Quantification of volumetric cerebral blood flow using hybrid laser speckle contract and optical coherence tomography (Conference Presentation)

2016 ◽  
Author(s):  
Niksa Valim ◽  
Andrew K. Dunn
Keyword(s):  
Blood Flow ◽  
Optical Coherence Tomography ◽  
Cerebral Blood Flow ◽  
Laser Speckle ◽  
Optical Coherence

scholarly journals Modern Diagnostic Techniques for the Assessment of Ocular Blood Flow in Myopia: Current State of Knowledge

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Ewa Grudzińska ◽  
Monika Modrzejewska
Keyword(s):  
Blood Flow ◽  
Optical Coherence Tomography ◽  
Refractive Error ◽  
Retinal Vessel ◽  
Ocular Blood Flow ◽  
Laser Speckle ◽  
Doppler Imaging ◽  
Optical Coherence ◽  
Contrast Imaging ◽  
Doppler Flowmetry

Myopia is the most common refractive error and the subject of interest of various studies assessing ocular blood flow. Increasing refractive error and axial elongation of the eye result in the stretching and thinning of the scleral, choroid, and retinal tissues and the decrease in retinal vessel diameter, disturbing ocular blood flow. Local and systemic factors known to change ocular blood flow include glaucoma, medications and fluctuations in intraocular pressure, and metabolic parameters. Techniques and tools assessing ocular blood flow include, among others, laser Doppler flowmetry (LDF), retinal function imager (RFI), laser speckle contrast imaging (LSCI), magnetic resonance imaging (MRI), optical coherence tomography angiography (OCTA), pulsatile ocular blood flowmeter (POBF), fundus pulsation amplitude (FPA), colour Doppler imaging (CDI), and Doppler optical coherence tomography (DOCT). Many researchers consistently reported lower blood flow parameters in myopic eyes regardless of the used diagnostic method. It is unclear whether this is a primary change that causes secondary thinning of ocular tissues or quite the opposite; that is, the mechanical stretching of the eye wall reduces its thickness and causes a secondary lower demand of tissues for oxygen. This paper presents a review of studies assessing ocular blood flow in myopes.

scholarly journals Quantitative cerebral blood flow with Optical Coherence Tomography

2010 ◽  
Vol 18 (3) ◽  
pp. 2477 ◽  
Author(s):  
Vivek J. Srinivasan ◽  
Sava Sakadžić ◽  
Iwona Gorczynska ◽  
Svetlana Ruvinskaya ◽  
Weicheng Wu ◽  
...  
Keyword(s):  
Blood Flow ◽  
Optical Coherence Tomography ◽  
Cerebral Blood Flow ◽  
Optical Coherence

scholarly journals Optical coherence tomography for the quantitative study of cerebrovascular physiology

2011 ◽  
Vol 31 (6) ◽  
pp. 1339-1345 ◽  
Author(s):  
Vivek J Srinivasan ◽  
Dmitriy N Atochin ◽  
Harsha Radhakrishnan ◽  
James Y Jiang ◽  
Svetlana Ruvinskaya ◽  
...  
Keyword(s):  
Blood Flow ◽  
Optical Coherence Tomography ◽  
Cerebral Blood Flow ◽  
Quantitative Study ◽  
Quantitative Method ◽  
Tissue Perfusion ◽  
Optical Coherence ◽  
Branch Points ◽  
Clearance Flow ◽  
Hydrogen Clearance

Doppler optical coherence tomography (DOCT) and OCT angiography are novel methods to investigate cerebrovascular physiology. In the rodent cortex, DOCT flow displays features characteristic of cerebral blood flow, including conservation along nonbranching vascular segments and at branch points. Moreover, DOCT flow values correlate with hydrogen clearance flow values when both are measured simultaneously. These data validate DOCT as a noninvasive quantitative method to measure tissue perfusion over a physiologic range.

Quantitative Cerebral Blood Flow and Angiography with Optical Coherence Tomography

2010 ◽  
Author(s):  
Vivek J. Srinivasan ◽  
Dmitriy N. Atochin ◽  
James Y. Jiang ◽  
Harsha Radhakrishnan ◽  
Mohammed A. Yaseen ◽  
...  
Keyword(s):  
Blood Flow ◽  
Optical Coherence Tomography ◽  
Cerebral Blood Flow ◽  
Optical Coherence
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