Concept and setup for intraoperative imaging of tumorous tissue via Attenuated Total Reflection spectrosocopy with Quantum Cascade Lasers

2015 ◽  
Author(s):  
Florian B. Geiger ◽  
Martin Koerdel ◽  
Anton Schick ◽  
Axel Heimann ◽  
Kaspar Matiasek ◽  
...  
Keyword(s):  
Quantum Cascade Lasers ◽  
Intraoperative Imaging ◽  
Total Reflection ◽  
Attenuated Total Reflection ◽  
Quantum Cascade ◽  
Cascade Lasers

scholarly journals Sensing chlorinated hydrocarbons via miniaturized GaAs/AlGaAs thin-film waveguide flow cells coupled to quantum cascade lasers

2016 ◽  
Vol 8 (36) ◽  
pp. 6602-6606 ◽  
Author(s):  
Julian Haas ◽  
Robert Stach ◽  
Markus Sieger ◽  
Zana Gashi ◽  
Matthias Godejohann ◽  
...  
Keyword(s):  
Organic Molecules ◽  
Quantum Cascade Lasers ◽  
Total Reflection ◽  
Attenuated Total Reflection ◽  
Mid Infrared ◽  
Flow Cells ◽  
Quantum Cascade ◽  
Low Levels ◽  
Atr Spectroscopy ◽  
Cascade Lasers

Mid-infrared (MIR) sensors based on attenuated total reflection (ATR) spectroscopy provide robust, rapid and sensitive platforms for the detection of low levels of organic molecules and pollutants.

Innovative Substrate-Integrated Hollow Waveguide Coupled Attenuated Total Reflection Sensors for Quantum Cascade Laser Based Infrared Spectroscopy in Harsh Environments

2021 ◽  
pp. 000370282110643
Author(s):  
Andrea Teuber ◽  
Robert Stach ◽  
Julian Haas ◽  
Boris Mizaikoff
Keyword(s):  
Quantum Cascade Lasers ◽  
Evanescent Field ◽  
Total Reflection ◽  
Attenuated Total Reflection ◽  
Ir Radiation ◽  
Metal Structures ◽  
Quantum Cascade ◽  
Hollow Waveguides ◽  
Optical Alignment ◽  
Atr Spectroscopy

An innovative mid-infrared spectroscopic sensor system based on quantum cascade lasers has been developed. The system combines the versatility of substrate-integrated hollow waveguides (IHWGs) with the robustness of attenuated total reflection (ATR) crystals employed as internal reflection waveguides for evanescent field sensing. IHWGs are highly reflective metal structures that propagate infrared (IR) radiation and were used as light pipes for coupling radiation into the ATR waveguide. The combined IHWG-ATR device has been designed such that the utmost stability and robustness of the optical alignment were ensured. This novel assembly enables evanescent field absorption measurements at yet unprecedently harsh conditions, that is, high pressure and temperature. Combining these advantages, this innovative sensor assembly is perfectly suited for taking ATR spectroscopy into the field where the robustness of the assembly and optical alignment is essential.

scholarly journals Infrared Spectroscopy with a Fiber-Coupled Quantum Cascade Laser for Attenuated Total Reflection Measurements Towards Biomedical Applications

Sensors ◽  
2019 ◽  
Vol 19 (23) ◽  
pp. 5130 ◽  
Author(s):  
Ine L. Jernelv ◽  
Karina Strøm ◽  
Dag Roar Hjelme ◽  
Astrid Aksnes
Keyword(s):  
Infrared Spectroscopy ◽  
Quantum Cascade Lasers ◽  
Spectral Power ◽  
Total Reflection ◽  
Attenuated Total Reflection ◽  
Mid Infrared ◽  
Quantum Cascade ◽  
In Vitro Investigation

The development of rapid and accurate biomedical laser spectroscopy systems in the mid-infrared has been enabled by the commercial availability of external-cavity quantum cascade lasers (EC-QCLs). EC-QCLs are a preferable alternative to benchtop instruments such as Fourier transform infrared spectrometers for sensor development as they are small and have high spectral power density. They also allow for the investigation of multiple analytes due to their broad tuneability and through the use of multivariate analysis. This article presents an in vitro investigation with two fiber-coupled measurement setups based on attenuated total reflection spectroscopy and direct transmission spectroscopy for sensing. A pulsed EC-QCL (1200–900 cm − 1 ) was used for measurements of glucose and albumin in aqueous solutions, with lactate and urea as interferents. This analyte composition was chosen as an example of a complex aqueous solution with relevance for biomedical sensors. Glucose concentrations were determined in both setup types with root-mean-square error of cross-validation (RMSECV) of less than 20 mg/dL using partial least-squares (PLS) regression. These results demonstrate accurate analyte measurements, and are promising for further development of fiber-coupled, miniaturised in vivo sensors based on mid-infrared spectroscopy.

