Clinical applications of a real-time scanning-slit confocal microscope designed for real-time observations of the in-vivo human cornea

1995 ◽  
Author(s):  
Barry R. Masters
Keyword(s):  
Real Time ◽  
Confocal Microscope ◽  
Clinical Applications ◽  
Human Cornea ◽  
Time Scanning

scholarly journals Scanning Slit Confocal Microscopy of the Living Eye

1994 ◽  
Vol 2 (8) ◽  
pp. 3-4
Author(s):  
Barry D. Masters
Keyword(s):  
Real Time ◽  
Optical Design ◽  
Front Surface ◽  
Confocal Microscope ◽  
Human Cornea ◽  
The Real ◽  
Human Eye ◽  
Time Scanning ◽  
Normal Human

The living human eye is in constant motion. The cornea, which is the transparent front surface of the eyeball, is a formidable specimen for microscopy. How can we use a microscope to obtain sufficient contrast in order to observe cellular and subcellular details on a moving, transparent specimen? Although the normal human cornea is free of blood vessels, there are many nerves within the 500 μm thickness of this tissue. How can we observe these nerves in the living human eye?To accomplish these aims, use a new real-time, scanning slit confocal microscope that was developed by Dr. A. Thaer for imaging the in vivo human cornea. The optical design of the real-time, scanning slit confocal microscope is shown as follows in Figure 1. The confocal microscope is a modification of the real-time, scanning slit confocal microscope based on an oscillating too-sided mirror (bi-lateral scanning) which was designed and first constructed in 1969 by G. M. Svishchev in Lenningrad.

Fiber-coupled confocal microscope (FCM) for real time imaging of cellular signals in vivo

2006 ◽  
Author(s):  
Takashi Sakurai ◽  
Seiji Yamamoto ◽  
Atsuo Miyakawa ◽  
Yoshihiko Wakazono ◽  
Takato O. Yoshida ◽  
...  
Keyword(s):  
Real Time ◽  
Confocal Microscope ◽  
Real Time Imaging

scholarly journals Functional Imaging of Colonic Mucosa With a Fibered Confocal Microscope for Real-Time In Vivo Pathology

2007 ◽  
Vol 5 (11) ◽  
pp. 1300-1305 ◽  
Author(s):  
Thomas D. Wang ◽  
Shai Friedland ◽  
Peyman Sahbaie ◽  
Roy Soetikno ◽  
Pei–Lin Hsiung ◽  
...  
Keyword(s):  
Real Time ◽  
Functional Imaging ◽  
Colonic Mucosa ◽  
Confocal Microscope
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