In-vivo, real-time cross-sectional images of retina using a GPU enhanced master slave optical coherence tomography system

2016 ◽  
Author(s):  
Adrian Bradu ◽  
Konstantin Kapinchev ◽  
Frederick Barnes ◽  
Adrian Podoleanu
Keyword(s):  
Optical Coherence Tomography ◽  
Real Time ◽  
Optical Coherence ◽  
Cross Sectional ◽  
Optical Coherence Tomography System ◽  
Tomography System

scholarly journals Modern Trends in Imaging V: Optical Coherence Tomography for Rapid Tissue Screening and Directed Histological Sectioning

2012 ◽  
Vol 35 (3) ◽  
pp. 129-143 ◽  
Author(s):  
Woonggyu Jung ◽  
Stephen A. Boppart
Keyword(s):  
Optical Coherence Tomography ◽  
Real Time ◽  
Image Guidance ◽  
Diagnostic Yield ◽  
Imaging Modality ◽  
Imaging Techniques ◽  
Optical Coherence ◽  
Sampling Errors ◽  
Cross Sectional

In pathology, histological examination of the “gold standard” to diagnose various diseases. It has contributed significantly toward identifying the abnormalities in tissues and cells, but has inherent drawbacks when used for fast and accurate diagnosis. These limitations include the lack ofin vivoobservation in real time and sampling errors due to limited number and area coverage of tissue sections. Its diagnostic yield also varies depending on the ability of the physician and the effectiveness of any image guidance technique that may be used for tissue screening during excisional biopsy. In order to overcome these current limitations of histology-based diagnostics, there are significant needs for either complementary or alternative imaging techniques which perform non-destructive, high resolution, and rapid tissue screening. Optical coherence tomography (OCT) is an emerging imaging modality which allows real-time cross-sectional imaging with high resolutions that approach those of histology. OCT could be a very promising technique which has the potential to be used as an adjunct to histological tissue observation when it is not practical to take specimens for histological processing, when large areas of tissue need investigating, or when rapid microscopic imaging is needed. This review will describe the use of OCT as an image guidance tool for fast tissue screening and directed histological tissue sectioning in pathology.

scholarly journals GPU accelerated real-time multi-functional spectral-domain optical coherence tomography system at 1300nm

2012 ◽  
Vol 20 (14) ◽  
pp. 14797 ◽  
Author(s):  
Yan Wang ◽  
Christian M. Oh ◽  
Michael C. Oliveira ◽  
M. Shahidul Islam ◽  
Arthur Ortega ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Real Time ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Optical Coherence Tomography System ◽  
Tomography System

scholarly journals Measurement of Oral Epithelial Thickness by Optical Coherence Tomography

Diagnostics ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 90 ◽  
Author(s):  
Stasio ◽  
Lauritano ◽  
Iquebal ◽  
Romano ◽  
Gentile ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Oral Cavity ◽  
Real Time ◽  
Optical Coherence ◽  
Cross Sectional ◽  
Tissue Microstructure ◽  
Imaging Device ◽  
Epithelial Thickness ◽  
Healthy Mucosa

Optical coherence tomography (OCT) is a real-time, in-situ, non-invasive imaging device that is able to perform a cross-sectional evaluation of tissue microstructure based on the specific intensity of back-scattered and reflected light. The aim of the present study was to define normal values of epithelial thickness within the oral cavity. OCT measurements of epithelial thickness were performed in 28 healthy patients at six different locations within the oral cavity. Image analysis was performed using Image J 1.52 software. The healthy epithelium has a mean thickness of 335.59 ± 150.73 µm. According to its location within the oral cavity, the epithelium showed highest values in the region of the buccal mucosa (659.79 µm) and the thinnest one was observed in the mouth’s floor (100.07 µm). OCT has been shown to be useful for the evaluation of oral mucosa in vivo and in real time. Our study provides reference values for the epithelial thickness of multiple sites within the oral cavity. Knowledge of the thickness values of healthy mucosa is, therefore, of fundamental importance.

Sign in / Sign up

Export Citation Format

Share Document