A novel excitation-emission wavelength model to facilitate the diagnosis of urinary bladder diseases

2015 ◽  
Author(s):  
Ilya Rafailov ◽  
Scott Palmer ◽  
Karina Litvinova ◽  
Victor Dremin ◽  
Andrey Dunaev ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Emission Wavelength ◽  
Bladder Diseases ◽  
Urinary Bladder Diseases

scholarly journals Intravesical drug delivery approaches for improved therapy of urinary bladder diseases

2021 ◽  
pp. 100100
Author(s):  
Luca Palugan ◽  
Matteo Cerea ◽  
Micol Cirilli ◽  
Saliha Moutaharrik ◽  
Alessandra Maroni ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Urinary Bladder ◽  
Bladder Diseases ◽  
Urinary Bladder Diseases

Association between case signalment and disease diagnosis in urinary bladder disease in Australian cats and dogs

2021 ◽  
pp. 104063872110040
Author(s):  
Emily Jones ◽  
John Alawneh ◽  
Mary Thompson ◽  
Rachel Allavena
Keyword(s):  
Logistic Regression ◽  
Urinary Bladder ◽  
Disease Diagnosis ◽  
Bladder Tissue ◽  
Laboratory Service ◽  
Bladder Disease ◽  
Increased Risk ◽  
Bladder Diseases ◽  
Urinary Bladder Diseases ◽  
The University

Urinary bladder diseases are common in dogs and cats; however, there is little published work on urinary bladder disease in Australian pets. We identified pathology records of Australian dogs and cats with urinary bladder tissue submitted to the University of Queensland Veterinary Laboratory Service during 1994–2016 ( n = 320). We described the proportion of bladder diseases in dogs and cats, and applied the less-commonly used logistic regression procedure to quantify associations between signalment variables and disease diagnosis that were evident using descriptive statistics alone. After preliminary analysis, both species were combined because of similar results. Spayed/castrated animals were 74% less likely to be diagnosed with cystitis compared with intact animals. Animals 4–11 y old were also at lower risk of being diagnosed with cystitis compared with younger or older animals. Male animals were at increased risk of neoplasia compared to females, which contrasts with reports from North America and Europe. There was increased risk for developing neoplasia with progressive age, with up to 20 times higher odds in the > 11-y age group. Logistic regression modeling provided unique insight into proportionate morbidity of urinary bladder diseases in Australian dogs and cats.

Urinary Bladder Diseases

2010 ◽  
pp. 199-199
Author(s):  
Suresh Bakle ◽  
Bipin Daga
Keyword(s):  
Urinary Bladder ◽  
Bladder Diseases ◽  
Urinary Bladder Diseases

scholarly journals Diagnosis of urinary bladder diseases in dogs by using two-dimensional and three-dimensional ultrasonography

2015 ◽  
Vol 8 (7) ◽  
pp. 819-822 ◽  
Author(s):  
Dinesh Dehmiwal ◽  
S.M. Behl ◽  
Prem Singh ◽  
Rishi Tayal ◽  
Madan Pal ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Three Dimensional ◽  
Two Dimensional ◽  
Bladder Diseases ◽  
Urinary Bladder Diseases

scholarly journals Predicting Diagnosis of Australian Canine and Feline Urinary Bladder Disease Based on Histologic Features

2020 ◽  
Vol 7 (4) ◽  
pp. 190
Author(s):  
Emily Jones ◽  
John Alawneh ◽  
Mary Thompson ◽  
Chiara Palmieri ◽  
Karen Jackson ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Urinary Bladder ◽  
Cognitive Biases ◽  
Disease Modeling ◽  
Disease Model ◽  
Statistical Technique ◽  
Regression Modeling ◽  
Bladder Disease ◽  
Logistic Regression Modeling ◽  
Bladder Diseases

