Lymph node detection in IASLC-defined zones on PET/CT images

2016 ◽  
Author(s):  
Yihua Song ◽  
Jayaram K. Udupa ◽  
Dewey Odhner ◽  
Yubing Tong ◽  
Drew A. Torigian
Keyword(s):  
Lymph Node ◽  
Ct Images ◽  
Pet Ct

PET-CT Gamma Probe-Guided Lymph Node Biopsy: A New Diagnostic Surgical Approach

2017 ◽  
Vol 103 (1_suppl) ◽  
pp. S34-S36
Author(s):  
Antonio Piñero-Madrona ◽  
Jorge Luis Monserrat-Coll ◽  
José Ruiz-Pardo ◽  
Juan Cabezas-Herrera ◽  
Francisco Nicolás-Ruiz
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Surgical Approach ◽  
Gamma Probe ◽  
Ct Images ◽  
Lymph Node Biopsy ◽  
Diagnostic Tools ◽  
Biopsy Technique ◽  
Node Biopsy ◽  
Pet Ct

Purpose The higher sensitivity of new diagnostic tools makes it easier to detect relapse in asymptomatic stages when classic procedures of lymph node biopsies are difficult to perform. The aim of this article is to describe the combination of gamma probe and 18F-FDG positron emission tomography-computed tomography (PET-CT) images in combination with sentinel lymph node biopsy technique for detection of nonpalpable lymph nodes. Methods After a dose of 18F-FDG was administered and PET-CT images that showed the location of suspected pathologic lymph nodes were obtained, transcutaneous localization of the lymph nodes with the highest captation of the tracer was done. The gamma probe was programmed to detect the radioactive signal from the F18, instead of the Tc99m that is usual in the sentinel node biopsy technique. Once the hottest point was detected, a short incision was made on this area, and suspicious nodes with the highest uptake registered by the gamma probe were localized and removed. After the surgical removal from the operating field, the surgical pieces stood positive to the gamma probe. Lymph node involvement, and subsequent relapse, was diagnosed before their clinical manifestation. Conclusions This methodology confirms new horizons for the surgical approach of lymph node biopsies in patients with previous tumors with 18F-FDG avidity and suspicion of relapse.

AAR‐LN‐DQ: Automatic anatomy recognition based disease quantification in thoracic lymph node zones via FDG PET/CT images without Nodal Delineation

2020 ◽  
Vol 47 (8) ◽  
pp. 3467-3484
Author(s):  
Guoping Xu ◽  
Jayaram K. Udupa ◽  
Yubing Tong ◽  
Dewey Odhner ◽  
Hanqiang Cao ◽  
...  
Keyword(s):  
Lymph Node ◽  
Fdg Pet ◽  
Ct Images ◽  
Pet Ct ◽  
Thoracic Lymph Node ◽  
Fdg Pet Ct ◽  
Disease Quantification

1596: Lymph Node Staging in Prostate Cancer by the use of 11C-CHOLIN-PET/CT Scan Imaging

2005 ◽  
Vol 173 (4S) ◽  
pp. 432-432
Author(s):  
Georg C. Bartsch ◽  
Norbert Blumstein ◽  
Ludwig J. Rinnab ◽  
Richard E. Hautmann ◽  
Peter M. Messer ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Ct Scan ◽  
Lymph Node Staging ◽  
Pet Ct ◽  
Pet Ct Scan

Diagnostic performance of 18F-FDG PET/CT, ultrasonography and MRI

2014 ◽  
Vol 53 (03) ◽  
pp. 89-94 ◽  
Author(s):  
D. H. Lee ◽  
J.-K Yoon ◽  
S. J. Lee ◽  
T. H. Kim ◽  
D. K. Kang ◽  
...  
Keyword(s):  
Lymph Node ◽  
Fdg Pet ◽  
Axillary Lymph Node ◽  
Diagnostic Performance ◽  
Axillary Lymph ◽  
Diagnostic Ability ◽  
Node Metastasis ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

