On the nature of data collection for soft-tissue image-to-physical organ registration: a noise characterization study

2017 ◽  
Author(s):  
Jarrod A. Collins ◽  
Jon S. Heiselman ◽  
Jared A. Weis ◽  
Logan W. Clements ◽  
Amber L. Simpson ◽  
...  
2009 ◽  
Vol 22 (04) ◽  
pp. 321-324 ◽  
Author(s):  
C. Hall ◽  
N. Trentacosta ◽  
M. Percival ◽  
I. Levy

Summary Objectives: Little is known about the risks of injury to dogs participating in the relatively new sport of canine agility. The purpose of this study was to identify the factors that put the participating dog at risk as well as determine the anatomical sites that were most commonly injured. Methods: A retrospective survey using a paper and web-based data collection instrument was used to evaluate dogs participating in the sport of canine agility. Results: Of the 1627 dogs included in the study, 33% were injured, and of those 58% were injured in competition. Most injuries occurred on dry outdoor surfaces. Border Collies were the most commonly injured, and injuries were in excess of what would be expected from their exposure. For all dogs, soft tissue injuries were most common. The shoulders and backs of dogs were most commonly injured. Dogs were most commonly injured by contact with an obstacle. The A-frame, dogwalk and bar jump obstacles were responsible for nearly two-thirds of injuries that resulted from contact with the obstacle. Conclusions: Border Collies are at higher risk for injury than would be expected from their exposure. The A-frame, dogwalk and bar jump obstacles put the shoulders and backs of dogs at risk. Clinical Relevance: For the first time, this study gives us insight into injuries occurring in dogs participating in canine agility. This will help direct prospective studies that evaluate the safety of individual obstacles, direct rule changes and enable practitioners to understand the risks of the sport.


2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 226-227
Author(s):  
Katherine Bishop ◽  
Karly N Anderson ◽  
Sarah Albers ◽  
Kaysie Allen ◽  
Christina Huber ◽  
...  

Abstract The objective of this project was to determine the impact of cooling on the soft tissue thickness, cranial thickness, and cross-sectional brain area of cadaver heads from market pigs. Documenting the effect of cooling on tissue dimensions of swine heads is valuable and important for future investigations of physical stunning and euthanasia methods that use cadaver heads. Cadaver heads were sourced from market pigs stunned with CO2. After transport to the data collection location, a captive bolt shot was applied in the frontal position. Following captive bolt application, each head (n=36) underwent an UNCHILLED and CHILLED treatment. The UNCHILLED treatment involved images collected immediately after splitting the head along the bolt path and the CHILLED treatment involved images of the same heads after storage in a walk-in cooler for 24 h at 2–4°C. All measurements for each treatment were determined from images of the heads cut along the plane of the bolt path immediately prior to and immediately after the refrigeration treatment. Measurements were performed by two observers; across all measurements, mean interobserver percent coefficient of variation (%CV) was 11.3±0.6%. The soft tissue posterior to the bolt path was different (P=0.0120) between treatments (CHILLED: 6.4±0.2mm; UNCHILLED: 7.2±0.2mm). The soft tissue thickness anterior to the bolt path was different (P=0.0378) between treatments (CHILLED: 5.5±0.2mm; UNCHILLED: 6.1±0.2mm). There was not a significant difference (P=0.8659) in cranial thickness posterior to the bolt path (CHILLED: 18.1±0.6mm; UNCHILLED: 18.3±0.6mm), nor was there a significant difference (P=0.2593) in cranial thickness anterior to the bolt path between treatments (CHILLED: 16.2±0.6mm; UNCHILLED: 15.2±0.6mm). Cross-sectional brain area did not differ (P=0.0737) (CHILLED: 3633.4±44.1mm; UNCHILLED: 3519.9±44.1mm). A correction factor of 1.12 was determined from this study for cases where estimation of UNCHILLED soft tissue thickness from CHILLED soft tissue thickness is necessary.


1993 ◽  
Vol 30 (4) ◽  
pp. 414-415 ◽  
Author(s):  
Mohd Ashraf Darzi ◽  
Nisar Ahmad Chowdri

The oblique facial cleft is an extremely rare and disfiguring congenital anomaly of the face. Tessier (1990) proposed an anatomic classification of the facial, craniofacial, and laterofacial clefts that was a great advance in the study of these clefts. The clefts were found to occur with an incidence of 1.43 to 4.85 in 100,000 births (Kawamoto, 1976). The exact incidence of these unusual facial clefts is unknown, and estimates vary widely because of the rarity of their occurrence and the lack of standard methods of data collection. To adequately examine the occurrence of oblique clefts, the medical community must be aware of the problem, and new cases should be presented. On the basis of clinical, radiologic, and surgical examinations, soft tissue and skeletal disruptions of three patients with the most rare craniofacial clefts (Tessier 3, 4, 5, and 9) are presented.


2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Karly N Anderson ◽  
Sarah E Albers ◽  
Kaysie J Allen ◽  
Katherine D Bishop ◽  
Brian J Greco ◽  
...  

