Quantitative spectrally resolved intraoperative fluorescence imaging for neurosurgical guidance in brain tumor surgery: pre-clinical and clinical results

2014 ◽  
Author(s):  
Pablo A. Valdés ◽  
Valerie L. Jacobs ◽  
Frederic Leblond ◽  
Brian C. Wilson ◽  
Keith D. Paulsen ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Fluorescence Imaging ◽  
Clinical Results ◽  
Tumor Surgery ◽  
Brain Tumor Surgery ◽  
Spectrally Resolved ◽  
Intraoperative Fluorescence Imaging ◽  
Intraoperative Fluorescence

Clinical guidelines for the use of intraoperative fluorescence diagnosis in brain tumor surgery

2015 ◽  
Vol 79 (5) ◽  
pp. 91 ◽  
Author(s):  
A. A. Potapov ◽  
S. A. Goryaynov ◽  
V. A. Okhlopkov ◽  
D. I. Pitskhelauri ◽  
G. L. Kobyakov ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Clinical Guidelines ◽  
Tumor Surgery ◽  
Brain Tumor Surgery ◽  
Fluorescence Diagnosis ◽  
Intraoperative Fluorescence

scholarly journals Fluorescence-Guided Surgery: A Review on Timing and Use in Brain Tumor Surgery

2021 ◽  
Vol 12 ◽  
Author(s):  
Alexander J. Schupper ◽  
Manasa Rao ◽  
Nicki Mohammadi ◽  
Rebecca Baron ◽  
John Y. K. Lee ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Aminolevulinic Acid ◽  
Tumor Surgery ◽  
Brain Tumor Surgery ◽  
Glioma Surgery ◽  
Guided Surgery ◽  
The Past ◽  
Fluorescence Guided Surgery ◽  
The Right ◽  
Intraoperative Fluorescence

Fluorescence-guided surgery (FGS) allows surgeons to have improved visualization of tumor tissue in the operating room, enabling maximal safe resection of malignant brain tumors. Over the past two decades, multiple fluorescent agents have been studied for FGS, including 5-aminolevulinic acid (5-ALA), fluorescein sodium, and indocyanine green (ICG). Both non-targeted and targeted fluorescent agents are currently being used in clinical practice, as well as under investigation, for glioma visualization and resection. While the efficacy of intraoperative fluorescence in studied fluorophores has been well established in the literature, the effect of timing on fluorophore administration in glioma surgery has not been as well depicted. In the past year, recent studies of 5-ALA use have shown that intraoperative fluorescence may persist beyond the previously studied window used in prior multicenter trials. Additionally, the use of fluorophores for different brain tumor types is discussed in detail, including a discussion of choosing the right fluorophore based on tumor etiology. In the following review, the authors will describe the temporal nature of the various fluorophores used in glioma surgery, what remains uncertain in FGS, and provide a guide for using fluorescence as a surgical adjunct in brain tumor surgery.

scholarly journals Quantitative, spectrally-resolved intraoperative fluorescence imaging

2012 ◽  
Vol 2 (1) ◽  
Author(s):  
Pablo A. Valdés ◽  
Frederic Leblond ◽  
Valerie L. Jacobs ◽  
Brian C. Wilson ◽  
Keith D. Paulsen ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Spectrally Resolved ◽  
Intraoperative Fluorescence Imaging ◽  
Intraoperative Fluorescence

Machine Learning Algorithm to Predict Early Complications after Brain Tumor Surgery

2018 ◽  
Author(s):  
C.H.B. van Niftrik ◽  
F. van der Wouden ◽  
V. Staartjes ◽  
J. Fierstra ◽  
M. Stienen ◽  
...  
Keyword(s):  
Machine Learning ◽  
Brain Tumor ◽  
Learning Algorithm ◽  
Machine Learning Algorithm ◽  
Tumor Surgery ◽  
Early Complications ◽  
Brain Tumor Surgery

Role of Perioperative Factor XIII in Intracerebral Hemorrhage after Brain Tumor Surgery: A Prospective Study

2019 ◽  
Author(s):  
Estela Val Jordan ◽  
Agustín Nebra Puertas ◽  
Juan Casado Pellejero ◽  
Maria Dolores Vicente Gordo ◽  
Concepción Revilla López ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Intracerebral Hemorrhage ◽  
Prospective Study ◽  
Factor Xiii ◽  
Tumor Surgery ◽  
Brain Tumor Surgery ◽  
A Prospective Study
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