Real-time clutter reduction in epi-optoacoustic imaging of human volunteers

2014 ◽  
Author(s):  
Michael Jaeger ◽  
Kujtim Gashi ◽  
Sara Peeters ◽  
Gerrit Held ◽  
Stefan Preisser ◽  
...  
Keyword(s):  
Real Time ◽  
Optoacoustic Imaging ◽  
Human Volunteers ◽  
Clutter Reduction

Increase of penetration depth in real-time clinical epi-optoacoustic imaging: clutter reduction and aberration correction

2014 ◽  
Author(s):  
Michael Jaeger ◽  
Kujtim Gashi ◽  
Sara Peeters ◽  
Gerrit Held ◽  
Stefan Preisser ◽  
...  
Keyword(s):  
Real Time ◽  
Penetration Depth ◽  
Aberration Correction ◽  
Optoacoustic Imaging ◽  
Clutter Reduction

scholarly journals Real-time clinical clutter reduction in combined epi-optoacoustic and ultrasound imaging

2014 ◽  
Vol 3 (4) ◽  
Author(s):  
Michael Jaeger ◽  
Kujtim Gashi ◽  
Hidayet Günhan Akarçay ◽  
Gerrit Held ◽  
Sara Peeters ◽  
...  
Keyword(s):  
Real Time ◽  
Imaging System ◽  
Direct Integration ◽  
Illumination System ◽  
Human Volunteers ◽  
Key Factor ◽  
Imaging Depth ◽  
Flexible Imaging ◽  
Clutter Reduction ◽  
Broad Clinical Application

AbstractFlexible imaging of the human body, a requirement for broad clinical application, is obtained by direct integration of optoacoustic (OA) imaging with echo ultrasound (US) in a multimodal epi-illumination system. Up to date, successful deep epi-OA imaging is difficult to achieve owing to clutter. Clutter signals arise from optical absorption in the region of tissue irradiation and strongly reduce contrast and imaging depth. Recently, we developed a displacement-compensated averaging (DCA) technique for clutter reduction based on the clutter decorrelation that occurs when palpating the tissue. To gain first clinical experience on the practical value of DCA, we implemented this technique in a combined clinical OA and US imaging system. Our experience with freehand scanning of human volunteers reveals that real-time feedback on the clutter-reduction outcome is a key factor for achieving superior contrast and imaging depth.

Real-time three-dimensional optoacoustic imaging using an acoustic lens system

2004 ◽  
Vol 85 (5) ◽  
pp. 846-848 ◽  
Author(s):  
J. J. Niederhauser ◽  
M. Jaeger ◽  
M. Frenz
Keyword(s):  
Real Time ◽  
Three Dimensional ◽  
Lens System ◽  
Optoacoustic Imaging ◽  
Acoustic Lens

Advances in real-time multispectral optoacoustic imaging and its applications

2015 ◽  
Vol 9 (4) ◽  
pp. 219-227 ◽  
Author(s):  
Adrian Taruttis ◽  
Vasilis Ntziachristos
Keyword(s):  
Real Time ◽  
Optoacoustic Imaging

Real-time handheld multispectral optoacoustic imaging

2013 ◽  
Vol 38 (9) ◽  
pp. 1404 ◽  
Author(s):  
Andreas Buehler ◽  
Marcin Kacprowicz ◽  
Adrian Taruttis ◽  
Vasilis Ntziachristos
Keyword(s):  
Real Time ◽  
Optoacoustic Imaging

A combined platform for b-mode and real-time optoacoustic imaging based on raw data acquisition

2008 ◽  
Author(s):  
Marc Fournelle ◽  
Kirsten Maass ◽  
Heinrich Fonfara ◽  
Hans-Joachim Welsch ◽  
Manfred Moses ◽  
...  
Keyword(s):  
Data Acquisition ◽  
Real Time ◽  
Optoacoustic Imaging ◽  
Raw Data

scholarly journals Il-18 Overproduction Associated with NLRP1 Single Nucleotide Polymorphisms Linked to Risk for Vitiligo

2021 ◽  
Vol 6 (2) ◽  
Keyword(s):  
Gene Expression ◽  
Single Nucleotide Polymorphisms ◽  
Autoimmune Diseases ◽  
Real Time ◽  
Real Time Pcr ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Risk Genotype ◽  
Human Volunteers ◽  
Cytokine Levels

Background The NLRP1gene is central to the NLR inflammasome. Variants to the NLRP1 gene are associated with vitiligo and other autoimmune diseases. We examined the effects of two single nucleotide polymorphisms (SNP) son cytokine levels and NLRP1 gene expression in 50 human volunteers. Methods NLRP1 was genotyped at SNPs rs2670660 and rs12150220, and participants who were homozygous at one or more SNP were analyzed. Plasma IL-18 and IL-1β levels were quantified using ELISA. NLRP1 gene expression was measured using real-time PCR. Results Participants with the risk genotype had significantly higher levels of plasma IL-18 than participants with protective genotype (0.439 ng/µL compared to 0.152 ng/µL, p = 0.024). Genotypes rs2670660 and rs12150220 were strongly linked in this population (p = 2.33 x 10-13). Conclusions Increased production of IL-18, suggests that at least one of the AA variants of rs2670660 or rs12150220 increases NLRP1 activity. rs2670660 and rs12150220 are strongly linked.

scholarly journals Functional Real-Time Optoacoustic Imaging of Middle Cerebral Artery Occlusion in Mice

PLoS ONE ◽  
2014 ◽  
Vol 9 (4) ◽  
pp. e96118 ◽  
Author(s):  
Moritz Kneipp ◽  
Jake Turner ◽  
Sebastian Hambauer ◽  
Sandro M. Krieg ◽  
Jens Lehmberg ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Middle Cerebral Artery Occlusion ◽  
Real Time ◽  
Cerebral Artery ◽  
Artery Occlusion ◽  
Optoacoustic Imaging ◽  
Cerebral Artery Occlusion
Sign in / Sign up

Export Citation Format

Share Document