scholarly journals System of polarization phasometry of polycrystalline blood plasma networks in mammary gland pathology diagnostics

2015 ◽  
Author(s):  
Natalia I. Zabolotna ◽  
Bogdan P. Oliinychenko ◽  
Kostiantyn O. Radchenko ◽  
Anastasiia K. Krasnoshchoka ◽  
Olga K. Shcherba
Keyword(s):  
Mammary Gland ◽  
Blood Plasma

THE FEASIBILITIES OF USING THE STATISTICAL, FRACTAL AND SINGULAR PROCESSING OF HOMINAL BLOOD PLASMA PHASE IMAGES DURING THE DIAGNOSTICS AND DIFFERENTIATION OF MAMMARY GLAND PATHOLOGICAL STATES

2012 ◽  
Vol 05 (01) ◽  
pp. 1150001 ◽  
Author(s):  
YU. A. USHENKO
Keyword(s):  
Mammary Gland ◽  
Blood Plasma ◽  
Statistical Approach ◽  
Power Spectra ◽  
Thin Layers ◽  
Fractal Approach ◽  
Phase Images ◽  
Orthogonal Components ◽  
Self Similar ◽  
Plasma Phase

Performed in this work are complex statistical, fractal and singular analyses of phase properties inherent to birefringence networks of protein crystals consisting of optically-thin layers prepared from blood plasma. Within the framework of a statistical approach, the authors have investigated values and ranges for changes of statistical moments of the first to the fourth orders that characterize coordinate distributions for phase shifts between orthogonal components of amplitudes inherent to laser radiation transformed by blood plasma with various pathologies. In the framework of the fractal approach, determined are the dimensions of self-similar coordinate phase distributions as well as features of transformation of logarithmic dependences for power spectra of these distributions for various types of hominal mammary gland pathologies.

scholarly journals Uptake and metabolism of tryptophan by the isolated perfused guinea-pig mammary gland

1976 ◽  
Vol 158 (3) ◽  
pp. 659-662 ◽  
Author(s):  
B Mepham ◽  
A R Peters ◽  
S R Davis
Keyword(s):  
Amino Acids ◽  
Mammary Gland ◽  
Guinea Pig ◽  
Blood Plasma ◽  
Milk Protein ◽  
Absorption Studies ◽  
Uptake And Metabolism ◽  
Tryptophan Uptake

Tryptophan uptake by the isolated perfused lactating guinea-pig mammary gland was 46.5+/-4.6 mug/h per g. Results of absorption studies and the use of [methylene-14C]tryptophan suggest that tryptophan is one of the group of amino acids that are transferred almost quantitatively from blood plasma to milk protein.

scholarly journals Changes in the activity of adenosine deaminase and the content of polyamines in the blood of cats with breast cancer

2019 ◽  
Vol 135 ◽  
pp. 01076
Author(s):  
Maya Vakulenko ◽  
Natalya Akinina ◽  
Natalya Dobaeva ◽  
Elena Bakurova ◽  
Alexey Ermakov
Keyword(s):  
Breast Cancer ◽  
Mammary Gland ◽  
Blood Plasma ◽  
Adenosine Deaminase ◽  
Breast Tumors ◽  
Control Group ◽  
Tumor Biomarker ◽  
Malignant Neoplasms ◽  
Breast Hyperplasia

In this work, the clinical significance of changes in the activity of adenosine deaminase (ADA) and the content of polyamines in the blood plasma of cats with breast cancer was studied. There were examined 30 cats aged 1 to 20 years, operated on in veterinary clinics due to spontaneous neoplasms. Histological studies of surgical material were performed to establish nosological forms of the tumor. The results of the measurements showed that there were no significant differences between ADA activity in the blood plasma of cats diagnosed with invasive nonspecific carcinoma and ADA activity in the blood of healthy animals. In the plasma of animals diagnosed with fibroadenomatous breast hyperplasia, ADA activity was reduced by 35% compared with the control group. The content of putrescine in the red blood cells of cats with benign neoplasms of the mammary gland (fibroepithelial hyperplasia) was statistically significantly increased 5 times compared with the control group. In malignant neoplasms of the mammary gland (invasive non-specific carcinoma, tubular cancer and fibrosarcoma), the content of putrescine and spermine in the blood significantly exceeded the control values by 60 and 10 times, respectively, compared with the control group. Thus, the data obtained indicate the possibility of using polyamines in order to improve the accuracy of diagnosis and treatment of cats with breast cancer. The determination of ADA activity in the blood plasma of cats with breast tumors in the early stages of cancer is not an informationally significant indicator as a tumor biomarker.