Anatomic pathology is a vital component of veterinary medicine but as a primarily subjective qualitative or semiquantitative discipline, it is at risk of cognitive biases. Logistic regression is a statistical technique used to explain relationships between data categories and outcomes and is increasingly being applied in medicine for predicting disease probability based on medical and patient variables. Our aims were to evaluate histologic features of canine and feline bladder diseases and explore the utility of logistic regression modeling in identifying associations in veterinary histopathology, then formulate a predictive disease model using urinary bladder as a pilot tissue. The histologic features of 267 canine and 71 feline bladder samples were evaluated, and a logistic regression model was developed to identify associations between the bladder disease diagnosed, and both patient and histologic variables. There were 102 cases of cystitis, 84 neoplasia, 42 urolithiasis and 63 normal bladders. Logistic regression modeling identified six variables that were significantly associated with disease outcome: species, urothelial ulceration, urothelial inflammation, submucosal lymphoid aggregates, neutrophilic submucosal inflammation, and moderate submucosal hemorrhage. This study demonstrated that logistic regression modeling could provide a more objective approach to veterinary histopathology and has opened the door toward predictive disease modeling based on histologic variables.

Effect of verapamil on cytoplasmic distribution of granules and microfilaments in amphibian urinary bladder

1988 ◽  
Vol 46 ◽  
pp. 324-325
Author(s):  
A.J. Mia ◽  
L.X. Oakford ◽  
T. Yorio
Keyword(s):  
Urinary Bladder ◽  
Water Flow ◽  
Morphological Changes ◽  
Granular Cell ◽  
Cytosolic Calcium ◽  
Calcium Storage ◽  
Amphibian Urinary Bladder ◽  
Vesicular Membrane ◽  
High Concentrations ◽  
Cytoskeletal System

The amphibian urinary bladder has been used as a ‘model’ system for studies of the mechanism of action of antidiuretic hormone (ADH) in stimulating transepithelial water flow. The increase in water permeability is accompanied by morphological changes that include the stimulation of apical microvilli, mobilization of microtubules and microfilaments and vesicular membrane fusion events . It has been shown that alterations in the cytosolic calcium concentrations can inhibit ADH transmembrane water flow and induce alterations in the epithelial cell cytomorphology, including the cytoskeletal system . Recently, the subapical granules of the granular cell in the amphibian urinary bladder have been shown to contain high concentrations of calcium, and it was suggested that these cytoplasmic constituents may act as calcium storage sites for intracellular calcium homeostasis. The present study utilizes the calcium antagonist, verapamil, to examine the effect of calcium deprivation on the cytomorphological features of epithelial cells from amphibian urinary bladder, with particular emphasis on subapical granule and microfilament distribution.

Role of PKC isozymes in water transport in toad urinary bladder

1991 ◽  
Vol 49 ◽  
pp. 302-303
Author(s):  
A.J. Mia ◽  
L.X. Oakford ◽  
T. Yorio
Keyword(s):  
Urinary Bladder ◽  
Apical Membrane ◽  
Membrane Surface ◽  
Protein A ◽  
Cell Types ◽  
Leukemic Cells ◽  
Toad Urinary Bladder ◽  
Pkc Isozymes ◽  
Antibody Labeling

Protein kinase C (PKC) isozymes, when activated, are translocated to particulate membrane fractions for transport to the apical membrane surface in a variety of cell types. Evidence of PKC translocation was demonstrated in human megakaryoblastic leukemic cells, and in cardiac myocytes and fibroblasts, using FTTC immunofluorescent antibody labeling techniques. Recently, we reported immunogold localizations of PKC subtypes I and II in toad urinary bladder epithelia, following 60 min stimulation with Mezerein (MZ), a PKC activator, or antidiuretic hormone (ADH). Localization of isozyme subtypes I and n was carried out in separate grids using specific monoclonal antibodies with subsequent labeling with 20nm protein A-gold probes. Each PKC subtype was found to be distributed singularly and in discrete isolated patches in the cytosol as well as in the apical membrane domains. To determine if the PKC isozymes co-localized within the cell, a double immunogold labeling technique using single grids was utilized.

1199: Chronic Ischemia of the Urinary Bladder Causes Luts in Elderly Women and Men

2007 ◽  
Vol 177 (4S) ◽  
pp. 395-396
Author(s):  
Germar M. Pinggera ◽  
Leo Pallwein ◽  
Ferdinand Frauscher ◽  
Michael Mitterberger ◽  
Fritz Aigner ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Elderly Women ◽  
Chronic Ischemia
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