Automated detection of Schlemm's canal in spectral-domain optical coherence tomography

2015 ◽  
Author(s):  
Manu Tom ◽  
Vignesh Ramakrishnan ◽  
Christian van Oterendorp ◽  
Thomas M. Deserno
Keyword(s):  
Optical Coherence Tomography ◽  
Automated Detection ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Schlemm’S Canal ◽  
Schlemm's Canal

scholarly journals Identification and Assessment of Schlemm's Canal by Spectral-Domain Optical Coherence Tomography

2010 ◽  
Vol 51 (8) ◽  
pp. 4054 ◽  
Author(s):  
Larry Kagemann ◽  
Gadi Wollstein ◽  
Hiroshi Ishikawa ◽  
Richard A. Bilonick ◽  
Peter M. Brennen ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Schlemm’S Canal ◽  
Schlemm's Canal

In vivo biometric evaluation of Schlemm's canal with spectral-domain optical coherence tomography in pseuduexfoliation glaucoma

2016 ◽  
Vol 94 (8) ◽  
pp. e688-e692 ◽  
Author(s):  
Serhat Imamoglu ◽  
Mehmet S. Sevim ◽  
Oksan Alpogan ◽  
Nimet Y. Ercalik ◽  
Esra Turkseven Kumral ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Schlemm’S Canal ◽  
Schlemm's Canal

scholarly journals Anterior Segment Optical Coherence Tomography Signs of Local Dilatation Effect of a Micro-Stent on Schlemm’s Canal

2018 ◽  
Vol 10 (2) ◽  
pp. 184-187
Author(s):  
Kevin Gillmann ◽  
Giorgio Enrico Bravetti ◽  
Kaweh Mansouri ◽  
André Mermoud
Keyword(s):  
Optical Coherence Tomography ◽  
Trabecular Meshwork ◽  
Anterior Segment ◽  
Optical Coherence ◽  
Schlemm’S Canal ◽  
New Device ◽  
Schlemm's Canal ◽  
Canal Diameter ◽  
Trabecular Bypass

Introduction: The iStent inject® (Glaukos Corporation, CA, USA) is a relatively new device designed to be implanted ab-interno through the trabecular meshwork. This is, to the best of our knowledge, the first in-vivo description of a trabecular bypass device visualised with anterior segment optical coherence tomography (AS-OCT), and report of its structural effect on Schlemm’s canal. Case Report: A 74 year-old female patient suffering from long-standing primary open-angle glaucoma and nuclear sclerosis underwent cataract surgery combined with the implantation of two iStent injects®. Surgery was uncomplicated and achieved intraocular pressure (-1 mmHg) and medication (-2 molecules) reduction at 6 months. Under AS-OCT (Spectralis OCT, Heidelberg Engineering AG, Germany) the stent appears as a 300 μm long hyper reflective hollow device within the trabecular meshwork. Approximately a third of it protruded into the anterior chamber. Profound OCT signal loss was notable within the shadow of the device. A second AS-OCT section 500 μm beside the microstent shows a markedly dilated Schlemm’s canal, with a major diameter of 390 μm. Discussions: This report confirms that AS-OCT is a suitable technique to assess microstent positioning, and provides a first report on the in-vivo appearance of a functioning stent. It also indicates that iStent injects® could have a tangible effect on adjacent portions of Schlemm’s canal with, in this case, a 220% increase in canal diameter compared to the observed average (122 μm). This suggests the IOP-lowering effect of trabecular bypass devices could rely on a  dual mechanism involving Schlemm’s canal dilatation.

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