Towards non-invasive 3D hepatotoxicity assays with optical coherence phase microscopy

2015 ◽  
Author(s):  
Leonard J. Nelson ◽  
Andreas Koulovasilopoulos ◽  
Philipp Treskes ◽  
Peter C. Hayes ◽  
John N. Plevris ◽  
...  
Keyword(s):  
Optical Coherence ◽  
Phase Microscopy ◽  
Non Invasive

scholarly journals Real-time and non-invasive measurements of cell mechanical behaviour with optical coherence phase microscopy

2017 ◽  
Author(s):  
D. Gillies ◽  
W. Gamal ◽  
A. Downes ◽  
Y. Reinwald ◽  
Y. Yang ◽  
...  
Keyword(s):  
Real Time ◽  
Mechanical Behaviour ◽  
Optical Coherence ◽  
Phase Microscopy ◽  
Non Invasive

scholarly journals Real-time and non-invasive measurements of cell mechanical behaviour with optical coherence phase microscopy

Methods ◽  
2018 ◽  
Vol 136 ◽  
pp. 126-133 ◽  
Author(s):  
D. Gillies ◽  
W. Gamal ◽  
A. Downes ◽  
Y. Reinwald ◽  
Y. Yang ◽  
...  
Keyword(s):  
Real Time ◽  
Mechanical Behaviour ◽  
Optical Coherence ◽  
Phase Microscopy ◽  
Non Invasive

scholarly journals Non-invasive three-dimensional thickness analysis of oral epithelium based on optical coherence tomography—development and diagnostic performance

Heliyon ◽  
2021 ◽  
Vol 7 (4) ◽  
pp. e06645
Author(s):  
Charlotte Theresa Trebing ◽  
Sinan Sen ◽  
Stefan Rues ◽  
Christopher Herpel ◽  
Maria Schöllhorn ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Diagnostic Performance ◽  
Three Dimensional ◽  
Oral Epithelium ◽  
Optical Coherence ◽  
Non Invasive

Label-free non-invasive classification of rice seeds using optical coherence tomography assisted with deep neural network

2021 ◽  
Vol 137 ◽  
pp. 106861
Author(s):  
Deepa Joshi ◽  
Ankit Butola ◽  
Sheetal Raosaheb Kanade ◽  
Dilip K. Prasad ◽  
S.V. Amitha Mithra ◽  
...  
Keyword(s):  
Neural Network ◽  
Optical Coherence Tomography ◽  
Deep Neural Network ◽  
Optical Coherence ◽  
Label Free ◽  
Non Invasive ◽  
Rice Seeds

scholarly journals Monitoring New Long-Lasting Intravitreal Formulation for Glaucoma with Vitreous Images Using Optical Coherence Tomography

Pharmaceutics ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 217
Author(s):  
Maria Jesus Rodrigo ◽  
Amaya Pérez del Palomar ◽  
Alberto Montolío ◽  
Silvia Mendez-Martinez ◽  
Manuel Subias ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Relative Intensity ◽  
Therapeutic Option ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Aggregate Size ◽  
Daily Practice ◽  
Optical Coherence ◽  
Non Invasive ◽  
Invasive Method

Intravitreal injection is the gold standard therapeutic option for posterior segment pathologies, and long-lasting release is necessary to avoid reinjections. There is no effective intravitreal treatment for glaucoma or other optic neuropathies in daily practice, nor is there a non-invasive method to monitor drug levels in the vitreous. Here we show that a glaucoma treatment combining a hypotensive and neuroprotective intravitreal formulation (IF) of brimonidine–Laponite (BRI/LAP) can be monitored non-invasively using vitreoretinal interface imaging captured with optical coherence tomography (OCT) over 24 weeks of follow-up. Qualitative and quantitative characterisation was achieved by analysing the changes in vitreous (VIT) signal intensity, expressed as a ratio of retinal pigment epithelium (RPE) intensity. Vitreous hyperreflective aggregates mixed in the vitreous and tended to settle on the retinal surface. Relative intensity and aggregate size progressively decreased over 24 weeks in treated rat eyes as the BRI/LAP IF degraded. VIT/RPE relative intensity and total aggregate area correlated with brimonidine levels measured in the eye. The OCT-derived VIT/RPE relative intensity may be a useful and objective marker for non-invasive monitoring of BRI/LAP IF.

scholarly journals Spectral-domain optical coherence phase microscopy for label-free multiplexed protein microarray assay

2009 ◽  
Vol 25 (2) ◽  
pp. 275-281 ◽  
Author(s):  
Chulmin Joo ◽  
Emre Özkumur ◽  
M. Selim Ünlü ◽  
Johannes F. de Boer
Keyword(s):  
Protein Microarray ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Label Free ◽  
Microarray Assay ◽  
Phase Microscopy

Line‐field confocal optical coherence tomography for non‐invasive diagnosis of lichenoid dermatoses of the childhood: A case series

2021 ◽  
Author(s):  
Linda Tognetti ◽  
Andrea. Carraro ◽  
Elisa Cinotti ◽  
Mariano Suppa ◽  
Veronique Marmol ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Case Series ◽  
Optical Coherence ◽  
Line Field ◽  
Non Invasive
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