scholarly journals Evaluation of the optical interference in a combined measurement system used for assessment of tissue blood flow

2015 ◽  
Author(s):  
Zahra Abdollahi ◽  
Panayiotis A. Kyriacou ◽  
Justin P. Phillips
2018 ◽  
Vol 7 (4.30) ◽  
pp. 131
Author(s):  
Tan Ying Yin ◽  
Farhanahani Mahmud ◽  
Nur Ilyani Ramli

The tissue blood flow (BF) and vascular resistance are the important information for consult peripheral vascular system which related to cardiovascular disease. Unfortunately, most of the current BF monitors are costly, built in huge size and preferable use in hospital and clinic. In the present study, a portable digit skin tissue BF measurement system had been developed using Near-infrared spectroscopy (NIRS) method with simple circuitry and low cost that can be afforded by patients to monitor their cardiovascular information. This system consists of a self-developed NIRS probe; LED and a photodiode, and an Arduino Uno board with MATLAB software as the processing unit. The NIR LED transmits 810 nm light source through biological tissue then detected by the photodiode. The output signal from the NIRS probe is based on resistance changes in the photodiode and by applying the voltage divider law, the signal is further processed by the Arduino with the MATLAB software. Then, according to the modified Lambert-Beer Law in scattering medium, the change in total concentration of haemoglobin ( ) is plotted in order to get a quantitative BF reading which based on its maximum change during venous occlusion. To evaluate the proposed BF measurement system, BF measurement tests had been conducted on four healthy subjects during resting and after exercise. The study had shown that the results of BF after the exercise were in average of 1.5 time higher than the resting BF and this finding agrees with previous research works.


1972 ◽  
Vol 68 (2_Supplb) ◽  
pp. S95-S111 ◽  
Author(s):  
Niels A. Lassen ◽  
Ole Andrée Larsen

ABSTRACT Indicators which freely cross the capillary wall can be used for measurement of tissue blood flow in many different ways. Basically one can distinguish two categories of methods, viz. the ones where the indicator enters the tissue via the inflowing blood and the ones where the indicator is deposited locally in the tissue. The most important methods are briefly described with special emphasis on the theory of blood flow measurement.


1981 ◽  
Vol 240 (5) ◽  
pp. H804-H810 ◽  
Author(s):  
H. D. Kleinert ◽  
H. R. Weiss

Blood flow and high-energy phosphate (HEP) content were determined simultaneously in multiple microregions of left ventricular subendocardium in 29 normal anesthetized open-chest rabbits by use of a new micromethod to determine whether a direct linear relationship existed between these parameters. Tissue samples weighed 1-2 mg. ATP and creatine phosphate (CP) content were quantitated in quick-frozen hearts by fluorometry at sites where tissue perfusion was measured by H2 clearance by use of bare-tipped platinum electrodes. A series of validation studies were conducted to ensure that 1) no significant damage to the tissue surrounding the electrode occurred during the period of experimentation and 2) no significant loss of biochemical constituents had occurred due to labile processes during freezing or storage of the tissue. Blood flow, ATP, and CP values averaged 79.1 +/- 24.1 (SD) ml.min-1.100 g-1, 4.9 +/- 1.3 mumol/g tissue, and 8.0 +/- 3.0 mumol/g tissue, respectively, and are similar to those reported in studies using larger tissue samples. Correlation between the heterogeneous distribution of tissue perfusion and HEP revealed no direct linear relationship between these parameters in the normal unstressed rabbit subendocardium.


2014 ◽  
Vol 494-495 ◽  
pp. 1274-1277
Author(s):  
Kan Liu ◽  
Hao You

This article introduces a measurement system based on LabVIEW used for optical interference fringe on micro-fluidic chips. This system mainly uses cameras to capture real-time images of wedge interference fringe on micro-fluidic chips, then the collected images will be binarized by LabVIEW. The processed images will be divided by zone , determine the flatness and gap thickness of the micro-fluidic chips by interference fringes with different directions of deflection and numbers. Finally, feedback from measured data will be used to adjust the flatness and gap thickness of micro-fluidic chips in order to meet the requirement of tests.


1980 ◽  
Vol 335 (1 Thermal Chara) ◽  
pp. 107-132 ◽  
Author(s):  
Robert C. Eberhart ◽  
Avraham Shitzer ◽  
Ernesto J. Hernandez

Sign in / Sign up

Export Citation Format

Share Document