scholarly journals UTILIZATION OF GLYCOPROTEIN OF THE BLOOD PLASMA BY THE LACTATING MAMMARY GLAND

1941 ◽  
Vol 138 (1) ◽  
pp. 83-90
Author(s):  
E.P. Reineke ◽  
M.B. Williamson ◽  
C.W. Turner
Keyword(s):  
Mammary Gland ◽  
Blood Plasma ◽  
Lactating Mammary Gland

scholarly journals The concentration of triiodothyronine and thyroxine in colostrum, milk and plasma of cows

2020 ◽  
Vol 22 (98) ◽  
pp. 69-73
Author(s):  
A. V. Pan’kiv ◽  
M. R. Simonov
Keyword(s):  
Mammary Gland ◽  
Thyroid Hormones ◽  
Blood Plasma ◽  
Enzyme Linked Immunosorbent Assay ◽  
Limiting Factor ◽  
Metabolic Processes ◽  
High Concentration ◽  
Biological Origin ◽  
Black And White ◽  
Negative Effect

Milk contains key nutrients in optimal proportions, which makes it to be an important component of the human diet. Despite the fact that consumers receive with milk a significant amount of readily available nutrients, milk can be a source of dangerous factors of chemical and biological origin. The level of physiological hormones found in milk is not a limiting factor and is studied solely for scientific purposes. However, milk hormones can have a negative effect on the health of consumers. Based on this, the aim of this work was to study the concentration of triiodothyronine and thyroxine in colostrum, milk and blood plasma of cows at different stages of lactation. The secretion of the mammary gland and blood plasma of cows of Ukrainian black-and-white dairy breed, in their 2nd–5th lactations with milk yield 5100–5700 kg of milk per previous lactation was the object of the study. The concentration of triiodothyronine and thyroxine using enzyme-linked immunosorbent assay was investigated in withdrawn samples. The obtained data indicates that the highest level of secretion of iodine-containing thyroid hormones with milk is observed on 1st–4th days of lactation. Thereafter, the concentration of hormones in milk statistically significant decreases by 2.8–3-fold (P ˂ 0.001) till 30–40th day of lactation. The high concentration of iodine-containing hormones in colostrum allows to enhance metabolic processes in calves. Studies of the concentration of thyroid hormones in the blood plasma of cows showed a gradual increase from the beginning of lactation till 10th–14th and then till 30th–40th days of lactation. By 10th–14th days we observed 2.2-fold growth of triiodothyronine level (P ˂ 0.001), and till 30th–40th days this parameter has increased by another 12.5 %. The level of thyroxine on 10th–14th days of lactation was higher, compared to such in the beginning of lactation by 62.2 % (P ˂ 0.001), and by 30th–40th day increase was by 40.9 %. The main reasons for such changes are the formation of lactation dominant, the discharge of hormones secreted by the breast and the stimulation of metabolic processes during lactation. The prospects of further research lie in investigation of the dependence of triiodothyronine and thyroxine levels in the secretion of the mammary gland on productivity, breed, age and diet of animals.

scholarly journals Blood and urine concentrations of vascular endothelial growth factor in dogs with tumours

2021 ◽  
Vol 24 (4) ◽  
pp. 596-600
Author(s):  
Ts. T. Hristov ◽  
R. G. Binev
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Mammary Gland ◽  
Growth Factor ◽  
Blood Plasma ◽  
Vascular Endothelial Cells ◽  
Vascular Endothelial ◽  
Mammary Gland Carcinoma ◽  
Urine Concentrations ◽  
Gland Carcinoma ◽  
Endothelial Growth Factor

