Motion correction for improving the accuracy of dual-energy myocardial perfusion CT imaging

2016 ◽  
Author(s):  
Jed D. Pack ◽  
Zhye Yin ◽  
Guanglei Xiong ◽  
Priya Mittal ◽  
Simon Dunham ◽  
...  
Keyword(s):  
Myocardial Perfusion ◽  
Motion Correction ◽  
Dual Energy ◽  
Ct Imaging ◽  
Perfusion Ct

scholarly journals Low-dose dynamic myocardial perfusion CT imaging using a motion adaptive sparsity prior

2017 ◽  
Vol 44 (9) ◽  
pp. e188-e201 ◽  
Author(s):  
Zhaoying Bian ◽  
Dong Zeng ◽  
Zhang Zhang ◽  
Changfei Gong ◽  
Xiumei Tian ◽  
...  
Keyword(s):  
Myocardial Perfusion ◽  
Low Dose ◽  
Ct Imaging ◽  
Perfusion Ct

scholarly journals Development of Coronary Vasospasm during Adenosine-Stress Myocardial Perfusion CT Imaging

2015 ◽  
Vol 16 (3) ◽  
pp. 673 ◽  
Author(s):  
Jeong Gu Nam ◽  
Seong Hoon Choi ◽  
Byeong Seong Kang ◽  
Min Seo Bang ◽  
Woon Jeong Kwon
Keyword(s):  
Myocardial Perfusion ◽  
Ct Imaging ◽  
Perfusion Ct ◽  
Coronary Vasospasm ◽  
Adenosine Stress ◽  
Stress Myocardial Perfusion

scholarly journals Correlation of iodine uptake and perfusion parameters between dual-energy CT imaging and first-pass dual-input perfusion CT in lung cancer

Medicine ◽  
2017 ◽  
Vol 96 (28) ◽  
pp. e7479 ◽  
Author(s):  
Xiaoliang Chen ◽  
Yanyan Xu ◽  
Jianghui Duan ◽  
Chuandong Li ◽  
Hongliang Sun ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Dual Energy ◽  
Ct Imaging ◽  
Perfusion Ct ◽  
Iodine Uptake ◽  
Dual Energy Ct ◽  
First Pass

scholarly journals Motion correction for routine X-ray lung CT imaging

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Doil Kim ◽  
Jiyoung Choi ◽  
Duhgoon Lee ◽  
Hyesun Kim ◽  
Jiyoung Jung ◽  
...  
Keyword(s):  
Motion Estimation ◽  
Motion Correction ◽  
Ct Imaging ◽  
Motion Artifacts ◽  
Ct Scans ◽  
Breath Hold ◽  
X Ray ◽  
Wide Range ◽  
Thorax Ct ◽  
Lung Ct

AbstractA novel motion correction algorithm for X-ray lung CT imaging has been developed recently. It was designed to perform for routine chest or thorax CT scans without gating, namely axial or helical scans with pitch around 1.0. The algorithm makes use of two conjugate partial angle reconstruction images for motion estimation via non-rigid registration which is followed by a motion compensated reconstruction. Differently from other conventional approaches, no segmentation is adopted in motion estimation. This makes motion estimation of various fine lung structures possible. The aim of this study is to explore the performance of the proposed method in correcting the lung motion artifacts which arise even under routine CT scans with breath-hold. The artifacts are known to mimic various lung diseases, so it is of great interest to address the problem. For that purpose, a moving phantom experiment and clinical study (seven cases) were conducted. We selected the entropy and positivity as figure of merits to compare the reconstructed images before and after the motion correction. Results of both phantom and clinical studies showed a statistically significant improvement by the proposed method, namely up to 53.6% (p < 0.05) and up to 35.5% (p < 0.05) improvement by means of the positivity measure, respectively. Images of the proposed method show significantly reduced motion artifacts of various lung structures such as lung parenchyma, pulmonary vessels, and airways which are prominent in FBP images. Results of two exemplary cases also showed great potential of the proposed method in correcting motion artifacts of the aorta which is known to mimic aortic dissection. Compared to other approaches, the proposed method provides an excellent performance and a fully automatic workflow. In addition, it has a great potential to handle motions in wide range of organs such as lung structures and the aorta. We expect that this would pave a way toward innovations in chest and thorax CT imaging.

Abstract TP10: Prediction of Thrombolytic Efficacy: Usefulness of Measurement of Enhancement in the Thrombus on Thin-reconstructed Perfusion CT

Stroke ◽  
2016 ◽  
Vol 47 (suppl_1) ◽  
Author(s):  
Dong Hoon Shin ◽  
Eung Yeop Kim
Keyword(s):  
Collateral Circulation ◽  
Motion Correction ◽  
Hounsfield Unit ◽  
Spiral Ct ◽  
Perfusion Ct ◽  
Vascular Imaging ◽  
Escape Trial ◽  
Tissue Plasminogen ◽  
Noncontrast Ct

