Validation of an enhanced knowledge-based method for segmentation and quantitative analysis of intrathoracic airway trees from three-dimensional CT images

Author(s):  
Milan Sonka ◽  
Wonkyu Park ◽  
Eric A. Hoffman
2021 ◽  
Vol 11 (2) ◽  
pp. 413-423
Author(s):  
Shitao Mao ◽  
Mingjing Zhao ◽  
Shou Liu ◽  
Lijian Wu ◽  
Guangdan Zhao ◽  
...  

In this paper, the three-dimensional segmentation of pulmonary honeycomb lesions and the function of image biomarkers are integrated into a quantitative analysis module of the lung, and integrated into the PACS image diagnosis workstation for the quantitative analysis of doctors. It is difficult to segment honeycomb lesions in lung CT images because of its diffuse and blurred edges, but it has good texture characteristics. Based on this feature, this paper converts honeycomb lesions into a texture classification problem. Firstly, the lung parenchyma is extracted by automatic threshold segmentation and region growing method, and then the lung parenchyma is divided into several small regions according to the texture by watershed method. Then, according to the texture characteristics of each small area, the trained support vector machine is used to classify. Finally, the correlation between gray level and spatial position of slice data is used to correct the classification results, so as to reduce false positive areas. In order to expand the study of imaging biomarkers of chronic lung diseases to more extensive major diseases, a sample database was established for a wide range of multiple lesions. Through feature extraction and feature analysis of multiple lesions in database, potential feature differences can be excavated, which lays a solid foundation for further study of image biomarkers of multiple lesions.


Author(s):  
Tong Wensheng ◽  
Lu Lianhuang ◽  
Zhang Zhijun

This is a combined study of two diffirent branches, photogrammetry and morphology of blood cells. The three dimensional quantitative analysis of erythrocytes using SEMP technique, electron computation technique and photogrammetry theory has made it possible to push the study of mophology of blood cells from LM, TEM, SEM to a higher stage, that of SEM P. A new path has been broken for deeply study of morphology of blood cells.In medical view, the abnormality of the quality and quantity of erythrocytes is one of the important changes of blood disease. It shows the abnormal blood—making function of the human body. Therefore, the study of the change of shape on erythrocytes is the indispensable and important basis of reference in the clinical diagnosis and research of blood disease.The erythrocytes of one normal person, three PNH Patients and one AA patient were used in this experiment. This research determines the following items: Height;Length of two axes (long and short), ratio; Crevice in depth and width of cell membrane; Circumference of erythrocytes; Isoline map of erythrocytes; Section map of erythrocytes.


2012 ◽  
Vol 17 (4) ◽  
pp. 179-190
Author(s):  
Kacper Pluta ◽  
Marcin Janaszewski ◽  
Michał Postolski

Abstract The article presents new conception of 3D model of human bronchial tubes, which represents bronchial tubes extracted from CT images of the chest. The new algorithm which generates new model is an extension of the algorithm (basic algorithm) proposed by Hiroko Kitaoka, Ryuji Takaki and Bela Suki. The basic model has been extended by geometric deformations of branches and noise which occur in bronchial trees extracted from CT images. The article presents comparison of results obtained with the use of the new algorithm and the basic one. Moreover, the discussion of usefulness of generated new models for testing of algorithms for quantitative analysis of bronchial tubes based on CT images is also included.


1998 ◽  
Vol 25 (4) ◽  
pp. 621-630 ◽  
Author(s):  
Yasser Hassan ◽  
Said M Easa

Coordination of highway horizontal and vertical alignments is based on subjective guidelines in current standards. This paper presents a quantitative analysis of coordinating horizontal and sag vertical curves that are designed using two-dimensional standards. The locations where a horizontal curve should not be positioned relative to a sag vertical curve (called red zones) are identified. In the red zone, the available sight distance (computed using three-dimensional models) is less than the required sight distance. Two types of red zones, based on stopping sight distance (SSD) and preview sight distance (PVSD), are examined. The SSD red zone corresponds to the locations where an overlap between a horizontal curve and a sag vertical curve should be avoided because the three-dimensional sight distance will be less than the required SSD. The PVSD red zone corresponds to the locations where a horizontal curve should not start because drivers will not be able to perceive it and safely react to it. The SSD red zones exist for practical highway alignment parameters, and therefore designers should check the alignments for potential SSD red zones. The range of SSD red zones was found to depend on the different alignment parameters, especially the superelevation rate. On the other hand, the results showed that the PVSD red zones exist only for large values of the required PVSD, and therefore this type of red zones is not critical. This paper should be of particular interest to the highway designers and professionals concerned with highway safety.Key words: sight distance, red zone, combined alignment.


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