Property modification of nafion via polymer blending with polyimide (Conference Presentation)

Author(s):  
Taeseon Hwang ◽  
Jungsoo Nam ◽  
Dong-Chan Lee ◽  
Kwang Jin Kim
2017 ◽  
Author(s):  
Jeremy Roach ◽  
Yusuke Sasano ◽  
Cullen Schmid ◽  
Saheem Zaidi ◽  
Vsevolod Katritch ◽  
...  

Salvinorin A (SalA) is a plant metabolite that agonizes the human <i>kappa</i>-opioid receptor (κ-OR) with high affinity and high selectivity over <i>mu- </i>and <i>delta-</i>opioid receptors. Its therapeutic potential has stimulated extensive semi-synthetic studies and total synthesis campaigns. However, structural modification of SalA has been complicated by its instability, and efficient total synthesis has been frustrated by its dense, complex architecture. Treatment of strategic bonds in SalA as dynamic and dependent on structural perturbation enabled the identification of an efficient retrosynthetic pathway. Here we show that deletion of C20 simultaneously stabilizes the SalA skeleton, simplifies its synthesis and retains its high affinity and selectivity for the κ-OR. The resulting 10-step synthesis now opens the SalA scaffold to deep-seated property modification.


2021 ◽  
Vol 26 ◽  
pp. 102027
Author(s):  
Elnaz Esmizadeh ◽  
Ali Vahidifar ◽  
Sahar Shojaie ◽  
Ghasem Naderi ◽  
Mohammad Reza Kalaei ◽  
...  

Vacuum ◽  
2021 ◽  
Vol 187 ◽  
pp. 110105
Author(s):  
I.V. Vasenina ◽  
O.A. Laput ◽  
I.A. Kurzina

2013 ◽  
Vol 25 (2) ◽  
pp. 675-681
Author(s):  
Xu Wang ◽  
Lichao Li ◽  
Deben Chen ◽  
Anyong Zhong

2011 ◽  
Vol 694 ◽  
pp. 341-344
Author(s):  
Li Jun Wang ◽  
Jie Qiong Li ◽  
Hong Jing Wang

Application of nanocrystalline magnetic materials in electromechanical devices is increasingly being adopted, helping to solve energy-saving problems and global warming. Compared with conventional silicon steel materials, nanocrystalline materials show faster flux reversal, lower magnetic loss and more versatile property modification, which result in the successful application in modern electronic devices. Nanocrystalline magnetic materials will be increasingly popularized and used in power electronics, telecommunication equipment and electronic article surveillance systems due to the demands for smaller and efficient devices in the future.


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