultimate aim to attain the practical tool for the optical biopsy and functional characterization of biological tissues. The techniques utilize polarization properties of light and Mueller matrix mapping of microscopic images of histological sections of biological tissues or polycrystalline films of biological fluids. The main drawback of currently developed laser polarimetry approaches and Mueller matrix mapping techniques is poor reproducibility of experimental data. This is due to azimuthal dependence of polarization and ellipticity values of most matrix elements to sample orientation in respect to incidence light polarization. Current study aims to generalize the methods of laser polarimetry for diagnosis of partially depolarizing optically anisotropic biological tissues. A method of differential Mueller matrix mapping for reconstruction of linear and circular birefringence and dichroism parameter distributions of partially depolarizing layers of biological tissues of different morphological structure is introduced and practically implemented. The coordinate distributions of the value of the first-order differential matrix elements of histological sections of brain tissue with spatially structured, optically anisotropic fibrillar network, as well as of parenchymatous tissue of the rectum wall with an “islet” polycrystalline structure are determined. Within the statistical analysis of polarization reproduced distributions of the averaged parameters of phase and amplitude anisotropy, the significant sensitivity of the statistical moments of the third and fourth orders to changes in the polycrystalline structure of partially depolarizing layers of biological tissue is observed. The differentiation of female reproductive sphere connective tissue is realized with excellent accuracy. The differential Mueller matrix mapping method for reconstruction of distributions of linear and circular birefringence and dichroism parameters of partially depolarizing layers of biological tissues of different morphological structures is proposed and substantiated. Differential diagnostics of changes in the phase (good balanced accuracy) and amplitude (excellent balanced accuracy) of the anisotropy of the partially depolarizing layers of the vagina wall tissue with prolapse of the genitals is realized. The maximum diagnostic efficiency of the first-order differential matrix method was demonstrated in comparison with the traditional methods of polarization and Mueller matrix mapping of histological sections of light-scattering biological tissues.

scholarly journals FORENSIC MEDICAL CRITERIA OF DIFFERENTIAL DIAGNOSIS OF ALCOHOL AND CARBON MONOXIDE POISONING BY USING AZIMUTHAL-INVARIANT POLARIZATION MUELLER-MATRIX MICROSCOPY

2021 ◽  
Vol 2 ◽  
pp. 33-40
Author(s):  
Olexandr Harazdiuk ◽  
Ihor Ivaskevich ◽  
Oleh Vanchuliak ◽  
Yuliia Sarkisova
Keyword(s):  
Carbon Monoxide ◽  
Differential Diagnosis ◽  
Cause Of Death ◽  
Human Body ◽  
Carbon Monoxide Poisoning ◽  
Biological Tissues ◽  
Mueller Matrix ◽  
Histological Sections ◽  
Common Causes ◽  
Characteristic Features

Introduction: Fatal intoxications with alcohol and carbon monoxide are the most common causes of poisoning that occur in forensic medical practice. Therefore, the differential diagnosis of these intoxications is extremely important. To solve this problem, we propose the use of the method of azimuthal-invariant polarization Mueller-matrix microscopy of histological sections of biological tissues (BT). Objectives: The purpose of the study was to establish statistically significant criteria for differentiation of the cause of death in case of alcohol poisoning (AP) and carbon monoxide poisoning (CMP) by using azimuthal-invariant polarization Mueller-matrix microscopy of polycrystalline fractions of histological sections of organs and blood films of the human body. Results: A number of characteristic features have been identified that have not been previously described and allow to objectively differentiate the cause of death in the case of AP and CMP, namely Ek – 0.95±0.045 and 1.81±0.092 in the study of histological sections of the myocardium;  Ek – 0,19±0,011 and 1,11±0,094 – polycrystalline blood films. Analysis of the obtained data revealed a good level of accuracy in the study of histological sections of the myocardium (As 85%) and polycrystalline blood films (As 88%). Conclusion: Thus, developed and tested method of azimuthal-invariant polarization Mueller-matrix microscopy allows to differentiate the cause of death in cases of AP and CMP.

scholarly journals Digital interferometric polarimetry of the polycrystalline structure for differential diagnosis of prostate tumors

2021 ◽  
Vol 32 ◽  
pp. O4-O5
Author(s):  
L. Tryfonyuk ◽  
O. Voronina ◽  
A. Strashkievich ◽  
O. Ushenko ◽  
N. Pavlukovich ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Polycrystalline Structure ◽  
Prostate Tumors
Sign in / Sign up

Export Citation Format

Share Document