A novel 1050nm handheld OCT imaging system for pediatric retinoblastoma patients: technology development and clinical study (Conference Presentation)

2016 ◽  
Author(s):  
Oleg Nadiarnykh ◽  
Annette C. Moll ◽  
Johannes F. de Boer
Keyword(s):  
Clinical Study ◽  
Technology Development ◽  
Imaging System ◽  
Oct Imaging

Feasibility and Clinical Utility of Ultra-Widefield–Navigated Swept-Source Optical Coherence Tomography Imaging

2021 ◽  
pp. 247412642199733
Author(s):  
Kyle D. Kovacs ◽  
M. Abdallah Mahrous ◽  
Luis Gonzalez ◽  
Benjamin E. Botsford ◽  
Tamara L. Lenis ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Clinical Utility ◽  
Clinical Decision Making ◽  
Imaging System ◽  
Imaging Modality ◽  
Case Series ◽  
Subretinal Fluid ◽  
Optical Coherence ◽  
Swept Source ◽  
Oct Imaging

Purpose: This work aims to evaluate the clinical utility and feasibility of a novel scanning laser ophthalmoscope-based navigated ultra-widefield swept-source optical coherence tomography (UWF SS-OCT) imaging system. Methods: A retrospective, single-center, consecutive case series evaluated patients between September 2019 and October 2020 with UWF SS-OCT (modified Optos P200TxE, Optos PLC) as part of routine retinal care. The logistics of image acquisition, interpretability of images captured, nature of the peripheral abnormality, and clinical utility in management decisions were recorded. Results: Eighty-two eyes from 72 patients were included. Patients were aged 59.4 ± 17.1 years (range, 8-87 years). During imaging, 4.4 series of images were obtained in 4.1 minutes, with 86.4% of the image series deemed to be diagnostic of the peripheral pathology on blinded image review. The most common pathologic findings were chorioretinal scars (18 eyes). In 31 (38%) eyes, these images were meaningful in supporting clinical decision-making with definitive findings. Diagnoses imaged included retinal detachment combined with retinoschisis, retinal hole with overlying vitreous traction and subretinal fluid, vitreous inflammation overlying a peripheral scar, Coats disease, and peripheral retinal traction in sickle cell retinopathy. Conclusions: Navigated UWF SS-OCT imaging was clinically practical and provided high-quality characterization of peripheral retinal lesions for all eyes. Images directly contributed to management plans, including laser, injection or surgical treatment, for a clinically meaningful set of patients (38%). Future studies are needed to further assess the value of this imaging modality and its role in diagnosing, monitoring, and treating peripheral lesions.

scholarly journals Synthetic polarization-sensitive optical coherence tomography by deep learning

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Yi Sun ◽  
Jianfeng Wang ◽  
Jindou Shi ◽  
Stephen A. Boppart
Keyword(s):  
Optical Coherence Tomography ◽  
Deep Learning ◽  
Imaging System ◽  
Imaging Modality ◽  
Similarity Index ◽  
Polarization Sensitivity ◽  
Imaging Method ◽  
Optical Coherence ◽  
The Real ◽  
Oct Imaging

AbstractPolarization-sensitive optical coherence tomography (PS-OCT) is a high-resolution label-free optical biomedical imaging modality that is sensitive to the microstructural architecture in tissue that gives rise to form birefringence, such as collagen or muscle fibers. To enable polarization sensitivity in an OCT system, however, requires additional hardware and complexity. We developed a deep-learning method to synthesize PS-OCT images by training a generative adversarial network (GAN) on OCT intensity and PS-OCT images. The synthesis accuracy was first evaluated by the structural similarity index (SSIM) between the synthetic and real PS-OCT images. Furthermore, the effectiveness of the computational PS-OCT images was validated by separately training two image classifiers using the real and synthetic PS-OCT images for cancer/normal classification. The similar classification results of the two trained classifiers demonstrate that the predicted PS-OCT images can be potentially used interchangeably in cancer diagnosis applications. In addition, we applied the trained GAN models on OCT images collected from a separate OCT imaging system, and the synthetic PS-OCT images correlate well with the real PS-OCT image collected from the same sample sites using the PS-OCT imaging system. This computational PS-OCT imaging method has the potential to reduce the cost, complexity, and need for hardware-based PS-OCT imaging systems.

scholarly journals Axial Motion Compensation Of Optical Coherence Tomography With A Collaborative Medical Robot

2021 ◽  
Author(s):  
Robnier Reyes Perez
Keyword(s):  
Optical Coherence Tomography ◽  
Motion Compensation ◽  
Imaging System ◽  
Imaging Modality ◽  
Tumor Resection ◽  
Optic Axis ◽  
Robotic Arm ◽  
Optical Coherence ◽  
Axial Motion ◽  
Oct Imaging

This thesis presents an imaging tool consisting of an Optical Coherence Tomography (OCT) imaging system mounted on a collaborative robotic arm to enable axial motion compensation. Optical Coherence Tomography is a subsurface, high-resolution imaging modality used in neuroimaging to differentiate between pathological and non-pathological tissue. The motivation behind this project is to bring Optical Coherence Tomography to the operating room for neuroimaging to help with cancerous tissue differentiation and maximize the extent of tumor resection. However, neurosurgeons have expressed concern with respect to intracranial pressure (ICP) pulsation displacing the brain far off the optic axis of the imaging system so as to not be visible. The collaborative robotic arm compensates for sample motion along the optic axis using a Proportional controller to track the position of the peak intensity of the sample’s intensity profile, which generally corresponds to the sample surface. Collaborative robots have changed the robot industry paradigm becoming increasingly functional and safer than the previous generations of robotic arms. We present an OCT robot end-effector to test the feasibility of performing OCT imaging with the collaborative robot.

IVUS-OCT Imaging System for Detection of Intravascular Lipid Plaque

2018 ◽  
Vol 55 (8) ◽  
pp. 081701
Author(s):  
徐勇 Xu Yong ◽  
汪毅 Wang Yi ◽  
邱建榕 Qiu Jianrong ◽  
沈毅 Shen Yi ◽  
肖禹泽 Xiao Yuze ◽  
...  
Keyword(s):  
Imaging System ◽  
Oct Imaging
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