Abstract The objective of this project was to determine the impact of cooling on the soft tissue thickness, cranial thickness, and cross-sectional brain area of cadaver heads from market pigs. Documenting the effect of cooling on tissue dimensions of swine heads is valuable and important for future investigations of physical stunning and euthanasia methods that use cadaver heads. Scalded and dehaired cadaver heads with intact jowls were sourced from market pigs stunned with CO2 gas. After transport to the data collection location, a penetrating captive bolt (PCB) shot (Jarvis Model PAS—Type P 0.25R Caliber Captive Bolt Pistol with Medium Rod Assembly and Blue Powder Cartridges) was applied in the frontal position. Following PCB application, each head (n = 36) underwent an UNCHILLED treatment followed by CHILLED treatment. The UNCHILLED treatment involved images collected immediately after splitting each head along the bolt path, and the CHILLED treatment involved images of the same heads after storage in a walk-in cooler for 24 h at 2 to 4°C. All measurements for each treatment were collected from images of the heads on the plane of the bolt path immediately prior to and immediately after the refrigeration treatment. Measurements were performed by two observers. Across all measurements, mean interobserver coefficient of variation was 11.3 ± 0.6%. The soft tissue caudal to the bolt path was different (P = 0.0120) between treatments (CHILLED: 6.4 ± 0.2 mm; UNCHILLED: 7.2 ± 0.2 mm). The soft tissue thickness rostral to the bolt path was different (P = 0.0378) between treatments (CHILLED: 5.5 ± 0.2 mm; UNCHILLED: 6.1 ± 0.2 mm). Cranial thickness caudal to the bolt path was not different (P = 0.8659; CHILLED: 18.1 ± 0.6 mm; UNCHILLED: 18.3 ± 0.6 mm), nor was there a significant difference (P = 0.2593) in cranial thickness rostral to the bolt path between treatments (CHILLED: 16.2 ± 0.6 mm; UNCHILLED: 15.2 ± 0.6 mm). Cross-sectional brain area did not differ (P = 0.0737; CHILLED: 3633.4 ± 44.1 mm; UNCHILLED: 3519.9 ± 44.1 mm). A correction factor of 1.12 was determined from this study for cases where estimation of UNCHILLED soft tissue thickness from CHILLED soft tissue thickness is necessary.


Author(s):  
S.W. Hui ◽  
D.F. Parsons

The development of the hydration stages for electron microscopes has opened up the application of electron diffraction in the study of biological membranes. Membrane specimen can now be observed without the artifacts introduced during drying, fixation and staining. The advantages of the electron diffraction technique, such as the abilities to observe small areas and thin specimens, to image and to screen impurities, to vary the camera length, and to reduce data collection time are fully utilized. Here we report our pioneering work in this area.


Author(s):  
D. C. Swartzendruber ◽  
Norma L. Idoyaga-Vargas

The radionuclide gallium-67 (67Ga) localizes preferentially but not specifically in many human and experimental soft-tissue tumors. Because of this localization, 67Ga is used in clinical trials to detect humar. cancers by external scintiscanning methods. However, the fact that 67Ga does not localize specifically in tumors requires for its eventual clinical usefulness a fuller understanding of the mechanisms that control its deposition in both malignant and normal cells. We have previously reported that 67Ga localizes in lysosomal-like bodies, notably, although not exclusively, in macrophages of the spocytaneous AKR thymoma. Further studies on the uptake of 67Ga by macrophages are needed to determine whether there are factors related to malignancy that might alter the localization of 67Ga in these cells and thus provide clues to discovering the mechanism of 67Ga localization in tumor tissue.


Author(s):  
J. P. Brunschwig ◽  
R. M. McCombs ◽  
R. Mirkovic ◽  
M. Benyesh-Melnick

A new virus, established as a member of the herpesvirus group by electron microscopy, was isolated from spontaneously degenerating cell cultures derived from the kidneys and lungs of two normal tree shrews. The virus was found to replicate best in cells derived from the homologous species. The cells used were a tree shrew cell line, T-23, which was derived from a spontaneous soft tissue sarcoma. The virus did not multiply or did so poorly for a limited number of passages in human, monkey, rodent, rabbit or chick embryo cells. In the T-23 cells, the virus behaved as members of the subgroup B of herpesvirus, in that the virus remained primarily cell associated.


Author(s):  
Weiping Liu ◽  
Jennifer Fung ◽  
W.J. de Ruijter ◽  
Hans Chen ◽  
John W. Sedat ◽  
...  

Electron tomography is a technique where many projections of an object are collected from the transmission electron microscope (TEM), and are then used to reconstruct the object in its entirety, allowing internal structure to be viewed. As vital as is the 3-D structural information and with no other 3-D imaging technique to compete in its resolution range, electron tomography of amorphous structures has been exercised only sporadically over the last ten years. Its general lack of popularity can be attributed to the tediousness of the entire process starting from the data collection, image processing for reconstruction, and extending to the 3-D image analysis. We have been investing effort to automate all aspects of electron tomography. Our systems of data collection and tomographic image processing will be briefly described.To date, we have developed a second generation automated data collection system based on an SGI workstation (Fig. 1) (The previous version used a micro VAX). The computer takes full control of the microscope operations with its graphical menu driven environment. This is made possible by the direct digital recording of images using the CCD camera.


1997 ◽  
Vol 6 (4) ◽  
pp. 34-47 ◽  
Author(s):  
Steven H. Long ◽  
Lesley B. Olswang ◽  
Julianne Brian ◽  
Philip S. Dale

This study investigated whether young children with specific expressive language impairment (SELI) learn to combine words according to general positional rules or specific, grammatic relation rules. The language of 20 children with SELI (4 females, 16 males, mean age of 33 months, mean MLU of 1.34) was sampled weekly for 9 weeks. Sixteen of these children also received treatment for two-word combinations (agent+action or possessor+possession). Two different metrics were used to determine the productivity of combinatorial utterances. One metric assessed productivity based on positional consistency alone; another assessed productivity based on positional and semantic consistency. Data were analyzed session-by-session as well as cumulatively. The results suggest that these children learned to combine words according to grammatic relation rules. Results of the session-by-session analysis were less informative than those of the cumulative analysis. For children with SELI ready to make the transition to multiword utterances, these findings support a cumulative method of data collection and a treatment approach that targets specific grammatic relation rules rather than general word combinations.


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