Simplified approach to characterize optical properties and blood oxygenation in tissue using continuous near-infrared light

1995 ◽  
Author(s):  
Hanli Liu ◽  
David A. Boas ◽  
Yutao Zhang ◽  
Arjun G. Yodh ◽  
Britton Chance
Keyword(s):  
Optical Properties ◽  
Near Infrared ◽  
Blood Oxygenation ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Simplified Approach

Anisotropic optical properties of oriented silver nanorice and nanocarrots in stretched polymer films

Nanoscale ◽  
2015 ◽  
Vol 7 (19) ◽  
pp. 8858-8863 ◽  
Author(s):  
Xia Tong ◽  
Hongyan Liang ◽  
Yanlong Liu ◽  
Long Tan ◽  
Dongling Ma ◽  
...  
Keyword(s):  
Optical Properties ◽  
Polymer Films ◽  
Spectral Region ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light

Oriented arrays of silver nanorice or nanocarrots in stretched polymer films show polarization-dependent transmission of near-infrared light over a wide spectral region.

scholarly journals Near-Infrared Light Increases Functional Connectivity with a Non-thermal Mechanism

2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Grzegorz M Dmochowski ◽  
Ahmed Duke Shereen ◽  
Destiny Berisha ◽  
Jacek P Dmochowski
Keyword(s):  
Magnetic Resonance ◽  
Functional Connectivity ◽  
Time Course ◽  
Near Infrared ◽  
Brain Temperature ◽  
Blood Oxygenation ◽  
Infrared Light ◽  
Frontal Pole ◽  
Healthy Human ◽  
Near Infrared Light

Abstract Although techniques for noninvasive brain stimulation are under intense investigation, an approach that has received limited attention is transcranial photobiomodulation (tPBM), the delivery of near-infrared light to the brain with a laser or light-emitting diode directed at the scalp. Here we employed functional magnetic resonance imaging to measure the blood-oxygenation-level–dependent signal in n = 20 healthy human participants while concurrently stimulating their right frontal pole with a near-infrared laser. Functional connectivity with the illuminated region increased by up to 15% during stimulation, with a quarter of all connections experiencing a significant increase. The time course of connectivity exhibited a sharp rise approximately 1 min after illumination onset. Brain-wide connectivity increases were also observed, with connections involving the stimulated hemisphere showing a significantly larger increase than those in the contralateral hemisphere. We subsequently employed magnetic resonance thermometry to measure brain temperature during tPBM (separate cohort, n = 20) and found no significant temperature differences between active and sham stimulation. Our findings suggest that near-infrared light synchronizes brain activity with a nonthermal mechanism, underscoring the promise of tPBM as a new technique for stimulating brain function.

scholarly journals Near-infrared light increases functional connectivity with a non-thermal mechanism

2018 ◽  
Author(s):  
Grzegorz M. Dmochowski ◽  
Ahmed (Duke) Shereen ◽  
Destiny Berisha ◽  
Jacek P. Dmochowski
Keyword(s):  
Functional Connectivity ◽  
Time Course ◽  
Near Infrared ◽  
Brain Temperature ◽  
Blood Oxygenation ◽  
Infrared Light ◽  
Frontal Pole ◽  
Near Infrared Light ◽  
Healthy Humans ◽  
Thermal Mechanism

AbstractAlthough techniques for non-invasive brain stimulation are under intense investigation, an approach that has received limited attention is transcranial photobiomodulation (tPBM), the delivery of near-infrared light to the brain with a laser directed at the scalp. Here we employed functional magnetic resonance imaging (fMRI) to measure the Blood-Oxygenation-Level Dependent (BOLD) signal in n = 20 healthy humans while concurrently stimulating their right frontal pole with a near-infrared laser. We failed to detect an evoked BOLD response at illumination. However, functional connectivity with the illuminated region increased by an average of 10% during stimulation, with some connections strengthening by as much as 40%. 23% of connections with the illuminated region experienced a significant acute increase, with the time course of connectivity exhibiting a sharp rise at illumination onset. Brain-wide connectivity increases were also observed, with connections in the stimulated hemisphere showing a significantly larger increase than those in the non-stimulated hemisphere. We subsequently employed MR Thermometry to measure brain temperature during tPBM (separate cohort, n = 20), and found no significant temperature differences between active and sham stimulation. Our findings suggest that near-infrared light synchronizes brain activity with a non-thermal mechanism, underscoring the promise of tPBM as a new technique for stimulating brain function.

An ordered copper nanowell-array film with near-perfect broadband absorption from ultraviolet to near-infrared light

2020 ◽  
Vol 59 (11) ◽  
pp. 110906
Author(s):  
Juan Shen ◽  
Yong Ren ◽  
Xinxin Zhu ◽  
Min Mao ◽  
Quan Zhou ◽  
...  
Keyword(s):  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Broadband Absorption

scholarly journals Recent Near-Infrared Light-Activated Nanomedicine toward Precision Cancer Therapy

2021 ◽  
Author(s):  
Xiaowei Luan ◽  
Yongchun Pan ◽  
Yanfeng Gao ◽  
Yujun Song
Keyword(s):  
Cancer Therapy ◽  
Near Infrared ◽  
Infrared Light ◽  
Human Society ◽  
Near Infrared Light ◽  
History Of ◽  
The Universe

Light has witnessed the history of mankind and even the universe. It is of great significances to the life of human society, contributing to energy, agriculture, communication, and much more....

scholarly journals Au–ZnO Conjugated Black Phosphorus as a Near-Infrared Light-Triggering and Recurrence-Suppressing Nanoantibiotic Platform against Staphylococcus aureus

Pharmaceutics ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 52
Author(s):  
Atanu Naskar ◽  
Sohee Lee ◽  
Kwang-sun Kim
Keyword(s):  
Staphylococcus Aureus ◽  
Bacterial Infections ◽  
Near Infrared ◽  
Au Nanoparticles ◽  
Synthesis Method ◽  
Antibacterial Properties ◽  
Black Phosphorus ◽  
Infrared Light ◽  
Resistant Bacteria ◽  
Near Infrared Light

Antibiotic therapy is the gold standard for bacterial infections treatment. However, the rapid increase in multidrug-resistant (MDR) bacterial infections and its recent use for secondary bacterial infections in many COVID-19 patients has considerably weakened its treatment efficacy. These shortcomings motivated researchers to develop new antibacterial materials, such as nanoparticle-based antibacterial platform with the ability to increase the chances of killing MDR strains and prevent their drug resistance. Herein, we report a new black phosphorus (BP)-based non-damaging near-infrared light-responsive platform conjugated with ZnO and Au nanoparticles as a synergistic antibacterial agent against Staphylococcus aureus species. First, BP nanosheets containing Au nanoparticles were assembled in situ with the ZnO nanoparticles prepared by a low-temperature solution synthesis method. Subsequently, the antibacterial activities of the resulting Au–ZnO–BP nanocomposite against the non-resistant, methicillin-resistant, and erythromycin-resistant S. aureus species were determined, after its photothermal efficacy was assessed. The synthesized nanocomposite exhibited excellent anti-S. aureus activity and good photothermal characteristics. The non-resistant S. aureus species did not produce drug-resistant bacteria after the treatment of multiple consecutive passages under the pressure of the proposed nanoantibiotic, but rapidly developed resistance to erythromycin. This work clearly demonstrates the excellent photothermal antibacterial properties of Au–ZnO–BP nanocomposite against the MDR S. aureus species.

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