A diffuse reflectance spectroscopy system to study biological tissues

2013 ◽  
Author(s):  
A. de la Cadena ◽  
S. Stolik ◽  
J. M. de la Rosa
2018 ◽  
Vol 26 (6) ◽  
pp. 337-350 ◽  
Author(s):  
Sharmin Akter ◽  
Md. Golzar Hossain ◽  
Izumi Nishidate ◽  
Hisanao Hazama ◽  
Kunio Awazu

Diffuse reflectance spectroscopy is a widely used technique for medical applications that may analyze the optical characteristics of biological tissues. By using diffuse reflectance spectroscopy, different tissue types can be distinguished based on specific changes on reflected light spectrum that are a result of differences on a molecular level between compared tissues. Identification of the structural features of tissue can be performed by applying diffuse reflectance spectroscopy, and the spectra obtained from this technique could provide important diagnostic information about the tissue morphology and physiology. Moreover, different tissue types can be classified using diffuse reflectance spectroscopy, during surgery on the basis of their optical properties that are related to the tissue morphology and constituents. In recent years, several research groups have been shown the feasibility of diffuse reflectance spectroscopy in discriminating benign and malignant tissue, and thus making it a good competitor for margin assessment. Therefore, the diffuse reflectance spectroscopy has the possibility to become an important optical means for disease diagnosis, treatment and prognosis monitoring. This review represents a summary of the literature on diffuse reflectance spectroscopy and its important clinical applications.


Author(s):  
Pedro Martin-Mateos ◽  
Sergio Crespo-Garcia ◽  
Marta Ruiz-Llata ◽  
José Ramón Lopez-Fernandez ◽  
José Luis Jorcano ◽  
...  

2021 ◽  
Vol 2091 (1) ◽  
pp. 012014
Author(s):  
K V Pozhar ◽  
M O Mikhailov ◽  
E A Polyakova ◽  
E L Litinskaia

Abstract The paper considers the method of diffuse reflectance spectroscopy for noninvasive glucose level measuring in biological tissues. It is proposed a portable implementation of the system, based on a laser diode with a wavelength of 1600 nm and a power of 30 mW, operating in a pulsed mode, as well as a set of NIR-photodiodes located around the laser. The measuring system has been tested on model solutions with diffuse reflectance from polystyrene and pigskin. In the course of measurements on fixed system, an error of ~17 mg/dl is observed, which can be reduced by improving miniature laser sources.


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