Nanoimprint lithography-based plasmonic crystal-surface enhanced Raman scattering substrate for point of care testing application

2017 ◽  
Author(s):  
Tatsuro Endo ◽  
Kenji Yamada
Nanomaterials ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 2228
Author(s):  
Boris Khlebtsov ◽  
Nikolai Khlebtsov

Lateral flow immunoassays (LFIAs) have been developed and used in a wide range of applications, in point-of-care disease diagnoses, environmental safety, and food control. However, in its classical version, it has low sensitivity and can only perform semiquantitative detection, based on colorimetric signals. Over the past decade, surface-enhanced Raman scattering (SERS) tags have been developed in order to decrease the detection limit and enable the quantitative analysis of analytes. Of note, these tags needed new readout systems and signal processing algorithms, while the LFIA design remained unchanged. This review highlights SERS strategies of signal enhancement for LFIAs. The types of labels used, the possible gain in sensitivity from their use, methods of reading and processing the signal, and the prospects for use are discussed.


2022 ◽  
Author(s):  
Yingjie Hang ◽  
Jennifer Boryczka ◽  
Nianqiang Wu

This article reviews the principles, design and applications of visible-light and near-infrared fluorescence and surface-enhanced Raman scattering in point-of-care testing and bio-imaging.


2021 ◽  
Vol 9 ◽  
Author(s):  
Steven Quarin ◽  
Pietro Strobbia

The ability to accurately diagnose at the point of care is crucial in many pathologies. However, current standard diagnostic practices can only be performed in specialized health or laboratory settings. To move diagnostic methods from a specialized lab to the point of care many alternate methods have been developed and proposed. Among them surface-enhanced Raman scattering (SERS) sensing offers advantageous features, such as simultaneous detection of multiple biotargets and increased accuracy. Many groups have been working towards the translation of SERS sensing methods from the lab to the point of need. In this mini review, we discuss interesting and recent developments in this effort, focusing on how different sensing mechanism can be used in point-of-care testing applications of SERS.


Author(s):  
Maria João Oliveira ◽  
Inês Cunha ◽  
Miguel Peixoto de Almeida ◽  
Tomás Calmeiro ◽  
Elvira Fortunato ◽  
...  

The development of robust and sensitive point-of-care testing platforms is necessary to improve patient care and outcomes. Surface-Enhanced Raman Scattering (SERS)-based immunosensors are especially suited for this purpose. Here, we...


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