SummaryThe aim of this study was to evaluate the diagnostic abilities of 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) compared with those of ultrasonography and magnetic resonance imaging (MRI) for axillary lymph node staging in breast cancer patients. Patients, methods: Pre- operative 18F-FDG PET/non-contrast CT, ultrasonography and MRI were performed in 215 women with breast cancer. Axillary lymph node dissection was performed in all patients and the diagnostic performance of each modality was evaluated using histopathologic assessments as the reference standard. ROC curves were compared to evaluate the diagnostic ability of several imaging modalities (i. e., ultrasonography, MRI and 18F-FDG PET/CT). Results: In total, 132 patients (61.4%) had axillary lymph node metastasis. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy for the detection of axillary lymph node metastasis were 72.3%, 77.3%, 66.7%, 81.6%, 75.3% for ultrasonography, 67.5%, 78.0%, 65.9%, 79.2%, 74.0% for MRI, and 62.7%, 88.6%, 77.6%, 79.1%, 78.6% for 18F-FDG PET/CT, respectively. There was no significant difference in diagnostic ability among the imaging modalities (i.e., ultrasonography, MRI and 18F-FDG PET/CT). The diagnostic ability of 18F-FDG PET/CT was significantly improved by combination with MRI (p = 0.0002) or ultrasonography (p < 0.0001). The combination of 18F-FDG PET/CT with ultrasonography had a similar diagnostic ability to that of all three modalities combined (18F-FDG PET/CT+ultraso- nography+MRI, p = 0.05). Conclusion: The diagnostic performance of 18F-FDG PET/CT for detection of axillary node metastasis was not significantly different from that of ultrasonography or MRI in breast cancer patients. Combining 18F-FDG PET/CT with ultrasonography or MRI could improve the diagnostic performance compared to 18F-FDG PET/CT alone.

scholarly journals Textural Features of Pretreatment 18F-FDG PET/CT Images: Prognostic Significance in Patients with Advanced T-Stage Oropharyngeal Squamous Cell Carcinoma

2013 ◽  
Vol 54 (10) ◽  
pp. 1703-1709 ◽  
Author(s):  
N.-M. Cheng ◽  
Y.-H. Dean Fang ◽  
J. Tung-Chieh Chang ◽  
C.-G. Huang ◽  
D.-L. Tsan ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Fdg Pet ◽  
Prognostic Significance ◽  
Ct Images ◽  
Textural Features ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

scholarly journals Multi-factorial considerations for intra-thoracic lymph node evaluations of healthy cats on computed tomographic images

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Ninlawan Thammasiri ◽  
Chutimon Thanaboonnipat ◽  
Nan Choisunirachon ◽  
Damri Darawiroj
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Ct Images ◽  
Slice Thickness ◽  
Maximum Width ◽  
Post Contrast ◽  
Computed Tomographic ◽  
Contrast Enhanced Ct ◽  
Contrast Enhanced ◽  
Enhanced Ct

Abstract Background It is difficult to examine mild to moderate feline intra-thoracic lymphadenopathy via and thoracic radiography. Despite previous information from computed tomographic (CT) images of intra-thoracic lymph nodes, some factors from animals and CT setting were less elucidated. Therefore, this study aimed to investigate the effect of internal factors from animals and external factors from the CT procedure on the feasibility to detect the intra-thoracic lymph nodes. Twenty-four, client-owned, clinically healthy cats were categorized into three groups according to age. They underwent pre- and post-contrast enhanced CT for whole thorax followed by inter-group evaluation and comparison of sternal, cranial mediastinal, and tracheobronchial lymph nodes. Results Post contrast-enhanced CT appearances revealed that intra-thoracic lymph nodes of kittens were invisible, whereas the sternal, cranial mediastinal, and tracheobronchial nodes of cats aged over 7 months old were detected (6/24, 9/24 and 7/24, respectively). Maximum width of these lymph nodes were 3.93 ± 0.74 mm, 4.02 ± 0.65 mm, and 3.51 ± 0.62 mm, respectively. By age, lymph node sizes of these cats were not significantly different. Transverse lymph node width of males was larger than that of females (P = 0.0425). Besides, the detection score of lymph nodes was affected by slice thickness (P < 0.01) and lymph node width (P = 0.0049). Furthermore, an irregular, soft tissue structure, possibly the thymus, was detected in all juvenile cats and three mature cats. Conclusions Despite additional information on intra-thoracic lymph nodes in CT images, which can be used to investigate lymphatic-related abnormalities, age, sex, and slice thickness of CT images must be also considered.

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