PbTe/PbS Multilayer Mirror for EuTe/PbTe Surface Emitting Quantum Cascade Lasers

2009 ◽  
Vol 129 (11) ◽  
pp. 799-801
Author(s):  
Daoshe Cao ◽  
Taiki Yamano ◽  
Yoku Inoue ◽  
Akihiro Ishida
Keyword(s):  
Quantum Cascade Lasers ◽  
Quantum Cascade ◽  
Multilayer Mirror ◽  
Cascade Lasers

Beam Pattern Investigation of Terahertz Quantum Cascade Lasers

PIERS Online ◽  
2008 ◽  
Vol 4 (2) ◽  
pp. 267-270 ◽  
Author(s):  
Saeed Fathololoumi ◽  
Dayan Ban ◽  
Hui Luo ◽  
Peter Grant ◽  
Sylvain R. Laframboise ◽  
...  
Keyword(s):  
Quantum Cascade Lasers ◽  
Beam Pattern ◽  
Quantum Cascade ◽  
Cascade Lasers

Electromagnetic-matter interactions and devices

2017 ◽  
Author(s):  
Sandip Tiwari
Keyword(s):  
Optical Tweezers ◽  
Quantum Cascade Lasers ◽  
Accelerator Physics ◽  
X Ray ◽  
Quantum Cascade ◽  
Inorganic Systems ◽  
Charge Cloud ◽  
Atomic Distance ◽  
Extinction Length ◽  
Cascade Lasers

This chapter explores electromagnetic-matter interactions from photon to extinction length scales, i.e., nanometer of X-ray and above. Starting with Casimir-Polder effect to understand interactions of metals and dielectrics at near-atomic distance scale, it stretches to larger wavelengths to explore optomechanics and its ability for energy exchange and signal transduction between PHz and GHz. This range is explored with near-quantum sensitivity limits. The chapter also develops the understanding phononic bandgaps, and for photons, it explores the use of energetic coupling for useful devices such as optical tweezers, confocal microscopes and atomic clocks. It also explores miniature accelerators as a frontier area in accelerator physics. Plasmonics—the electromagnetic interaction with electron charge cloud—is explored for propagating and confined conditions together with the approaches’ possible uses. Optoelectronic energy conversion is analyzed in organic and inorganic systems, with their underlying interaction physics through solar cells and its thermodynamic limit, and quantum cascade lasers.

Terahertz Quantum Cascade Lasers: Novel Resonators and Linewidth Properties

2007 ◽  
Author(s):  
Lukas Mahler ◽  
Richard P. Green ◽  
Ji-Hua Xu ◽  
Alessandro Tredicucci ◽  
Guido Giuliani ◽  
...  
Keyword(s):  
Quantum Cascade Lasers ◽  
Quantum Cascade ◽  
Cascade Lasers

λ∼3.36 μm room temperature InGaAs/AlAs(Sb) quantum cascade lasers with third order distributed feedback grating

2010 ◽  
Vol 97 (11) ◽  
pp. 111113 ◽  
Author(s):  
J. P. Commin ◽  
K. Kennedy ◽  
D. G. Revin ◽  
S. Y. Zhang ◽  
A. B. Krysa ◽  
...  
Keyword(s):  
Room Temperature ◽  
Quantum Cascade Lasers ◽  
Distributed Feedback ◽  
Third Order ◽  
Quantum Cascade ◽  
Cascade Lasers

scholarly journals Physics and technology of Terahertz quantum cascade lasers

2021 ◽  
Vol 6 (1) ◽  
pp. 1893809
Author(s):  
Miriam S. Vitiello ◽  
Alessandro Tredicucci
Keyword(s):  
Quantum Cascade Lasers ◽  
Quantum Cascade ◽  
Cascade Lasers

Fabrication-Tolerant Design for High-Power, Single-Lobe, Surface-Emitting Quantum Cascade Lasers

2021 ◽  
pp. 1-1
Author(s):  
Jae Ha Ryu ◽  
Chris Sigler ◽  
Jeremy D. Kirch ◽  
Thomas Earles ◽  
Dan Botez ◽  
...  
Keyword(s):  
High Power ◽  
Quantum Cascade Lasers ◽  
Quantum Cascade ◽  
Cascade Lasers
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