Vascular endothelial growth factor (VEGF) is a potent mitogen for vascular endothelial cells. It improves cell survival, stimulates angiogenesis, inhibits cell apoptosis and strongly enhances vascular permeability. In this study, VEGF concentrations were assayed in blood plasma and urine of 22 dogs with neoplasms (lymphosarcoma, splenic haemangiosarcoma and mammary gland carcinoma) and in 7 healthy dogs by means of ELISA. Average blood plasma VEGF in control dogs was 42.13 ± 7.37 pg/mL, while in dogs with lymphoma – 113.35 ± 16.48 pg/mL, in dogs with haemangiosarcoma – 154.85 ± 48.46 pg/mL and in dogs with mammary gland carcinoma – 104.31 ± 12.45 pg/mL. Urine VEGF concentrations in dogs affected with lymphosarcoma were 712.42 ± 233.85 ng/g uCr, in animals with haemangiosarcoma – 223.50 ± 262.33 ng/g uCr and in those with mammary carcinoma: 1053.92 ± 311.63 ng/g uCr. In healthy controls average urine VEGF was 310.11 ± 28.11 ng/g uCr.

Extraction of plasma triacylglycerols by the mammary gland of the lactating cow

1991 ◽  
Vol 58 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Gordon E. Thompson ◽  
William W. Christie
Keyword(s):  
Fatty Acids ◽  
Mammary Gland ◽  
Fatty Acid ◽  
Blood Plasma ◽  
Acid Content ◽  
Phytanic Acid ◽  
Fatty Acid Content ◽  
Venous Blood ◽  
The Difference ◽  
Peak Lactation

SummaryThe fatty acid content of triacylglycerols (TG) in arterial and mammary venous blood plasma has been analysed in five cows that were close to peak lactation. The fatty acids in arterial TG were extracted by the mammary gland in amounts 14:0 < 16:0 < 18:0and 18:0 > 18:1n – 9 > 18:2. The difference of extraction between palmitate and stearate was similar in different TG species. The fatty acid 18:1n – 7, which was largely the trans isomer, was extracted more than 18:1n – 9. Significant amounts of phytanic acid were acylated in plasma TG, but not extracted by the mammary gland.

Release of cholesteryl esters by the mammary gland of the pre-partum cow

1989 ◽  
Vol 56 (2) ◽  
pp. 161-165 ◽  
Author(s):  
Gordon E. Thompson
Keyword(s):  
Fatty Acids ◽  
Mammary Gland ◽  
Blood Plasma ◽  
Cholesteryl Esters ◽  
In Blood Plasma

SummaryIn five cows that were regularly milked before parturition, cholesteryl esters were continuously released into the mammary fluid; their concentration in the fluid was initially high, but decreased a few days before parturition when mammary secretion of fluid and triglyceride was increasing. The composition of fatty acids in the cholesteryl esters of mammary fluid and in blood plasma was different, suggesting mammary synthesis of cholesteryl esters.

Calcium and strontium secretion from blood to milk

1961 ◽  
Vol 201 (4) ◽  
pp. 645-650 ◽  
Author(s):  
A. R. Twardock ◽  
C. L. Comar
Keyword(s):  
Mammary Gland ◽  
Blood Plasma ◽  
Renal Tubule ◽  
Blood Stream ◽  
Blood Levels ◽  
Relative Movement ◽  
Intravenous Infusions ◽  
Teat Canal

The mechanisms of Ca and Sr secretion from blood to milk in goats were studied using varying combinations of one radioisotope of Ca and two radioisotopes of Sr and continuous, long-term intravenous infusions as a means of maintaining desired blood levels of stable and radioisotopes of the two elements. Calcium and Sr secretion from blood to milk was the same whether radionuclides were given orally or intravenously; the same was true for radiostrontium excretion by the kidney. Stable Ca infusions gave plasma Ca levels as high as 36 mg %, causing marked decreases in blood and milk levels of ingested Ca45 and Sr85 and reduced renal Ca-Sr discrimination; these results are explainable in terms of a flooding of the renal tubule with stable Ca. Stable Sr infusion gave blood plasma and milk levels as high as 4.6 mg % and 39 mg %, respectively; it caused no change in blood and milk levels of ingested Ca45 but increased levels of ingested Sr89 by a factor of two. The relative movement of Ca and Sr from blood to milk was unaffected by infusions. After stable Ca infusions, plasma stable Ca consistently dropped below preinfusion levels; this may have been due to depression of the parathyroids by high blood Ca. After injection into the mammary gland via the teat canal, equal amounts of Ca45 and Sr85 moved into the blood stream, which indicated the existence of a unidirectional mechanism for preferential movement of calcium over strontium from blood to milk.

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