Continuous-wave near-photon counting spectral imaging detector in the mid-infrared by upconversion

2013 ◽  
Author(s):  
Jeppe Seidelin Dam ◽  
Peter Tidemand-Lichtenberg ◽  
Christian Pedersen
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Petri Paakkari ◽  
Satu I. Inkinen ◽  
Miitu K. M. Honkanen ◽  
Mithilesh Prakash ◽  
Rubina Shaikh ◽  
...  

AbstractPhoton-counting detector computed tomography (PCD-CT) is a modern spectral imaging technique utilizing photon-counting detectors (PCDs). PCDs detect individual photons and classify them into fixed energy bins, thus enabling energy selective imaging, contrary to energy integrating detectors that detects and sums the total energy from all photons during acquisition. The structure and composition of the articular cartilage cannot be detected with native CT imaging but can be assessed using contrast-enhancement. Spectral imaging allows simultaneous decomposition of multiple contrast agents, which can be used to target and highlight discrete cartilage properties. Here we report, for the first time, the use of PCD-CT to quantify a cationic iodinated CA4+ (targeting proteoglycans) and a non-ionic gadolinium-based gadoteridol (reflecting water content) contrast agents inside human osteochondral tissue (n = 53). We performed PCD-CT scanning at diffusion equilibrium and compared the results against reference data of biomechanical and optical density measurements, and Mankin scoring. PCD-CT enables simultaneous quantification of the two contrast agent concentrations inside cartilage and the results correlate with the structural and functional reference parameters. With improved soft tissue contrast and assessment of proteoglycan and water contents, PCD-CT with the dual contrast agent method is of potential use for the detection and monitoring of osteoarthritis.


2007 ◽  
Vol 50 (2-3) ◽  
pp. 211-216 ◽  
Author(s):  
S.V. Bandara ◽  
S.D. Gunapala ◽  
D.Z. Ting ◽  
J.K. Liu ◽  
C.J. Hill ◽  
...  

2013 ◽  
Vol 565 ◽  
pp. 132-137 ◽  
Author(s):  
Dongfeng Zhao ◽  
Joseph Guss ◽  
Anton J. Walsh ◽  
Harold Linnartz

2013 ◽  
Author(s):  
Peter Tidemand-Lichtenberg ◽  
Jeppe Seidelin Dam ◽  
Christian Pedersen

2021 ◽  
Vol 2086 (1) ◽  
pp. 012096
Author(s):  
Aleksei Reutov ◽  
Denis Sych

Abstract Measurement of photon statistics is an important tool for the verification of quantum properties of light. Due to the various imperfections of real single photon detectors, the observed statistics of photon counts deviates from the underlying statistics of photons. Here we analyze statistical properties of coherent states, and investigate a connection between Poissonian distribution of photons and sub-Poissonian distribution of photon counts due to the detector dead-time corrections. We derive a functional dependence between the mean number of photons and the mean number of photon counts, as well as connection between higher-order statistical moments, for the pulsed or continuous wave coherent light sources, and confirm the results by numerical simulations.


1998 ◽  
Vol 10 (5) ◽  
pp. 660-662 ◽  
Author(s):  
W.W. Bewley ◽  
C.L. Felix ◽  
I. Vurgaftman ◽  
E.H. Aifer ◽  
J.R. Meyer ◽  
...  
Keyword(s):  

Author(s):  
Dominik Burghart ◽  
Wolfhard Oberhausen ◽  
Kevin Zhang ◽  
Alexander Gardanow ◽  
Jonas Krakofsky ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document