Purpose: To directly measure enhancement in acute thrombi using thin-reconstructed perfusion CT images for prediction thrombolytic efficacy. Materials and Methods: Prior to administration of tissue plasminogen activator (tPA), noncontrast CT (NCCT), 60-second 70-kVp adaptive 4D spiral CT (CTP), and CT angiography (CTA) were prospectively obtained and reconstructed at 1-mm thickness. Length and Hounsfield unit ratio (HUr) of thrombus were measured using 1-mm NCCT. Collateral circulation was assessed on dynamic CTA that were reconstructed from 1-mm CTP images. Good collateral circulation was defined as the criteria that were used for ESCAPE trial. After spatial motion correction of 1-mm CTP images, circular regions of interest were drawn in the central portion and each end of thrombus to measure the level of HU increase from baseline on time-attenuation curves (TAC). Recanalization was assessed on follow-up vascular imaging studies that were obtained within 24 hours after tPA. Modified TICI 2b or 3 was considered successful recanalization. Thrombus length, HUr, collaterals, and minimum increase of HU on TAC (HUmin) were compared between the recanalized and non-recanalized groups. Results: Of 57 patients who received tPA therapy, 31 patients (female, 13; mean age, 66.5 years) with occlusions in ICA (n=7), M1 (n=8), M1-M2 (n=6), and M2 (n=10) were only assessed. Thrombus length ranged 3-45 mm (median, 12 mm; IQR, 7). HUr was measured from 1.03 to 1.69 (median, 1.26; IQR, 0.19). Good collaterals were noted in 27 patients. HUmin ranged 3-70 HU (median, 15; IQR, 12), and showed negative correlation with thrombus length (rho=-0.410, P=0.022), but not with HUr. HUmin was significantly higher in the recanalized group (n=19) than the non-recanalized group (mean HUmin 23.79 vs 7.83; P<0.0001) independent of thrombus location. Thrombus length, HUr, or collateral status was not significantly different between the two groups. HUmin > 13 was determined with sensitivity of 89.5%, specificity of 91.7%, and AUC of 0.961 for prediction of recanalization. Conclusion: HUmin of thrombus was significantly higher in patients with successful recanalization after tPA therapy.

Abstract P327: Utilizing Iodine Contrast Extravasation Post Reperfusion and Dual Energy Ct Imaging to Predict Risk of Hemorrhagic Conversion in Acute Stroke Patients

Stroke ◽  
2021 ◽  
Vol 52 (Suppl_1) ◽  
Author(s):  
Tri Huynh* ◽  
Niran Vijayaraghavan* ◽  
Hannah Branstetter ◽  
Natalie Buchwald ◽  
Justin De Prey ◽  
...  
Keyword(s):  
Acute Stroke ◽  
Infarct Volume ◽  
Reperfusion Therapy ◽  
Dual Energy ◽  
Ct Imaging ◽  
Dual Energy Ct ◽  
Stroke Patients ◽  
Post Intervention ◽  
Contrast Extravasation ◽  
Post Contrast

Introduction: Hyperintense acute reperfusion marker (HARM) has been identified on post-contrast magnetic resonance imaging (MRI) to be a marker of hemorrhagic conversion (HC) post reperfusion therapy in acute stroke patients. We have previously described a case where MRI HARM was mimicked on post contrast computed topography (CT) imaging in an acute stroke patient post reperfusion. Dual-Energy (DECT) allows for differentiation between acute blood and iodine contrast extravasation (ICE), and thus can have utility when ICE is present. Here we sought to validate whether post-intervention ICE/CT hyperdensity reperfusion maker (CT HARM), and contrast subtracted on DECT is associated with HC in acute stroke patients. Method: Data was obtained from our Institutional Review Board approved stroke admission database from January 2017 to November 2019, including ischemic stroke patients that received thrombolysis or thrombectomy, had evaluable images within 24 hours of admission, and received a DECT. Ischemic volumes of the stroke was measured on diffusion-weighted image (DWI). ICE was measured on CT head and DECT using the freehand 3D region of interest tool on the Visage Imaging PACS System. Susceptibility weighted MRI sequences were used to grade HC. Data analysis was conducted with regression modeling. Results: A total of 82 patients were included, 49% women, median age 73 (interquartile range (IQR), 61- 77), admission NIHSS 12 (IQR, 7 - 21), 24 hour change in NIHSS 4 (IQR, 0 -13), glucose 125 (IQR, 106 -158), creatinine 1.0 (IQR, 0.8 - 1.2), infarct volume 50.6 ± 7.1 mL, 48% treated with thrombectomy, 7% with PH-1 or PH-2 identified on MRI, and 56% with MCA infarcts. ICE volume was 2.6 ± 1.0 mL and DECT volume was 2.2 ± 1.1mL. ICE increased the likelihood of MRI confirmed PH-1 or PH-2 hemorrhagic conversion (odds ratio (OR) 14.34, 95% confidence interval (CI) 5.74 - 22.94) and decreased likelihood of increase in NIHSS at 24 hours (OR 0.20, 95% CI 0.01 to 0.40). There were no other significant associations with ICE or DECT volumes. Conclusion: Our results are supportive of our proposed association between CT HARM and risk of HC. More studies are needed to study whether quantitative of DECT can be predictive of stroke outcomes post reperfusion therapy.

scholarly journals Improved differentiation between high- and low-grade gliomas by combining dual-energy CT analysis and perfusion CT

Medicine ◽  
2018 ◽  
Vol 97 (32) ◽  
pp. e11670 ◽  
Author(s):  
Yoko Kaichi ◽  
Fuminari Tatsugami ◽  
Yuko Nakamura ◽  
Yasutaka Baba ◽  
Makoto Iida ◽  
...  
Keyword(s):  
Dual Energy ◽  
Perfusion Ct ◽  
Dual Energy Ct ◽  
Low Grade ◽  
Low Grade Gliomas ◽  
Ct Analysis
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