Detection of ICG at low concentrations by photoacoustic imaging system using LED light source

2017 ◽  
Author(s):  
Yusuke Shigeta ◽  
Toshitaka Agano ◽  
Naoto Sato ◽  
Hitoshi Nakatsuka ◽  
Kazuo Kitagawa ◽  
...  
Keyword(s):  
Light Source ◽  
Imaging System ◽  
Photoacoustic Imaging ◽  
Led Light ◽  
Low Concentrations

Development of environmentally friendly LED light source module for photoacoustic imaging system

2015 ◽  
Author(s):  
Toshitaka Agano ◽  
Naoto Sato ◽  
Hitoshi Nakatsuka ◽  
Kazuo Kitagawa ◽  
Takamitsu Hanaoka ◽  
...  
Keyword(s):  
Light Source ◽  
Imaging System ◽  
Photoacoustic Imaging ◽  
Environmentally Friendly ◽  
Led Light

An active hyperspectral imaging system based on a multi-LED light source

2019 ◽  
Vol 90 (2) ◽  
pp. 026107
Author(s):  
Huijie Wang ◽  
Yifan Hu ◽  
Xiangyun Ma ◽  
Jinglai Sun ◽  
Xueqing Sun ◽  
...  
Keyword(s):  
Light Source ◽  
Hyperspectral Imaging ◽  
Imaging System ◽  
Led Light

Photoacoustic imaging of clinical metal needle by a LED light source integrated transducer

2016 ◽  
Author(s):  
Toshitaka Agano ◽  
Naoto Sato ◽  
Hitoshi Nakatsuka ◽  
Kazuo Kitagawa ◽  
Takamitsu Hanaoka ◽  
...  
Keyword(s):  
Light Source ◽  
Photoacoustic Imaging ◽  
Led Light ◽  
Metal Needle

scholarly journals Analysis on High-Power Seaport LED Luminaire with Uniform Light Distribution Based on Optimized Lens and Heatsink

2021 ◽  
Vol 11 (9) ◽  
pp. 4035
Author(s):  
Jinsheon Kim ◽  
Jeungmo Kang ◽  
Woojin Jang
Keyword(s):  
Light Source ◽  
High Power ◽  
Heat Dissipation ◽  
Light Emitting Diode ◽  
Light Distribution ◽  
Light Sources ◽  
Led Light ◽  
High Power Led ◽  
Distribution Requirement ◽  
Lighting Application

In the case of light-emitting diode (LED) seaport luminaires, they should be designed in consideration of glare, average illuminance, and overall uniformity. Although it is possible to implement light distribution through auxiliary devices such as reflectors, it means increasing the weight and size of the luminaire, which reduces the feasibility. Considering the special environment of seaport luminaires, which are installed at a height of 30 m or more, it is necessary to reduce the weight of the device, facilitate replacement, and secure a light source with a long life. In this paper, an optimized lens design was investigated to provide uniform light distribution to meet the requirement in the seaport lighting application. Four types of lens were designed and fabricated to verify the uniform light distribution requirement for the seaport lighting application. Using numerical analysis, we optimized the lens that provides the required minimum overall uniformity for the seaport lighting application. A theoretical analysis for the heatsink structure and shape were conducted to reduce the heat from the high-power LED light sources up to 250 W. As a result of these analyses on the heat dissipation characteristics of the high-power LED light source used in the LED seaport luminaire, the heatsink with hexagonal-shape fins shows the best heat dissipation effect. Finally, a prototype LED seaport luminaire with an optimized lens and heat sink was fabricated and tested in a real seaport environment. The light distribution characteristics of this prototype LED seaport luminaire were compared with a commercial high-pressure sodium luminaire and metal halide luminaire.

scholarly journals Photothermal Therapy Using Gold Nanorods and Near-Infrared Light in a Murine Melanoma Model Increases Survival and Decreases Tumor Volume

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Mary K. Popp ◽  
Imane Oubou ◽  
Colin Shepherd ◽  
Zachary Nager ◽  
Courtney Anderson ◽  
...  
Keyword(s):  
Light Source ◽  
Gold Nanorods ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Tumor Volume ◽  
Infrared Light ◽  
Led Light ◽  
Murine Melanoma ◽  
Nir Light ◽  
Melanoma Model

Photothermal therapy (PTT) treatments have shown strong potential in treating tumors through their ability to target destructive heat preferentially to tumor regions. In this paper we demonstrate that PTT in a murine melanoma model using gold nanorods (GNRs) and near-infrared (NIR) light decreases tumor volume and increases animal survival to an extent that is comparable to the current generation of melanoma drugs. GNRs, in particular, have shown a strong ability to reach ablative temperatures quickly in tumors when exposed to NIR light. The current research tests the efficacy of GNRs PTT in a difficult and fast growing murine melanoma model using a NIR light-emitting diode (LED) light source. LED light sources in the NIR spectrum could provide a safer and more practical approach to photothermal therapy than lasers. We also show that the LED light source can effectively and quickly heatin vitroandin vivomodels to ablative temperatures when combined with GNRs. We anticipate that this approach could have significant implications for human cancer therapy.

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